Latest publications: September 2023


Congratulations to members of the Department who have recently had their research findings published. Here’s our round-up of the latest publication successes.

To ensure the quality and accuracy of the information published on this blog, we source our data directly from Symplectic. Our reports are generated on a monthly basis, which means there may be a delay in publicising some publications.

Title Canonical journal title Publication type Authors OR Authors/Contributors Publication date
A 3D-printed flow-cell for on-grid purification of electron microscopy samples directly from lysate Journal of Structural Biology Journal article Ramlaul K, Feng Z, Canavan C, Garrido NDM, Carreno D, Crone M, Jensen KE, Li B, Barnett H, Riglar DT, Freemont PS, Miller D, Aylett CHS 01/09/2023
A CRISPR-Cas12a-based platform facilitates the detection and serotyping of Streptococcus suis serotype 2. Talanta Journal Article Wang L, Sun J, Zhao J, Bai J, Zhang Y, Zhu Y, Zhang W, Wang C, Langford PR, Liu S, Li G 16/09/2023
A molnupiravir-associated mutational signature in global SARS-CoV-2 genomes. Nature Journal Article Sanderson T, Hisner R, Donovan-Banfield I, Hartman H, Løchen A, Peacock TP, Ruis C 25/09/2023
Assembly mechanism of a Tad secretion system secretin-pilotin complex. Nature Communications Journal Article Tassinari M, Rudzite M, Filloux A, Low HH 13/09/2023
Asymptomatic Plasmodium falciparum infection evades triggering a host transcriptomic response Journal of Infection Letter, Journal Prah DA, Dunican C, Amoah LE, Marjaneh MM, Kaforou M, Nordgren A, Jones-Warner W, Aniweh Y, Awandare GA, Cunnington AJ, Hafalla JC 01/09/2023
Author Correction: The immunology of long COVID. Nature Reviews Immunology Published Erratum Altmann DM, Whettlock EM, Liu S, Arachchillage DJ, Boyton RJ 18/09/2023
AWaRe-ness of antimicrobial stewardship challenges in pediatric emergency care: results from the PERFORM study assessing consistency and appropriateness of antibiotic prescribing across Europe Clinical Infectious Diseases Journal article Kolberg L, Khanijau A, van der Velden F, Herberg J, De T, Galassini R, Cunnington A, Wright V, Shah P, Kaforou M, Wilson C, Kuijpers T, Martinón-Torres F, Rivero-Calle I, Moll H, Vermont C, Pokorn M, Kolnik M, Pollard A, Agyeman P, Schlapbach L, Tsolia M, Yeung S, Zavadska D, Zenz W, Schweintzger N, Van Der Flier M, de Groot R, Usuf E, Voice M, Calvo-Bado L, Mallet F, Fidler K, Levin M, Carrol E, Emonts M, von Both U, The PERFORM Consortium 11/10/2023
Cardiopulmonary resuscitation in low-resource settings: a statement by the International Liaison Committee on Resuscitation, supported by the AFEM, EUSEM, IFEM, and IFRC. The Lancet Global Health Journal Article, Review Schnaubelt S, Garg R, Atiq H, Baig N, Bernardino M, Bigham B, Dickson S, Geduld H, Al-Hilali Z, Karki S, Lahri S, Maconochie I, Montealegre F, Tageldin Mustafa M, Niermeyer S, Athieno Odakha J, Perlman JM, Monsieurs KG, Greif R, Cardiopulmonary Resuscitation in Low-Resource Settings Group 01/09/2023
Conserved structures of ESCRT-III superfamily members across domains of life. Trends in Biochemical Sciences Journal Article, Review Schlösser L, Sachse C, Low HH, Schneider D 15/09/2023
Defining drivers of under-immunization and vaccine hesitancy in refugee and migrant populations Journal of Travel Medicine Review, Early Access, Journal Deal A, Crawshaw AF, Carter J, Knights F, Iwami M, Darwish M, Hossain R, Immordino P, Kaojaroen K, Severoni S, Hargreaves S 05/09/2023
Derivation of a high-resolution CT-based, semi-automated radiographic score in tuberculosis and its relationship to bacillary load and antitubercular therapy. European Respiratory Journal Letter Riou C, du Bruyn E, Kim GHJ, da Costa I, Lee J, Sher A, Wilkinson RJ, Allwood BW, Goldin J 07/09/2023
Design and Implementation of a National Program to Monitor the Prevalence of SARS-CoV-2 IgG Antibodies in England Using Self-Testing: The REACT-2 Study. American Journal of Public Health Journal Article Ward H, Atchison C, Whitaker M, Davies B, Ashby D, Darzi A, Chadeau-Hyam M, Riley S, Donnelly CA, Barclay W, Cooke GS, Elliott P 21/09/2023
