Latest publications: November 2021

Congratulations to members of the Department who have recently had their research findings published. Here’s our round-up of the latest publication successes.


To ensure the quality and accuracy of the information published on this blog, we source our data directly from Symplectic. Our reports are generated on a monthly basis, which means there may be a delay in publicising some publications.

Title Canonical journal title Publication type Publication date Authors OR Authors/Contributors
The Alpha variant was not associated with excess nosocomial SARS-CoV-2 infection in a multi-centre UK hospital study. Journal of Infection Journal Article 27/10/2021 Boshier FAT, Venturini C, Stirrup O, Guerra-Assunção JA, Alcolea-Medina A, Becket AH, Byott M, Charalampous T, Filipe ADS, Frampton D, Glaysher S, Khan T, Kulasegara-Shylini R, Kele B, Monahan IM, Mollett G, Parker M, Pelosi E, Randell P, Roy S, Taylor JF, Weller SJ, Wilson-Davies E, Wade P, Williams R, Copas AJ, Cutino-Moguel T, Freemantle N, Hayward AC, Holmes A, Hughes J, Mahungu TW, Nebbia G, Nastouli E, Partridge DG, Pope CF, Price JR, Robson SC, Saeed K, Shin GY, de Silva TI, Snell LB, Thomson EC, Witney AA, Breuer J, COG-UK HOCI Variant Substudy consortium*, The COVID-19 Genomics UK (COG-UK) consortium
Eosinophils are part of the granulocyte response in tuberculosis and promote host resistance in mice Journal of Experimental Medicine Article, Journal 04/10/2021 Bohrer AC, Castro E, Hu Z, Queiroz ATL, Tocheny CE, Assmann M, Sakai S, Nelson C, Baker PJ, Ma H, Wang L, Zilu W, du Bruyn E, Riou C, Kauffman KD, Moore IN, Del Nonno F, Petrone L, Goletti D, Martineau AR, Lowe DM, Cronan MR, Wilkinson RJ, Barry CE, Via LE, Barber DL, Klion AD, Andrade BB, Song Y, Wong K-W, Mayer-Barber KD
Our evolving view of neutrophils in defining the pathology of chronic lung disease Immunology Review, Journal 04/10/2021 Mincham KT, Bruno N, Singanayagam A, Snelgrove RJ
Plasma Plasmodium falciparum Histidine-rich Protein 2 Concentrations in Children With Malaria Infections of Differing Severity in Kilifi, Kenya. Clinical Infectious Diseases Journal Article, Research Support, Non-U.S. Gov’t 05/10/2021 Uyoga S, Wanjiku P, Rop JC, Makale J, Macharia AW, Nyutu GM, Shebe M, Awuondo KA, Mturi N, Woodrow CJ, Dondorp AM, Maitland K, Williams TN
Staphylococcal phages and pathogenicity islands drive plasmid evolution Nature Communications Article, Journal 06/10/2021 Humphrey S, San Millan A, Toll-Riera M, Connolly J, Flor-Duro A, Chen J, Ubeda C, Craig MacLean R, Penades JR
Increased Frequency of Inter-Subtype HIV-1 Recombinants Identified by Near Full-Length Virus Sequencing in Rwandan Acute Transmission Cohorts Frontiers in Microbiology Article, Journal 07/10/2021 Umviligihozo G, Muok E, Gisa EN, Xu R, Dilernia D, Herard K, Song H, Qin Q, Bizimana J, Farmer P, Hare J, Gilmour J, Allen S, Karita E, Hunter E, Yue L
