Congratulations to members of the Department who have recently had their research findings published. Here’s our round-up of the latest publication successes.
To ensure the quality and accuracy of the information published on this blog, we source our data directly from Symplectic. Our reports are generated on a monthly basis, which means there may be a delay in publicising some publications.
| Title | Canonical journal title | Publication Type | Authors OR Authors/Contributors | Publication date |
| A molnupiravir-associated mutational signature in global SARS-CoV-2 genomes. | Nature | Journal Article | Sanderson T, Hisner R, Donovan-Banfield I, Hartman H, Løchen A, Peacock TP, Ruis C | 01/11/2023 |
| A multi-platform approach to identify a blood-based host protein signature for distinguishing between bacterial and viral infections in febrile children (PERFORM): a multi-cohort machine learning study. | The Lancet: Digital Health | Journal Article, Research Support, Non-U.S. Gov’t | Jackson HR, Zandstra J, Menikou S, Hamilton MS, McArdle AJ, Fischer R, Thorne AM, Huang H, Tanck MW, Jansen MH, De T, Agyeman PKA, Von Both U, Carrol ED, Emonts M, Eleftheriou I, Van der Flier M, Fink C, Gloerich J, De Groot R, Moll HA, Pokorn M, Pollard AJ, Schlapbach LJ, Tsolia MN, Usuf E, Wright VJ, Yeung S, Zavadska D, Zenz W, Coin LJM, Casals-Pascual C, Cunnington AJ, Martinon-Torres F, Herberg JA, de Jonge MI, Levin M, Kuijpers TW, Kaforou M, PERFORM consortium | 01/11/2023 |
| A preclinical model of TB meningitis to determine drug penetration and activity at the sites of disease. | Antimicrobial Agents and Chemotherapy | Journal Article | Lanni F, Antilus Sainte R, Hansen M, Parigi P, Kaya F, LoMauro K, Siow B, Wilkinson RJ, Wasserman S, Podell BK, Gengenbacher M, Dartois V | 15/11/2023 |
| Antibody responses to Influenza vaccination are diminished in patients with inflammatory bowel disease on infliximab or tofacitinib. | Journal of Crohn’s and Colitis | Journal Article | Liu Z, Alexander JL, Eng KY, Ibraheim H, Anandabaskaran S, Saifuddin A, Constable L, Seoane RC, Bewshea C, Nice R, D’Mello A, Jones GR, Balarajah S, Fiorentino F, Sebastian S, Irving PM, Hicks LC, Williams HRT, Kent AJ, Linger R, Parkes M, Kok K, Patel KV, Teare JP, Altmann DM, Boyton RJ, Hart AL, Lees CW, Goodhand JR, Kennedy NA, Pollock KM, Ahmad T, Powell N, VIP study investigators | 06/11/2023 |
| ATG9B is a tissue-specific homotrimeric lipid scramblase that can compensate for ATG9A. | Autophagy | Journal Article | Chiduza GN, Garza-Garcia A, Almacellas E, De Tito S, Pye VE, van Vliet AR, Cherepanov P, Tooze SA | 08/11/2023 |
| Attacks on health are war crimes and a public health catastrophe. | The Lancet | Letter | Haar R, Abbara A, Rubenstein L, Spiegel P, Alnahhas H | 25/11/2023 |
| Communicable diseases in northwest Syria in the context of protracted armed conflict and earthquakes. | Lancet Infectious Diseases | Journal Article, Review | Tarnas MC, Almhawish N, Karah N, Sullivan R, Abbara A | 01/11/2023 |
| Conserved structures of ESCRT-III superfamily members across domains of life. | Trends in Biochemical Sciences | Journal Article, Review | Schlösser L, Sachse C, Low HH, Schneider D | 01/11/2023 |