Diagnosis of childhood febrile illness using a multi-class blood RNA molecular signature. Med Journal Article Habgood-Coote D, Wilson C, Shimizu C, Barendregt AM, Philipsen R, Galassini R, Calle IR, Workman L, Agyeman PKA, Ferwerda G, Anderson ST, van den Berg JM, Emonts M, Carrol ED, Fink CG, de Groot R, Hibberd ML, Kanegaye J, Nicol MP, Paulus S, Pollard AJ, Salas A, Secka F, Schlapbach LJ, Tremoulet AH, Walther M, Zenz W, Pediatric Emergency Medicine Kawasaki Disease Research Group (PEMKDRG), UK Kawasaki Genetics consortium, GENDRES consortium, EUCLIDS consortium, PERFORM consortium, Van der Flier M, Zar HJ, Kuijpers T, Burns JC, Martinón-Torres F, Wright VJ, Coin LJM, Cunnington AJ, Herberg JA, Levin M, Kaforou M 08/09/2023
Digerati-A multipath parallel hybrid deep learning framework for the identification of mycobacterial PE/PPE proteins Computers in Biology and Medicine Journal Article Li F, Guo X, Bi Y, Jia R, Pitt ME, Pan S, Li S, Gasser RB, Coin LJM, Song J 01/09/2023
Discrepancies in Management of Congenital Cytomegalovirus in Preterm Infants: An International Survey The Pediatric Infectious Disease Journal Journal Article Petrunin Y, Payne H, Blazquez-Gamero D, Buxmann H, Drysdale SB, Gkentzi D, Papaevangelou V, Lyall H 01/09/2023
DNA-directed termination of RNA polymerase II transcription. Molecular Cell Journal Article Han Z, Moore GA, Mitter R, Lopez Martinez D, Wan L, Dirac Svejstrup AB, Rueda DS, Svejstrup JQ 21/09/2023
Early evaluation of the safety, reactogenicity, and immune response after a single dose of modified vaccinia Ankara- Bavaria Nordic vaccine against mpox in children: a national outbreak response Lancet Infectious Diseases Journal Article Ladhani SN, Dowell AC, Jones S, Hicks B, Rowe C, Begum J, Wailblinger D, Wright J, Owens S, Pickering A, Shilltoe B, Mcmaster P, Whittaker E, Zuo J, Powell A, Amirthalingam G, Mandal S, Lopez-Bernal J, Ramsay ME, Kissane N, Bell M, Watson H, Ho D, Hallis B, Otter A, Moss P, Cohen J 01/09/2023
Effectiveness and resource utilization of hospital-based contact tracing of patients and health care workers with COVID-19 at a tertiary teaching hospital in Thailand Clinical Epidemiology and Global Health Journal Article Nasomsong W, Changpradub D, Vasikasin V 01/09/2023
Evaluating the cost implications of integrating SARS-CoV-2 genome sequencing for infection prevention and control investigation of nosocomial transmission within hospitals Journal of Hospital Infection Journal Article Panca M, Blackstone J, Stirrup O, Cutino-Moguel M-T, Thomson E, Peters C, Snell LB, Nebbia G, Holmes A, Chawla A, Machin N, Taha Y, Mahungu T, Saluja T, de Silva TI, Saeed K, Pope C, Shin GY, Williams R, Darby A, Smith DL, Loose M, Robson SC, Laing K, Partridge DG, Price JR, Breuer J 01/09/2023
Hepatic steatosis in people older and younger than fifty who are living with HIV and HIV-negative controls: A cross-sectional study nested within the POPPY cohort. HIV Medicine Journal Article Arenas-Pinto A, Bakewell N, Milinkovic A, Williams I, Vera J, Post FA, Anderson J, Beynon M, O’Brien A, Doyle N, Gilson R, Pett SL, Winston A, Sabin CA, Pharmacokinetic and clinical Observations in People over fiftY [POPPY]) study 05/09/2023
HTLV infection and cessation of breastfeeding: context and challenges in implementing universal prevention policies in Brazil. Epidemiologia e Serviços de Saúde Journal Article Rosadas C, Miranda AE 18/09/2023
HTLV-1 screening of blood donations: We are systematically missing opportunities British Journal of Haematology Letter, Early Access, Journal Rosadas C, Harvala H, Davison K, Taylor GP 01/09/2023
Human cytomegalovirus immunoglobulin G response and pulmonary tuberculosis in adolescents: a case-control study Open Forum Infectious Diseases Journal Article Swanepoel J, van Zyl G, Hesseling A, Johnson S, Moore D, Seddon J 29/09/2023
