Congratulations to members of the Department who have recently had their research findings published. Here’s our round-up of the latest publication successes.
To ensure the quality and accuracy of the information published on this blog, we source our data directly from Symplectic. Our reports are generated on a monthly basis, which means there may be a delay in publicising some publications.
| Title | Canonical journal title | Publication type | Authors OR Authors/Contributors | Publication date |
| A dual paper-based nucleic acid extraction method from blood in under ten minutes for point-of-care diagnostics. | The Analyst | Journal Article | Malpartida-Cardenas K, Baum J, Cunnington A, Georgiou P, Rodriguez-Manzano J | 26/06/2023 |
| A model for analysis of antibiotic usage in low-income settings. | Journal of Antimicrobial Chemotherapy | Journal Article | Rockwood N, Mani U, Ranawaka S, Gunarathna S, Sivaganesh S | 23/06/2023 |
| An acidic microenvironment in Tuberculosis increases extracellular matrix degradation by regulating macrophage inflammatory responses. | PLoS Pathogens | Journal Article | Whittington AM, Turner FS, Baark F, Templeman S, Kirwan DE, Roufosse C, Krishnan N, Robertson BD, Chong DLW, Porter JC, Gilman RH, Friedland JS | 07/07/2023 |
| ARPC5 deficiency leads to severe early onset systemic inflammation and mortality. | Disease Models and Mechanisms | Journal Article | Sindram E, Caballero-Oteyza A, Kogata N, Huang S, Alizadeh Z, Gamez-Díaz L, Fazlollahi MR, Peng X, Grimbacher B, Way M, Proietti M | 29/06/2023 |
| Asymptomatic immunodeficiency-associated vaccine-derived poliovirus infections in two UK children. | Nature Communications | Journal Article | Singanayagam A, Klapsa D, Burton-Fanning S, Hand J, Wilton T, Stephens L, Mate R, Shillitoe B, Celma C, Slatter M, Flood T, Gopal R, Martin J, Zambon M | 09/06/2023 |
| Asymptomatic Plasmodium falciparum infection evades triggering a host transcriptomic response. | Journal of Infection | Letter | Prah DA, Dunican C, Amoah LE, Marjaneh MM, Kaforou M, Nordgren A, Jones-Warner W, Aniweh Y, Awandare GA, Cunnington AJ, R Hafalla JC | 23/06/2023 |
| Bacterial peritonitis in paediatric appendicitis; microbial epidemiology and antimicrobial management. | Annals of Clinical Microbiology and Antimicrobials | Journal Article | Bhaskar K, Clarke S, Moore LSP, Hughes S | 03/06/2023 |
| Biological and Structural Analyses of New Potent Allosteric Inhibitors of HIV-1 Integrase. | Antimicrobial Agents and Chemotherapy | Journal Article | Bonnard D, Le Rouzic E, Singer MR, Yu Z, Le Strat F, Batisse C, Batisse J, Amadori C, Chasset S, Pye VE, Emiliani S, Ledoussal B, Ruff M, Moreau F, Cherepanov P, Benarous R | 13/06/2023 |
| Decline in nitrosative stress drives antibiotic persister regrowth during infection. | Cell Host and Microbe | Journal Article | Ronneau S, Michaux C, Helaine S | 14/06/2023 |
| Deep Domain Adaptation Enhances Amplification Curve Analysis for Single-Channel Multiplexing in Real-Time PCR. | IEEE Journal of Biomedical and Health Informatics | Journal Article, Research Support, Non-U.S. Gov’t | Mao Y, Xu K, Miglietta L, Kreitmann L, Moser N, Georgiou P, Holmes A, Rodriguez-Manzano J | 01/06/2023 |
| Digerati – A multipath parallel hybrid deep learning framework for the identification of mycobacterial PE/PPE proteins. | Computers in Biology and Medicine | Journal Article | Li F, Guo X, Bi Y, Jia R, Pitt ME, Pan S, Li S, Gasser RB, Coin LJ, Song J | 21/06/2023 |