| Conversational Agents in Health Care: Expert Interviews to Inform the Definition, Classification, and Conceptual Framework. | Journal of Medical Internet Research | Journal Article, Research Support, Non-U.S. Gov’t | Martinengo L, Lin X, Jabir AI, Kowatsch T, Atun R, Car J, Tudor Car L | 01/11/2023 |
| Design and Implementation of a National Program to Monitor the Prevalence of SARS-CoV-2 IgG Antibodies in England Using Self-Testing: The REACT-2 Study. | American Journal of Public Health | Journal Article, Research Support, Non-U.S. Gov’t | Ward H, Atchison C, Whitaker M, Davies B, Ashby D, Darzi A, Chadeau-Hyam M, Riley S, Donnelly CA, Barclay W, Cooke GS, Elliott P | 01/11/2023 |
| DLL4-Notch3-WNT5B axis mediates bi-directional pro-metastatic crosstalk between melanoma and lymphatic endothelial cells. | JCI Insight | Journal Article | Alve S, Gramolelli S, Jukonen J, Juteau S, Pink A, Manninen AA, Hänninen S, Monto E, Lackman MH, Carpén O, Saharinen P, Karaman S, Vaahtomeri K, Ojala PM | 16/11/2023 |
| Early mucosal events promote distinct mucosal and systemic antibody responses to live attenuated influenza vaccine. | Nature Communications | Journal Article | Thwaites RS, Uruchurtu ASS, Negri VA, Cole ME, Singh N, Poshai N, Jackson D, Hoschler K, Baker T, Scott IC, Ros XR, Cohen ES, Zambon M, Pollock KM, Hansel TT, Openshaw PJM | 05/12/2023 |
| Efficacy and Safety of Glycosphingolipid SSEA-4 Targeting CAR-T Cells in an Ovarian Carcinoma Model. | Molecular Cancer Therapeutics | Journal Article | Monzo HJ, Kalander K, Hyytiäinen MM, Elbasani E, Wall J, Moyano-Galceran L, Tanjore Ramanathan J, Jukonen J, Laakkonen P, Ristimäki A, Carlson JW, Lehti K, Salehi S, Puolakkainen P, Haglund C, Seppänen H, Leppä S, Ojala PM | 01/11/2023 |
| Efficacy of Fowlpox Virus Vector Vaccine Expressing VP2 and Chicken Interleukin-18 in the Protection against Infectious Bursal Disease Virus. | Vaccines | Journal Article | Eldaghayes I, Rothwell L, Skinner M, Dayhum A, Kaiser P | 14/11/2023 |
| Enhancing the antibacterial function of probiotic Escherichia coli Nissle: when less is more. | Applied and Environmental Microbiology | Journal Article | Bartram E, Asai M, Gabant P, Wigneshweraraj S | 29/11/2023 |
| Environmental factors of food insecurity in adolescents: A scoping review protocol. | PLoS One | Journal Article | Capitán-Moyano L, Cañellas-Iniesta N, Arias-Fernández M, Bennasar-Veny M, Yáñez AM, Castro-Sánchez E | 21/11/2023 |
| European expert recommendations on clinical investigation and evaluation of high-risk medical devices for children | Acta Paediatrica: promoting child health | Article, Early Access, Journal | Guerlich K, Patro-Golab B, Barnacle A, Baumann U, Eicken AG, Fraser A, Gruszfeld DA, Haas NH, Jonker A, Kammermeier M, Kenny D, Kolacek S, Lapatto R, Maconochie I, Mader S, McGauran G, Melvin T, Muensterer O, Piscoi P, Romano AK, Saxena AT, Schneider DA, Turner M, Vande Walle J, Koletzko B, European AP | 01/11/2023 |
| Experiences of initiating rapid antiretroviral therapy among people newly diagnosed with HIV in East London: a qualitative study | Sexually Transmitted Infections | Article, Early Access, Journal | Dhairyawan R, Milner A, Thornhill JP, Kwardem L, Matin N, Orkin C, Deane K | 01/11/2023 |
| Genomics for public health and international surveillance of antimicrobial resistance. | The Lancet Microbe | Journal Article, Review | Baker KS, Jauneikaite E, Hopkins KL, Lo SW, Sánchez-Busó L, Getino M, Howden BP, Holt KE, Musila LA, Hendriksen RS, Amoako DG, Aanensen DM, Okeke IN, Egyir B, Nunn JG, Midega JT, Feasey NA, Peacock SJ, SEDRIC Genomics Surveillance Working Group | 14/11/2023 |
