Latest publications: December 2021

Congratulations to members of the Department who have recently had their research findings published. Here’s our round-up of the latest publication successes.


To ensure the quality and accuracy of the information published on this blog, we source our data directly from Symplectic. Our reports are generated on a monthly basis, which means there may be a delay in publicising some publications.

Title Canonical journal title Publication type Publication date Authors OR Authors/Contributors
Rates of viral suppression in a cohort of people with stable HIV from two community models of ART delivery versus facility-based HIV care in Lusaka, Zambia: a cluster-randomised, non-inferiority trial nested in the HPTN 071 (PopART) trial. The Lancet HIV Journal Article 26/11/2021 Limbada M, Macleod D, Situmbeko V, Muhau E, Shibwela O, Chiti B, Floyd S, Schaap AJ, Hayes R, Fidler S, Ayles H, HPTN 071 (PopART) study team
Comparative transcriptomic analysis reveals translationally relevant processes in mouse models of malaria eLife Journal Article 10/01/2022 Athina Georgiadou, Claire Dunican, Pablo Soro-Barrio, Hyun Jae Lee, Myrsini Kaforou, Aubrey J Cunnington Is a corresponding author
Modelling upper respiratory viral load dynamics of SARS-CoV-2 BMC Medicine Journal Article 13/01/2022 Joseph D. Challenger, Cher Y. Foo, Yue Wu, Ada W. C. Yan, Mahdi Moradi Marjaneh, Felicity Liew, Ryan S. Thwaites, Lucy C. Okell & Aubrey J. Cunnington
Broadening symptom criteria improves early case identification in SARS-CoV-2 contacts. European Respiratory Journal Journal Article 25/11/2021 Houston H, Hakki S, Pillay TD, Madon K, Derqui-Fernandez N, Koycheva A, Singanayagam A, Fenn J, Kundu R, Conibear E, Varro R, Cutajar J, Quinn V, Wang L, Narean JS, Tolosa-Wright MR, Barnett J, Kon OM, Tedder R, Taylor G, Zambon M, Ferguson N, Dunning J, Deeks JJ, Lalvani A
Retrospective analysis of North West London healthcare utilisation by children during the COVID-19 pandemic BMJ Paediatrics Open Journal Article 13/01/2022 Rohan Mongru, Danielle F Rose, Ceire Costelloe, Aubrey Cunnington, Ruud G Nijman
De novo germline mutation in the dual specificity phosphatase 10 gene accelerates autoimmune diabetes. Proceedings of the National Academy of Sciences of USA Journal Article 23/11/2021 Foray A-P, Candon S, Hildebrand S, Marquet C, Valette F, Pecquet C, Lemoine S, Langa-Vives F, Dumas M, Hu P, Santamaria P, You S, Lyon S, Scott L, Bu CH, Wang T, Xu D, Moresco EMY, Scazzocchio C, Bach J-F, Beutler B, Chatenoud L
How to Adapt an Intestinal Microbiota Transplantation program to reduce the risk of invasive multidrug-resistant infection. Clinical Microbiology and Infection Journal Article, Review 23/11/2021 Ghani R, Mullish BH, Davies FJ, Marchesi JR
Identification of FtpA, a Dps-like protein involved in anti-oxidative stress and virulence in Actinobacillus pleuropneumoniae. Journal of Bacteriology Journal article 22/11/2021 Tang H, Zhang Q, Han W, Wang Z, Pang S, Zhu H, Tan K, Liu X, Langford PR, Huang Q, Zhou R, Li L
The arbitrium system controls Prophage induction Current Biology Article, Journal 22/11/2021 Brady A, Quiles-Puchalt N, del Sol FG, Zamora-Caballero S, Felipe-Ruiz A, Val-Calvo J, Meijer WJJ, Marina A, Penades JR
GenoChemetic Strategy for Derivatization of the Violacein Natural Product Scaffold. ACS Chemical Biology Journal Article, Research Support, Non-U.S. Gov’t 19/11/2021 Lai H-E, Obled AMC, Chee SM, Morgan RM, Lynch R, Sharma SV, Moore SJ, Polizzi KM, Goss RJM, Freemont PS
The impact of viral mutations on recognition by SARS-CoV-2 specific T cells. iScience Journal Article 19/11/2021 de Silva TI, Liu G, Lindsey BB, Dong D, Moore SC, Hsu NS, Shah D, Wellington D, Mentzer AJ, Angyal A, Brown R, Parker MD, Ying Z, Yao X, Turtle L, Dunachie S, COVID-19 Genomics UK (COG-UK) Consortium, Maini MK, Ogg G, Knight JC, ISARIC4C Investigators, Peng Y, Rowland-Jones SL, Dong T
Covid-19 caseload in the UK-assessments and mitigations. BMJ: British Medical Journal Journal Article 18/11/2021 Altmann D, Boyton R
Vaccine efficacy and immune interference: co-administering COVID-19 and influenza vaccines. The Lancet Respiratory Medicine Journal Article 17/11/2021 Altmann DM, Boyton RJ