| Discrepancies in Management of Congenital Cytomegalovirus in Preterm Infants: An International Survey. | The Pediatric Infectious Disease Journal | Journal Article | Petrunin Y, Payne H, Blázquez-Gamero D, Buxmann H, Drysdale SB, Gkentzi D, Papaevangelou V, Lyall H | 08/06/2023 |
| Early evaluation of the safety, reactogenicity, and immune response after a single dose of modified vaccinia Ankara-Bavaria Nordic vaccine against mpox in children: a national outbreak response. | Lancet Infectious Diseases | Journal Article | Ladhani SN, Dowell AC, Jones S, Hicks B, Rowe C, Begum J, Wailblinger D, Wright J, Owens S, Pickering A, Shilltoe B, McMaster P, Whittaker E, Zuo J, Powell A, Amirthalingam G, Mandal S, Lopez-Bernal J, Ramsay ME, Kissane N, Bell M, Watson H, Ho D, Hallis B, Otter A, Moss P, Cohen J | 16/06/2023 |
| Emergency medical services utilisation among febrile children attending emergency departments across Europe: an observational multicentre study. | European Journal of Pediatrics | Journal Article | Tan CD, Vermont CL, Zachariasse JM, von Both U, Eleftheriou I, Emonts M, van der Flier M, Herberg J, Kohlmaier B, Levin M, Lim E, Maconochie IK, Martinon-Torres F, Nijman RG, Pokorn M, Rivero-Calle I, Tsolia M, Zenz W, Zavadska D, Moll HA, Carrol ED, PERFORM consortium (Personalised Risk assessment in febrile children to optimize Real-life Management across the European Union) | 24/06/2023 |
| Evaluating the cost implications of integrating SARS-CoV-2 genome sequencing for infection prevention and control investigation of nosocomial transmission within hospitals. | Journal of Hospital Infection | Journal Article | Panca M, Blackstone J, Stirrup O, Cutino-Moguel M-T, Thomson E, Peters C, Snell LB, Nebbia G, Holmes A, Chawla A, Machin N, Taha Y, Mahungu T, Saluja T, de Silva TI, Saeed K, Pope C, Shin GY, Williams R, Darby A, Smith DL, Loose M, Robson SC, Laing K, Partridge DG, Price JR, Breuer J | 10/06/2023 |
| Evolutionary and functional history of the Escherichia coli K1 capsule. | Nature Communications | Journal Article | Arredondo-Alonso S, Blundell-Hunter G, Fu Z, Gladstone RA, Fillol-Salom A, Loraine J, Cloutman-Green E, Johnsen PJ, Samuelsen Ø, Pöntinen AK, Cléon F, Chavez-Bueno S, De la Cruz MA, Ares MA, Vongsouvath M, Chmielarczyk A, Horner C, Klein N, McNally A, Reis JN, Penadés JR, Thomson NR, Corander J, Taylor PW, McCarthy AJ | 15/06/2023 |
| Genomic screening of 16 UK native bat species through conservationist networks uncovers coronaviruses with zoonotic potential. | Nature Communications | Journal Article | Tan CCS, Trew J, Peacock TP, Mok KY, Hart C, Lau K, Ni D, Orme CDL, Ransome E, Pearse WD, Coleman CM, Bailey D, Thakur N, Quantrill JL, Sukhova K, Richard D, Kahane L, Woodward G, Bell T, Worledge L, Nunez-Mino J, Barclay W, van Dorp L, Balloux F, Savolainen V | 27/06/2023 |
| Host protection by two memory-like MAIT subsets. | Nature Cell Biology | Journal Article, Comment | Dominguez-Villar M | 01/06/2023 |
| Hybrid immunity in older adults is associated with reduced SARS-CoV-2 infections following BNT162b2 COVID-19 immunisation. | Communications Medicine | Journal Article | Pallett SJC, Heskin J, Keating F, Mazzella A, Taylor H, Patel A, Lamb G, Sturdy D, Eisler N, Denny S, Charani E, Randell P, Mughal N, Parker E, de Oliveira CR, Rayment M, Jones R, Tedder R, McClure M, Groppelli E, Davies GW, O’Shea MK, Moore LSP | 16/06/2023 |