Antibiotic persistence and tolerance: not just one and the same. Current Opinion in Microbiology Journal Article, Review 08/10/2021 Ronneau S, Hill PW, Helaine S
Molecular Basis of Lysis-Lysogeny Decisions in Gram-Positive Phages. Annual Review of Microbiology Journal Article 08/10/2021 Brady A, Felipe-Ruiz A, Gallego Del Sol F, Marina A, Quiles-Puchalt N, Penadés JR
Polymeric and lipid nanoparticles for delivery of self-amplifying RNA vaccines Journal of Controlled Release Article, Journal 10/10/2021 Blakney AK, McKay PF, Hu K, Samnuan K, Jain N, Brown A, Thomas A, Rogers P, Polra K, Sallah H, Yeow J, Zhu Y, Stevens MM, Geall A, Shattock RJ
GenoChemetic Strategy for Derivatization of the Violacein Natural Product Scaffold. ACS Chemical Biology Journal Article 14/10/2021 Lai H-E, Obled AMC, Chee SM, Morgan RM, Lynch R, Sharma SV, Moore SJ, Polizzi KM, Goss RJM, Freemont PS
Prevalence of infection by human T Cell lymphotropic viruses (HTLV-1/2) in adult population in Vitória-ES. Brazilian Journal of Infectious Diseases Journal Article 14/10/2021 Orletti MPS, Assone T, Sarnaglia GD, Martins ML, Rosadas C, Casseb J, Taylor G, Ferreira-Filho JB, Pereira FEL, Miranda AE
The Role of Streptococcal Cell-Envelope Proteases in Bacterial Evasion of the Innate Immune System Journal of Innate Immunity Review, Early Access, Journal 14/10/2021 McKenna S, Huse KK, Giblin S, Pearson M, Majid Al Shibar MS, Sriskandan S, Matthews S, Pease JE
How I wrote a pop-science book. Nature Journal article 15/10/2021 Tregoning J
Inactivation of SARS-CoV-2 in chlorinated swimming pool water Water Research Article, Journal 15/10/2021 Brown JC, Moshe M, Blackwell A, Barclay WS
Structural basis for the inhibition of the Bacillus subtilis c-di-AMP cyclase CdaA by the phosphoglucomutase GlmM. Journal of Biological Chemistry Journal Article 19/10/2021 Pathania M, Tosi T, Millership C, Hoshiga F, Morgan RML, Freemont PS, Gründling A
The immunology of asymptomatic SARS-CoV-2 infection: what are the key questions? Nature Reviews Immunology Article, Early Access, Journal 19/10/2021 Boyton RJ, Altmann DM
Utility and applicability of rapid diagnostic testing in antimicrobial stewardship in Asia Pacific: A Delphi consensus. Clinical Infectious Diseases Journal Article 19/10/2021 Apisarnthanarak A, Kim HB, Moore LSP, Xiao Y, Singh S, Doi Y, Kwa AL-H, Ponnampalavanar SSLS, Cao Q, Kim S-W, Lee H, Santanirand P
Incidental findings in UK healthy volunteers screened for a COVID-19 vaccine trial Clinical and Translational Science Article, Early Access, Journal 20/10/2021 Hodgson SH, Iveson P, Larwood J, Roche S, Morrison H, Cosgrove C, Galiza E, Ikram S, Lemm N-M, Mehdipour S, Owens D, Pacurar M, Schumacher M, Shaw RH, Faust SN, Heath PT, Pollard AJ, Emary KRW, Pollock KM, Lazarus R
Waning immunity to SARS-CoV-2: implications for vaccine booster strategies. The Lancet Respiratory Medicine Journal Article 21/10/2021 Altmann DM, Boyton RJ