Humoral and cellular responses to SARS-CoV-2 in patients with B-cell haematological malignancies improve with successive vaccination. British Journal of Haematology Journal Article, Research Support, Non-U.S. Gov’t Pinder CL, Jankovic D, Fox TA, Kirkwood A, Enfield L, Alrubayyi A, Touizer E, Ford R, Pocock R, Shin J-S, Ziegler J, Thomson KJ, Ardeshna KM, Peppa D, McCoy LE, Morris EC 01/09/2023
Impact of the COVID-19 pandemic on antimicrobial stewardship support for general practices in England: a qualitative interview study. BJGP Open Journal Article Campbell A, Borek AJ, McLeod M, Tonkin-Crine S, Pouwels KB, Roope LS, Hayhoe BW, Majeed A, Walker AS, Holmes A, STEP-UP team 01/09/2023
Impact of the Syrian conflict and forced displacement on respiratory health: an analysis of primary data from a humanitarian organisation BMJ Open Respiratory Research Article, Journal Basha L, Socarras A, Akhter MW, Hamze M, Albaik A, Hussein I, Tarakji A, Hamadeh M, Loutfi R, Kewara M, Abbara A 01/09/2023
Increased reports of severe myocarditis associated with enterovirus infection in neonates, United Kingdom, 27 June 2022 to 26 April 2023 Eurosurveillance Journal Article Singanayagam A, Moore C, Froude S, Celma C, Stowe J, Hani E, Ng KF, Muir P, Roderick M, Cottrell S, Bibby DF, Vipond B, Gillett S, Davis PJ, Gibb J, Barry M, Harris P, Rowley F, Song J, Shankar AG, McMichael D, Cohen JM, Manian A, Harvey C, Primrose LS, Wilson S, Bradley DT, Paranthaman K, Beard S, Zambon M, Ramsay M, Saliba V, Ladhani S, Williams C 28/09/2023
IS1-related large-scale deletion of chromosomal regions harbouring the oxygen-insensitive nitroreductase gene nfsB causes nitrofurantoin heteroresistance in Escherichia coli. Microbial Genomics Journal Article, Research Support, Non-U.S. Gov’t Wan Y, Sabnis A, Mumin Z, Potterill I, Jauneikaite E, Brown CS, Ellington MJ, Edwards A, Sriskandan S 01/09/2023
LION: Taming RNA vaccine inflammation. Molecular Therapy Editorial Tregoning JS 06/09/2023
Liver injury in hospitalized patients with COVID-19: An International observational cohort study. PLoS One Observational Study, Journal Article, Research Support, Non-U.S. Gov’t Tirupakuzhi Vijayaraghavan BK, Bishnu S, Baruch J, Citarella BW, Kartsonaki C, Meeyai A, Mohamed Z, Ohshimo S, Lefèvre B, Al-Fares A, Calvache JA, Taccone FS, Olliaro P, Merson L, Adhikari NKJ, ISARIC Clinical Characterisation Group 13/09/2023
Multisystem inflammatory syndrome in children: a longitudinal perspective on risk factors and future directions. Pediatric Research Journal Article Patel H, Burgner D, Whittaker E 04/09/2023
Neutralising antibody responses against SARS-CoV-2 Omicron BA.4/5 and wild-type virus in patients with inflammatory bowel disease following three doses of COVID-19 vaccine (VIP): a prospective, multicentre, cohort study EClinicalMedicine Article Liu Z, Alexander J, Le K, Zhou X, Ibraheim H, Anandabaskaran S, Saifuddin M, LIN K, Leon M, Constable L, Castro Seoane R, Anand N, Bewshea C, Nice R, D’Mello A, Jones G, Balarajah S, Fiorentino F, Sebastian S, Irving P, Hicks LC, Williams HRT, Kent A, Linger R, Parkes M, Klaartje K, Patel K, Teare JP, Altmann DM, Boyton RJ, Hart AL, Lees C, Goodhand J, Kennedy N, Pollock K, Ahmad T, Powell N 05/10/2023
Outsourcing covid-19 vaccination to the private sector will increase health inequalities. BMJ: British Medical Journal Editorial Altmann DM, Boyton RJ 04/09/2023
Phosphoregulation of the checkpoint kinase Mec1ATR DNA Repair Article, Journal Yates LA, Zhang X 01/09/2023
Policy versus practice: Syrian refugee doctors in Egypt. Medicine, Conflict and Survival Journal Article Ghobrial A, Sabouni A, Rayes D, Janoudi S, Bdaiwi Y, Howard N, Abbara A 01/09/2023