| Imaging Spectrum of HTLV-1-Related Neurologic Disease: A Pooled Series and Review. | Neurology: Clinical Practice | Journal Article, Review | Dixon L, McNamara C, Dhasmana D, Taylor GP, Davies N | 01/06/2023 |
| Immune Profiling Panel Gene Set Identifies Critically Ill Patients With Low Monocyte Human Leukocyte Antigen-DR Expression: Preliminary Results From the REAnimation Low Immune Status Marker (REALISM) Study. | Critical Care Medicine | Observational Study, Journal Article | Peronnet E, Blein S, Venet F, Cerrato E, Fleurie A, Llitjos J-F, Kreitmann L, Terraz G, Conti F, Gossez M, Rimmelé T, Textoris J, Lukaszewicz A-C, Brengel-Pesce K, Monneret G, REAnimation Low Immune Status Marker (REALISM) Study Group | 01/06/2023 |
| Immunomodulatory Therapy for MIS-C. | Pediatrics | Journal Article | Ouldali N, Son MBF, McArdle AJ, Vito O, Vaugon E, Belot A, Leblanc C, Murray NL, Patel MM, Levin M, Randolph AG, Angoulvant F, BATS CONSORTIUM, the OVERCOMING COVID-19 INVESTIGATORS, and the FRENCH COVID-19 PEDIATRIC INFLAMMATION CONSORTIUM AND PANDOR STUDY GROUP | 28/06/2023 |
| Impact of the COVID-19 pandemic on antimicrobial stewardship support for general practices in England: a qualitative interview study. | BJGP Open | Journal Article | Campbell A, Borek AJ, McLeod M, Tonkin-Crine S, Pouwels KB, Roope L, Hayhoe BW, Majeed A, Walker AS, Holmes A, STEP-UP team | 08/06/2023 |
| Infant postnatal prophylaxis following maternal viraemia during breastfeeding. | AIDS | Letter | Lees EA, Tickner N, Lyall H, Mcmaster P, Smith B, Cliffe L, Taylor G, Foster C | 01/06/2023 |
| Intranasal immunization with outer membrane vesicles (OMV) protects against airway colonization and systemic infection with Acinetobacter baumannii. | Journal of Infection | Journal Article, Research Support, Non-U.S. Gov’t | Higham SL, Baker S, Flight KE, Krishna A, Kellam P, Reece ST, Tregoning JS | 01/06/2023 |
| KIR-HLA interactions extend human CD8+ T cell lifespan in vivo. | Journal of Clinical Investigation | Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov’t | Zhang Y, Yan AW, Boelen L, Hadcocks L, Salam A, Gispert DP, Spanos L, Bitria LM, Nemat-Gorgani N, Traherne JA, Roberts C, Koftori D, Taylor GP, Forton D, Norman PJ, Marsh SG, Busch R, Macallan DC, Asquith B | 15/06/2023 |
| Large clones of pre-existing T cells drive early immunity against SARS-COV-2 and LCMV infection. | iScience | Journal Article | Milighetti M, Peng Y, Tan C, Mark M, Nageswaran G, Byrne S, Ronel T, Peacock T, Mayer A, Chandran A, Rosenheim J, Whelan M, Yao X, Liu G, Felce SL, Dong T, Mentzer AJ, Knight JC, Balloux F, Greenstein E, Reich-Zeliger S, Pade C, Gibbons JM, Semper A, Brooks T, Otter A, Altmann DM, Boyton RJ, Maini MK, McKnight A, Manisty C, Treibel TA, Moon JC, COVIDsortium Investigators, Noursadeghi M, Chain B | 16/06/2023 |
| Making the Case for All-Oral, Shorter Regimens for Children with Drug-Resistant Tuberculosis. | American Journal of Respiratory and Critical Care Medicine | Journal Article | Patankar S, Cruz AT, Douglas-Jones B, Garcia-Prats A, Kay A, Reuter A, Schaaf HS, Seddon JA, Sharma S, Starke J, Tommasi M, Triasih R, Furin JJ | 05/06/2023 |