Addressing high-risk antipoaching roles in Central Africa: lessons from delivery of remote advanced first-aid teaching for trauma care and snakebite first aid. Transactions of the Royal Society of Tropical Medicine and Hygiene Journal Article 16/11/2021 Wong SMY, Handford C, Vermaak M, Moore LSP, Pallett SJC
Delineating the impact of COVID-19 on antimicrobial resistance: An Indian perspective. Science of the Total Environment Journal Article, Review 16/11/2021 Seethalakshmi PS, Charity OJ, Giakoumis T, Kiran GS, Sriskandan S, Voulvoulis N, Selvin J
The symptomatology of cerebrospinal fluid HIV RNA escape: a large case-series AIDS Article, Journal 15/11/2021 Chan TY-H, De Zan V, Gregg A, Alagaratnam J, Gerevini S, Antinori A, Monforte AD, Saracino A, Trunfio M, Everitt A, Rackstraw S, Marta M, Calcagno A, Cinque P, Winston A
Blocking T cell egress with FTY720 extends DNA vaccine expression but reduces immunogenicity. Immunology Journal Article 14/11/2021 Mann JFS, McKay PF, Klein K, Pankrac J, Tregoning JS, Shattock RJ
Adjunctive viral cell culture supports treatment decision-making in patients with secondary humoral immunodeficiency and persistent SARS-CoV-2 infection British Journal of Haematology Letter, Early Access, Journal 11/11/2021 Pallett SJC, Wake R, Youngs J, Pope C, Tan NK, Taylor J, Hawkins L, Witney AA, Laing KG, Monahan IM, Akay M, Cox A, Groppelli E, Kelleher P, Miller P, Bicanic T
Deaths in children and young people in England after SARS-CoV-2 infection during the first pandemic year Nature Medicine Article, Early Access, Journal 11/11/2021 Smith C, Odd D, Harwood R, Ward J, Linney M, Clark M, Hargreaves D, Ladhani SN, Draper E, Davis PJ, Kenny SE, Whittaker E, Luyt K, Viner R, Fraser LK
Pediatric Antifungal Prescribing Patterns Identify Significant Opportunities to Rationalize Antifungal Use in Children. The Pediatric Infectious Disease Journal Journal Article 11/11/2021 Ferreras-Antolín L, Irwin A, Atra A, Chapelle F, Drysdale SB, Emonts M, McMaster P, Paulus S, Patel S, Rompola M, Vergnano S, Whittaker E, Warris A
Global surveillance, research, and collaboration needed to improve understanding and management of long COVID. The Lancet Journal Article 10/11/2021 Ward H, Flower B, Garcia PJ, Ong SWX, Altmann DM, Delaney B, Smith N, Elliott P, Cooke G
Pre-existing polymerase-specific T cells expand in abortive seronegative SARS-CoV-2. Nature Journal Article 10/11/2021 Swadling L, Diniz MO, Schmidt NM, Amin OE, Chandran A, Shaw E, Pade C, Gibbons JM, Le Bert N, Tan AT, Jeffery-Smith A, Tan CCS, Tham CYL, Kucykowicz S, Aidoo-Micah G, Rosenheim J, Davies J, Johnson M, Jensen MP, Joy G, McCoy LE, Valdes AM, Chain BM, Goldblatt D, Altmann DM, Boyton RJ, Manisty C, Treibel TA, Moon JC, COVIDsortium investigators, Dorp LV, Balloux F, McKnight Á, Noursadeghi M, Bertoletti A, Maini MK
Structures of Class I and Class II Transcription Complexes Reveal the Molecular Basis of RamA-Dependent Transcription Activation Advanced Science Article, Early Access, Journal 10/11/2021 Hao M, Ye F, Jovanovic M, Kotta-Loizou I, Xu Q, Qin X, Buck M, Zhang X, Wang M
Bacterial chromosomal mobility via lateral transduction exceeds that of classical mobile genetic elements Nature Communications Article, Journal 08/11/2021 Humphrey S, Fillol-Salom A, Quiles-Puchalt N, Ibarra-Chavez R, Haag AF, Chen J, Penades JR
Cerebrospinal Fluid viral load across the spectrum of untreated HIV-1 infection: a cross-sectional multi-center study. Clinical Infectious Diseases Journal Article 08/11/2021 Ulfhammer G, Edén A, Antinori A, Brew BJ, Calcagno A, Cinque P, De Zan V, Hagberg L, Lin A, Nilsson S, Oprea C, Pinnetti C, Spudich S, Trunfio M, Winston A, Price RW, Gisslén M
Improving retention of community-recruited participants in HIV prevention research through Saturday household visits; findings from the HPTN 071 (PopART) study in South Africa BMC Medical Research Methodology Article, Journal 08/11/2021 Bell-Mandla NF, Sloot R, Maarman G, Griffith S, Moore A, Floyd S, Hayes R, Fidler S, Ayles H, Bock P
Lateral transduction is inherent to the life cycle of the archetypical Salmonella phage P22 Nature Communications Article, Journal 08/11/2021 Fillol-Salom A, Bacigalupe R, Humphrey S, Chiang YN, Chen J, Penades JR
SARS-CoV-2 and HIV-1: Should HIV-1-Infected Individuals in Sub-Saharan Africa Be Considered a Priority Group for the COVID-19 Vaccines? Frontiers in Immunology Review, Journal 08/11/2021 Mandala WL, Liu MKP

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