Defining variant-resistant epitopes targeted by SARS-CoV-2 antibodies: A global consortium study Science Article, Journal 22/10/2021 Hastie KM, Li H, Bedinger D, Schendel SL, Dennison SM, Li K, Rayaprolu V, Yu X, Mann C, Zandonatti M, Avalos RD, Zyla D, Buck T, Hui S, Shaffer K, Hariharan C, Yin J, Olmedillas E, Enriquez A, Parekh D, Abraha M, Feeney E, Horn GQ, Aldon Y, Ali H, Aracic S, Cobb RR, Federman RS, Fernandez JM, Glanville J, Green R, Grigoryan G, Hernandez AGL, Ho DD, Huang K-YA, Ingraham J, Jiang W, Kellam P, Kim C, Kim M, Kim HM, Kong C, Krebs SJ, Lan F, Lang G, Lee S, Leung CL, Liu J, Lu Y, MacCamy A, McGuire AT, Palser AL, Rabbitts TH, Tehrani ZR, Sajadi MM, Sanders RW, Sato AK, Schweizer L, Seo J, Shen B, Snitselaar JL, Stamatatos L, Tan Y, Tomic MT, van Gils MJ, Youssef S, Yu J, Yuan TZ, Zhang Q, Peters B, Tomaras GD, Germann T, Saphire EO
Heterologous humoral immunity to human and zoonotic coronaviruses: Aiming for the achilles heel. Seminars in Immunology Journal Article, Review 25/10/2021 Ng KW, Faulkner N, Wrobel AG, Gamblin SJ, Kassiotis G
Adaptive immunity and neutralizing antibodies against SARS-CoV-2 variants of concern following vaccination in patients with cancer: the CAPTURE study Nature Cancer Article, Early Access, Journal 27/10/2021 Fendler A, Shepherd STC, Au L, Wilkinson KA, Wu M, Byrne F, Cerrone M, Schmitt AM, Joharatnam-Hogan N, Shum B, Tippu Z, Rzeniewicz K, Boos LA, Harvey R, Carlyle E, Edmonds K, Del Rosario L, Sarker S, Lingard K, Mangwende M, Holt L, Ahmod H, Korteweg J, Foley T, Bazin J, Gordon W, Barber T, Emslie-Henry A, Xie W, Gerard CL, Deng D, Wall EC, Agua-Doce A, Namjou S, Caidan S, Gavrielides M, MacRae J, Kelly G, Peat K, Kelly D, Murra A, Kelly K, O’Flaherty M, Dowdie L, Ash N, Gronthoud F, Shea RL, Gardner G, Murray D, Kinnaird F, Cui W, Pascual J, Rodney S, Mencel J, Curtis O, Stephenson C, Robinson A, Oza B, Farag S, Leslie I, Rogiers A, Iyengar S, Ethell M, Messiou C, Cunningham D, Chau I, Starling N, Turner N, Welsh L, van As N, Jones RL, Droney J, Banerjee S, Tatham KC, O’Brien M, Harrington K, Bhide S, Okines A, Reid A, Young K, Furness AJS, Pickering L, Swanton C, Gandhi S, Gamblin S, Bauer DL, Kassiotis G, Kumar S, Yousaf N, Jhanji S, Nicholson E, Howell M, Walker S, Wilkinson RJ, Larkin J, Turajlic S
Functional antibody and T cell immunity following SARS-CoV-2 infection, including by variants of concern, in patients with cancer: the CAPTURE study Nature Cancer Article, Early Access, Journal 27/10/2021 Fendler A, Au L, Shepherd STC, Byrne F, Cerrone M, Boos LA, Rzeniewicz K, Gordon W, Shum B, Gerard CL, Ward B, Xie W, Schmitt AM, Joharatnam-Hogan N, Cornish GH, Pule M, Mekkaoui L, Ng KW, Carlyle E, Edmonds K, Del Rosario L, Sarker S, Lingard K, Mangwende M, Holt L, Ahmod H, Stone R, Gomes C, Flynn HR, Agua-Doce A, Hobson P, Caidan S, Howell M, Wu M, Goldstone R, Crawford M, Cubitt L, Patel H, Gavrielides M, Nye E, Snijders AP, MacRae J, Nicod J, Gronthoud F, Shea RL, Messiou C, Cunningham D, Chau I, Starling N, Turner N, Welsh L, van As N, Jones RL, Droney J, Banerjee S, Tatham KC, Jhanji S, O’Brien M, Curtis O, Harrington K, Bhide S, Bazin J, Robinson A, Stephenson C, Slattery T, Khan Y, Tippu Z, Leslie I, Gennatas S, Okines A, Reid A, Young K, Furness AJS, Pickering L, Gandhi S, Gamblin S, Swanton C, Nicholson E, Kumar S, Yousaf N, Wilkinson KA, Swerdlow A, Harvey R, Kassiotis G, Larkin J, Wilkinson RJ, Turajlic S