| Managing mpox using a remote monitoring service. | Journal of Infection | Letter | Rayment M, Cole S, Heskin J, Khan S, Wright M, Barrett J, Bird J, Scott C, Byrne R, Girometti N, Dosekun O, McSorley J, Wallis G, Bull L, Randell P, Mughal N, Moore LSP, Davies GW, Jones R | 08/06/2023 |
| Opportunities for engineering Outer Membrane Vesicles (OMVs) using synthetic biology approaches | Extracellular Vesicles and Circulating Nucleic Acids | Article | Kelwick R, Webb A, Freemont P | 15/07/1905 |
| Particular genomic and virulence traits associated with preterm infant-derived toxigenic Clostridium perfringens strains. | Nature Microbiology | Journal Article, Research Support, Non-U.S. Gov’t | Kiu R, Shaw AG, Sim K, Acuna-Gonzalez A, Price CA, Bedwell H, Dreger SA, Fowler WJ, Cornwell E, Pickard D, Belteki G, Malsom J, Phillips S, Young GR, Schofield Z, Alcon-Giner C, Berrington JE, Stewart CJ, Dougan G, Clarke P, Douce G, Robinson SD, Kroll JS, Hall LJ | 01/06/2023 |
| Phage-Inducible Chromosomal Islands as a Diagnostic Platform to Capture and Detect Bacterial Pathogens. | Advanced Science | Journal Article | Ibarra-Chávez R, Reboud J, Penadés JR, Cooper JM | 26/06/2023 |
| Phosphoregulation of DNA repair via the Rad51 auxiliary factor Swi5-Sfr1. | Journal of Biological Chemistry | Journal Article | Liang P, Lister K, Yates L, Argunhan B, Zhang X | 15/06/2023 |
| Politicization of water, humanitarian response, and health in Syria as a contributor to the ongoing cholera outbreak. | International Journal of Infectious Diseases | Journal Article | Tarnas MC, Karah N, Almhawish N, Aladhan I, Alobaid R, Abbara A | 01/06/2023 |
| Practical considerations for a TB controlled human infection model (TB-CHIM); the case for TB-CHIM in Africa, a systematic review of the literature and report of 2 workshop discussions in UK and Malawi. | Wellcome Open Research | Systematic Review | Gordon SB, Sichone S, Chirwa AE, Hazenberg P, Kafuko Z, Ferreira DM, Flynn J, Fortune S, Balasingam S, Biagini GA, McShane H, Mwandumba HC, Jambo K, Dedha K, Raj Sharma N, Robertson BD, Walker NF, Morton B, TB Controlled Human Infection Model Development Group | 15/07/1905 |
| Publisher Correction: DNA synthesis technologies to close the gene writing gap. | Nature Reviews Chemistry | Published Erratum | Hoose A, Vellacott R, Storch M, Freemont PS, Ryadnov MG | 30/06/2023 |
| Quantitative trait and transcriptome analysis of genetic complexity underpinning cardiac interatrial septation in mice using an advanced intercross line | eLife | Journal article | Moradi Marjaneh M, Kirk EP, Patrick R, Alankarage D, Humphreys DT, Del Monte-Nieto G, Cornejo-Paramo P, Janbandhu V, Doan TB, Dunwoodie SL, Wong ES, Moran C, Martin ICA, Thomson PC, Harvey RP | 05/06/2023 |
| Rapid Diagnostic Test Value and Implementation in Antimicrobial Stewardship Across Low-to-Middle and High-Income Countries: A Mixed-Methods Review. | Infectious Diseases and Therapy | Journal Article | Moore LSP, Villegas MV, Wenzler E, Rawson TM, Oladele RO, Doi Y, Apisarnthanarak A | 01/06/2023 |
| Ready, STAT3, Go! Bacteria in the race for M2 macrophage polarisation. | Current Opinion in Microbiology | Journal Article, Review, Research Support, Non-U.S. Gov’t | Panagi I, Thurston TL | 01/06/2023 |
| Redirected vaccine imprinting by co-administration of COVID-19 and influenza vaccines. | The Lancet Regional Health. Europe | Journal Article | Boyton RJ, Altmann DM | 01/06/2023 |