Relationship between molecular pathogen detection and clinical disease in febrile children across Europe: a multicentre, prospective observational study. The Lancet Regional Health. Europe Journal Article Shah P, Voice M, Calvo-Bado L, Rivero-Calle I, Morris S, Nijman R, Broderick C, De T, Eleftheriou I, Galassini R, Khanijau A, Kolberg L, Kolnik M, Rudzate A, Sagmeister MG, Schweintzger NA, Secka F, Thakker C, van der Velden F, Vermont C, Vincek K, Agyeman PKA, Cunnington AJ, De Groot R, Emonts M, Fidler K, Kuijpers TW, Mommert-Tripon M, Brengel-Pesce K, Mallet F, Moll H, Paulus S, Pokorn M, Pollard A, Schlapbach LJ, Shen C-F, Tsolia M, Usuf E, van der Flier M, von Both U, Yeung S, Zavadska D, Zenz W, Wright V, Carrol ED, Kaforou M, Martinon-Torres F, Fink C, Levin M, Herberg J, PERFORM consortium 01/09/2023
Safety of Streptococcus pyogenes Vaccines: Anticipating and Overcoming Challenges for Clinical Trials and Post-Marketing Monitoring. Clinical Infectious Diseases Journal Article, Research Support, Non-U.S. Gov’t Asturias EJ, Excler J-L, Ackland J, Cavaleri M, Fulurija A, Long R, McCulloch M, Sriskandan S, Sun W, Zühlke L, Kim JH, Dale JB, Steer AC 18/09/2023
Smart-Plexer: a breakthrough workflow for hybrid development of multiplex PCR assays. Communications Biology Journal Article, Research Support, Non-U.S. Gov’t Miglietta L, Chen Y, Luo Z, Xu K, Ding N, Peng T, Moniri A, Kreitmann L, Cacho-Soblechero M, Holmes A, Georgiou P, Rodriguez-Manzano J 09/09/2023
Symbiotic Firmicutes establish mutualism with the host via innate tolerance and resistance to control systemic immunity. Cell Host and Microbe Journal Article Jordan CKI, Brown RL, Larkinson MLY, Sequeira RP, Edwards AM, Clarke TB 13/09/2023
The Challenge Non-Typhoidal Salmonella (CHANTS) Consortium: Development of a non-typhoidal Salmonella controlled human infection model: Report from a consultation group workshop, 05 July 2022, London, UK Wellcome Open Research Journal Article Smith C, Smith E, Chiu C, Hinton J, Perez Sepulveda B, Gordon M, Choy RKM, Hill PWS, Meiring JE, Darton TC, Carey ME, Cooke G, Gibani MM 21/09/2023
The effect of universal testing and treatment for HIV on health-related quality of life – An analysis of data from the HPTN 071 (PopART) cluster randomised trial SSM: Population Health Journal Article Davis K, Pickles M, Gregson S, Hargreaves JR, Ayles H, Bock P, Pliakas T, Thomas R, Ohrnberger J, Bwalya J, Bell-Mandla N, Shanaube K, Probert W, Hoddinott G, Bond V, Hayes R, Fidler S, Hauck K 01/09/2023
The threat of antimicrobial resistance in surgical care: the surgeon’s role and ownership of antimicrobial stewardship British Journal of Surgery Article Birgand G, Holmes A 27/09/2023
Treatment of tuberculous meningitis: Overdue for concerted action. Tuberculosis Journal Article, Research Support, Non-U.S. Gov’t, Research Support, N.I.H., Extramural Wilkinson RJ, Donovan J, Thwaites GE, van Crevel R, Wasserman S 01/09/2023
Triplex qPCR assay for Campylobacter jejuni and Campylobacter coli monitoring in wastewater Science of the Total Environment Journal Article Zhang S, Shi J, Li X, Coin L, O’Brien JW, Sivakumar M, Hai F, Jiang G 20/09/2023
Tuberculosis prevalence after 4 years of population-wide systematic TB symptom screening and universal testing and treatment for HIV in the HPTN 071 (PopART) community-randomised trial in Zambia and South Africa: A cross-sectional survey (TREATS). PLoS Medicine Randomized Controlled Trial, Journal Article Klinkenberg E, Floyd S, Shanaube K, Mureithi L, Gachie T, de Haas P, Kosloff B, Dodd PJ, Ruperez M, Wapamesa C, Burnett JM, Kalisvaart N, Kasese N, Vermaak R, Schaap A, Fidler S, Hayes R, Ayles H, TREATS study team 01/09/2023
Vitamin D supplementation to prevent tuberculosis infection in South African schoolchildren: multicenter phase 3 double-blind randomized placebo-controlled trial (ViDiKids) International Journal of Infectious Diseases Journal Article Middelkoop K, Stewart J, Walker N, Delport C, Jolliffe DA, Coussens AK, Nuttall J, Tang JCY, Fraser WD, Griffiths CJ, Kumar GT, Filteau S, Hooper RL, Wilkinson RJ, Bekker L-G, Martineau AR 01/09/2023
What does SARS-CoV-2 tell us about the aetiology of environmental triggers for diabetes in children and young people? Acta Paediatrica: promoting child health Editorial Material, Early Access, Journal Ponmani C, Lyttle MD, Barrett M, Hulse T, Nijman RG, Roland D, DIMPLES SG 11/09/2023