| Guiding pragmatic treatment choices for rifampicin-resistant tuberculosis in the absence of second-line drug susceptibility testing. | European Respiratory Journal | Letter | Achar J, Seddon JA, Knight GM, Dodd PJ, Esmail H, Hughes J, McQuaid CF | 09/11/2023 |
| HTLV-1 as a contributing factor towards scabies and its systemic sequelae. | Journal of Global Health | Journal Article, Research Support, Non-U.S. Gov’t | Cockbain B, Rosadas C, Taylor GP | 03/11/2023 |
| Human Cytomegalovirus Immunoglobulin G Response and Pulmonary Tuberculosis in Adolescents: A Case-Control Study. | Open Forum Infectious Diseases | Journal Article | Swanepoel J, van Zyl G, Hesseling AC, Johnson SM, Moore DAJ, Seddon JA | 01/11/2023 |
| Identification of novel small RNAs in extracellular vesicles produced by Actinobacillus pleuropneumoniae | Frontiers in Microbiology | Article | da Silva GC, Rosa J, de Castro A, Barbosa E, Clarindo W, Mantovani H, Li Y, Bosse J, Langford P, Bazzolli D | 23/11/2023 |
| Is it possible to generalise superspreading individuals or events of SARS-CoV-2? – Authors’ reply. | The Lancet Microbe | Letter | Zhou J, Singanayagam A, Barclay WS | 01/11/2023 |
| Macromolecular condensation buffers intracellular water potential. | Nature | Journal Article | Watson JL, Seinkmane E, Styles CT, Mihut A, Krüger LK, McNally KE, Planelles-Herrero VJ, Dudek M, McCall PM, Barbiero S, Vanden Oever M, Peak-Chew SY, Porebski BT, Zeng A, Rzechorzek NM, Wong DCS, Beale AD, Stangherlin A, Riggi M, Iwasa J, Morf J, Miliotis C, Guna A, Inglis AJ, Brugués J, Voorhees RM, Chambers JE, Meng Q-J, O’Neill JS, Edgar RS, Derivery E | 01/11/2023 |
| Major revision version 12.0 of the European AIDS Clinical Society guidelines 2023. | HIV Medicine | Journal Article | Ambrosioni J, Levi L, Alagaratnam J, Van Bremen K, Mastrangelo A, Waalewijn H, Molina J-M, Guaraldi G, Winston A, Boesecke C, Cinque P, Bamford A, Calmy A, Marzolini C, Martínez E, Oprea C, Welch S, Koval A, Mendao L, Rockstroh JK, EACS Governing Board | 01/11/2023 |
| Multiplexed detection of viral antigen and RNA using nanopore sensing and encoded molecular probes. | Nature Communications | Journal Article, Research Support, Non-U.S. Gov’t | Ren R, Cai S, Fang X, Wang X, Zhang Z, Damiani M, Hudlerova C, Rosa A, Hope J, Cook NJ, Gorelkin P, Erofeev A, Novak P, Badhan A, Crone M, Freemont P, Taylor GP, Tang L, Edwards C, Shevchuk A, Cherepanov P, Luo Z, Tan W, Korchev Y, Ivanov AP, Edel JB | 14/11/2023 |
| Omicron breakthrough infections in vaccinated or previously infected hamsters. | Proceedings of the National Academy of Sciences of USA | Journal Article | Zhou J, Sukhova K, Peacock TP, McKay PF, Brown JC, Frise R, Baillon L, Moshe M, Kugathasan R, Shattock RJ, Barclay WS | 07/11/2023 |
| Parvovirus B19 Induced Acute Severe Anaemia in a Well-Controlled HIV-positive Individual | Clinical Infection in Practice | Journal Article | Swaine T, Ahmad N, Abbara A, Mora-Peris B, Wickremasinghe M, Lambert C, Khan A, Randell P | 01/12/2023 |