The vulnerable versatility of Salmonella antibiotic persisters during infection. Cell Host and Microbe Journal Article 27/10/2021 Hill PWS, Moldoveanu AL, Sargen M, Ronneau S, Glegola-Madejska I, Beetham C, Fisher RA, Helaine S
Baseline IL-6 is a biomarker for unfavorable tuberculosis treatment outcomes: a multi-site discovery and validation study. European Respiratory Journal Journal Article 28/10/2021 Gupte AN, Kumar P, Araújo-Pereira M, Kulkarni V, Paradkar M, Pradhan N, Menon P, Chandrasekaran PD, Hanna L-E, Yogendra Shivakumar SVB, Rockwood N, Du Bruyn E, Karyakarte R, Gaikwad S, Bollinger R, Golub J, Gupte N, Viswanathan V, Wilkinson RJ, Mave V, Babu S, Kornfeld H, Andrade BB, Gupta A
Resilience of the respiratory microbiome in controlled adult RSV challenge study. European Respiratory Journal Letter 28/10/2021 Cuthbertson L, James P, Habibi MS, Thwaites RS, Paras A, Chiu C, Openshaw PJM, Cookson WOC, Moffatt MF
A prenylated dsRNA sensor protects against severe COVID-19. Science Journal Article, Research Support, Non-U.S. Gov’t 29/10/2021 Wickenhagen A, Sugrue E, Lytras S, Kuchi S, Noerenberg M, Turnbull ML, Loney C, Herder V, Allan J, Jarmson I, Cameron-Ruiz N, Varjak M, Pinto RM, Lee JY, Iselin L, Palmalux N, Stewart DG, Swingler S, Greenwood EJD, Crozier TWM, Gu Q, Davies EL, Clohisey S, Wang B, Trindade Maranhão Costa F, Freire Santana M, de Lima Ferreira LC, Murphy L, Fawkes A, Meynert A, Grimes G, ISARIC4C Investigators, Da Silva Filho JL, Marti M, Hughes J, Stanton RJ, Wang ECY, Ho A, Davis I, Jarrett RF, Castello A, Robertson DL, Semple MG, Openshaw PJM, Palmarini M, Lehner PJ, Baillie JK, Rihn SJ, Wilson SJ
A Research and Development (R&D) roadmap for influenza vaccines: Looking toward the future Vaccine Review, Journal 29/10/2021 Moore AK, Ostrowsky TJ, Kraigsley MA, Mehr AJ, Bresee JS, Friede MH, Gellin BG, Golding JP, Hart PJ, Moen A, Weller CL, Osterholm MT, Barclay W, Cavaleri M, Cohen C, Cowling B, Cox R, Gust I, Innis B, Kang G, Katz J, Krammer F, Pitisuttithum P, Posts D, Rudenko L, Siqueira M, Weir J
Community transmission and viral load kinetics of the SARS-CoV-2 delta (B.1.617.2) variant in vaccinated and unvaccinated individuals in the UK: a prospective, longitudinal, cohort study. Lancet Infectious Diseases Journal Article 29/10/2021 Singanayagam A, Hakki S, Dunning J, Madon KJ, Crone MA, Koycheva A, Derqui-Fernandez N, Barnett JL, Whitfield MG, Varro R, Charlett A, Kundu R, Fenn J, Cutajar J, Quinn V, Conibear E, Barclay W, Freemont PS, Taylor GP, Ahmad S, Zambon M, Ferguson NM, Lalvani A, ATACCC Study Investigators

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