| Risk factors and vectors for SARS-CoV-2 household transmission: a prospective, longitudinal cohort study. | The Lancet Microbe | Journal Article, Research Support, Non-U.S. Gov’t | Derqui N, Koycheva A, Zhou J, Pillay TD, Crone MA, Hakki S, Fenn J, Kundu R, Varro R, Conibear E, Madon KJ, Barnett JL, Houston H, Singanayagam A, Narean JS, Tolosa-Wright MR, Mosscrop L, Rosadas C, Watber P, Anderson C, Parker E, Freemont PS, Ferguson NM, Zambon M, McClure MO, Tedder R, Barclay WS, Dunning J, Taylor GP, Lalvani A, INSTINCT and ATACCC study group | 01/06/2023 |
| SARS-CoV-2 infection and pulmonary tuberculosis in children and adolescents: a case-control study | BMC Infectious Diseases | Article | Swanepoel J, van der Zalm MM, Preiser W, van Zyl G, Whittaker E, Hesseling AC, Moore DAJ, Seddon J | 29/06/2023 |
| Sensitive Detection of Asymptomatic and Symptomatic Malaria with Seven Novel Parasite-Specific LAMP Assays and Translation for Use at Point-of-Care. | Microbiology Spectrum | Journal Article | Malpartida-Cardenas K, Moser N, Ansah F, Pennisi I, Ahu Prah D, Amoah LE, Awandare G, Hafalla JCR, Cunnington A, Baum J, Rodriguez-Manzano J, Georgiou P | 15/06/2023 |
| Speaking the host language: how Salmonella effector proteins manipulate the host. | Microbiology | Review, Journal Article, Research Support, Non-U.S. Gov’t | Pillay TD, Hettiarachchi SU, Gan J, Diaz-Del-Olmo I, Yu X-J, Muench JH, Thurston TLM, Pearson JS | 01/06/2023 |
| The omission of children from the UK’s antimicrobial strategy must be tackled. | BMJ: British Medical Journal | Editorial | Channon-Wells S, Patel S | 22/06/2023 |
| Triplex qPCR assay for Campylobacter jejuni and Campylobacter coli monitoring in wastewater. | Science of the Total Environment | Journal Article | Zhang S, Shi J, Li X, Luby S, Coin L, O’Brien JW, Sivakumar M, Hai F, Jiang G | 01/06/2023 |
| Understanding how diagnostics influence antimicrobial decision-making is key to successful clinical trial design. | Clinical Microbiology and Infection | Journal Article, Comment | Rawson TM, Moore LSP | 01/06/2023 |
| Use of cidofovir in a patient with severe mpox and uncontrolled HIV infection. | Lancet Infectious Diseases | Case Reports, Journal Article, Review, Research Support, Non-U.S. Gov’t | Stafford A, Rimmer S, Gilchrist M, Sun K, Davies EP, Waddington CS, Chiu C, Armstrong-James D, Swaine T, Davies F, Gómez CHM, Kumar V, ElHaddad A, Awad Z, Smart C, Mora-Peris B, Muir D, Randell P, Peters J, Chand M, Warrell CE, Rampling T, Cooke G, Dhanji S, Campbell V, Davies C, Osman S, Abbara A | 01/06/2023 |
| Viral emissions into the air and environment after SARS-CoV-2 human challenge: a phase 1, open label, first-in-human study. | The Lancet Microbe | Journal Article | Zhou J, Singanayagam A, Goonawardane N, Moshe M, Sweeney FP, Sukhova K, Killingley B, Kalinova M, Mann AJ, Catchpole AP, Barer MR, Ferguson NM, Chiu C, Barclay WS | 09/06/2023 |
| Yemen: current peace talks must also prioritise health. | BMJ: British Medical Journal | Editorial | Attal B, Dureab F, Abbara A | 05/06/2023 |
| Increasing human monoclonal antibody cloning efficiency with a whole-cell modified immunoglobulin-capture assay (mICA) | Frontiers in Immunology | Journal Article | Siris S, Gladstone CA, Guo Y, Patel R, Pinder CL, Shattock RJ, McKay PF, Langford PR and Bidmos FA | 02/06/2023 |
| The immunology of long COVID. | Nature Reviews Immunology | Journal Article | Altmann DM, Whettlock EM, Liu S | 11/07/2023 |