| Patient Biochemistry and Treatment Need in Chronic Hepatitis B Virus Infection Across Three Continents: Retrospective Cross-Sectional Cohort Studies | Infectious Diseases and Therapy | Article, Early Access, Journal | Gillespie IAA, Barnes E, Wong ICK, Matthews PCC, Cooke GSS, Tipple C, Elston RCC, Liu Y, Smith DAA, Wang T, Davies J, Varnai KAA, Freeman O, Man KKC, Lau WCY, Glampson B, Meng X, Morais E, Liu S, Mercuri L, Boxall N, Jenner S, Kendrick S, Dong J, Theodore D | 01/11/2023 |
| Phenotyping the virulence of SARS-CoV-2 variants in hamsters by digital pathology and machine learning. | PLoS Pathogens | Journal Article | Meehan GR, Herder V, Allan J, Huang X, Kerr K, Mendonca DC, Ilia G, Wright DW, Nomikou K, Gu Q, Molina Arias S, Hansmann F, Hardas A, Attipa C, De Lorenzo G, Cowton V, Upfold N, Palmalux N, Brown JC, Barclay WS, Filipe ADS, Furnon W, Patel AH, Palmarini M | 01/11/2023 |
| Poly(2-oxazoline)/saRNA Polyplexes for Targeted and Nonviral Gene Delivery | Biomacromolecules | Article, Early Access, Journal | Hayes G, Dias-Barbieri B, Yilmaz G, Shattock RJ, Becer CR | 04/10/2023 |
| Role of anaesthesia providers in infection-related care across the perioperative pathway: a global survey. | British Journal of Anaesthesia | Letter | Birgand G, Biccard B, Deslandes A, Mbamalu O, Bonaconsa C, Boutall A, Mendelson M, Leone M, Ndoli J, Leather A, Holmes A, Moonesinghe R, Charani E | 20/11/2023 |
| SARS-CoV-2 evolution in the Omicron era. | Nature Microbiology | Journal Article, Review | Roemer C, Sheward DJ, Hisner R, Gueli F, Sakaguchi H, Frohberg N, Schoenmakers J, Sato K, O’Toole Á, Rambaut A, Pybus OG, Ruis C, Murrell B, Peacock TP | 01/11/2023 |
| Serological evidence of virus infection in Eidolon helvum fruit bats: implications for bushmeat consumption in Nigeria | Frontiers in Public Health | Article | Giotis E | 27/11/2023 |
| Structure of a heteropolymeric type 4 pilus from a monoderm bacterium. | Nature Communications | Journal Article, Research Support, Non-U.S. Gov’t | Anger R, Pieulle L, Shahin M, Valette O, Le Guenno H, Kosta A, Pelicic V, Fronzes R | 06/11/2023 |
| Structure-activity studies of Streptococcus pyogenes enzyme SpyCEP reveal high affinity for CXCL8 in the SpyCEP C-terminal. | Scientific Reports | Journal Article, Research Support, Non-U.S. Gov’t | Pearson M, Haslam C, Fosberry A, Jones EJ, Reglinski M, Reeves L, Edwards RJ, Lawrenson RA, Brown JC, Mossakowska D, Pease JE, Sriskandan S | 03/11/2023 |
| The emerging art of doing less | Archives of Disease in Childhood | Journal Article | Nijman R, Cadman E, Maconochie I | 16/11/2023 |
| The protease associated (PA) domain in ScpA from Streptococcus pyogenes plays a role in substrate recruitment | BBA: Proteins and Proteomics | Article, Journal | Mckenna S, Aylward F, Miliara X, Lau RJ, Huemer CB, Giblin SP, Huse KK, Liang M, Reeves L, Pearson M, Xu Y, Rouse SL, Pease JE, Sriskandan S, Kagawa TF, Cooney J, Matthews S | 01/11/2023 |
| The threat of antimicrobial resistance in surgical care: the surgeon’s role and ownership of antimicrobial stewardship | British Journal of Surgery | Editorial Material, Early Access, Journal | Birgand G, Dhar P, Holmes A | 09/11/2023 |
| WHY STOP? A prospective observational vignette-based study to determine the cognitive-behavioural effects of rapid diagnostic PCR-based point-of-care test results on antibiotic cessation in ICU infections. | BMJ Open | Observational Study, Journal Article | Singh S, Nurek M, Mason S, Moore LS, Mughal N, Vizcaychipi MP | 21/11/2023 |