Latest publications: March 2024


Congratulations to members of the Department who have recently had their research findings published. Here’s our round-up of the latest publication successes.

To ensure the quality and accuracy of the information published on this blog, we source our data directly from Symplectic. Our reports are generated on a monthly basis, which means there may be a delay in publicising some publications.


Title Canonical journal title Publication Type Authors OR Authors/Contributors Publication date
Achievement of therapeutic antibiotic exposures using Bayesian dosing software in critically unwell children and adults with sepsis. Intensive Care Medicine Journal Article Chai MG, Tu Q, Cotta MO, Bauer MJ, Balch R, Okafor C, Comans T, Kruger P, Meyer J, Shekar K, Brady K, Fourie C, Sharp N, Vlad L, Whiley D, Ungerer JPJ, Mcwhinney BC, Farkas A, Paterson DL, Clark JE, Hajkowicz K, Raman S, Bialasiewicz S, Lipman J, Forde BM, Harris PNA, Schlapbach LJ, Coin L, Roberts JA, Irwin AD 13/03/2024
ATG9B is a tissue-specific homotrimeric lipid scramblase that can compensate for ATG9A. Autophagy Journal Article Chiduza GN, Garza-Garcia A, Almacellas E, De Tito S, Pye VE, van Vliet AR, Cherepanov P, Tooze SA 01/03/2024
Bacteriophages avoid autoimmunity from cognate immune systems as an intrinsic part of their life cycles. Nature Microbiology Journal Article Rostøl JT, Quiles-Puchalt N, Iturbe-Sanz P, Lasa Í, Penadés JR 02/04/2024
Cardiac Adverse Events and Remdesivir in Hospitalized Patients with Coronavirus Disease 2019 (COVID-19): A Post Hoc Safety Analysis of the Randomized DisCoVeRy Trial. Clinical Infectious Diseases Journal Article Terzić V, Miantezila Basilua J, Billard N, de Gastines L, Belhadi D, Fougerou-Leurent C, Peiffer-Smadja N, Mercier N, Delmas C, Ferrane A, Dechanet A, Poissy J, Espérou H, Ader F, Hites M, Andrejak C, Greil R, Paiva J-A, Staub T, Tacconelli E, Burdet C, Costagliola D, Mentré F, Yazdanpanah Y, Diallo A, DisCoVeRy study group 29/03/2024
Classification of early tuberculosis states to guide research for improved care and prevention: an international Delphi consensus exercise. The Lancet Respiratory Medicine Journal Article, Review Coussens AK, Zaidi SMA, Allwood BW, Dewan PK, Gray G, Kohli M, Kredo T, Marais BJ, Marks GB, Martinez L, Ruhwald M, Scriba TJ, Seddon JA, Tisile P, Warner DF, Wilkinson RJ, Esmail H, Houben RMGJ, International Consensus for Early TB (ICE-TB) group 22/03/2024
Comprehensive Insight into the Functional Roles of NK and NKT Cells in HTLV-1-Associated Diseases and Asymptomatic Carriers. Molecular Neurobiology Journal Article, Review Mahdifar M, Boostani R, Taylor GP, Rezaee SA, Rafatpanah H 04/03/2024
Correction for Gupta et al., “Bromo- and Extraterminal Domain Chromatin Regulators Serve as Cofactors for Murine Leukemia Virus Integration”. Journal of Virology Journal Article, Published Erratum Gupta SS, Maetzig T, Maertens GN, Sharif A, Rothe M, Weidner-Glunde M, Galla M, Schambach A, Cherepanov P, Schulz TF 13/03/2024
Cultural Adaption, Translation, Preliminary Reliability and Validity of Key Psychological and Behavioural Measures for 18 to 25 Year-Olds Living with HIV in Uganda: A Multi-Stage Approach. AIDS and Behavior Journal Article Evangeli M, Foster C, Musiime V, Fidler S, Seeley J, Frize G, Uwizera A, Price J 01/03/2024
Demographic characteristics and prevalence of asymptomatic Leishmania donovani infection in migrant workers working in an endemic area in Northwest Ethiopia Frontiers in Epidemiology Journal Article Yimer M, Takele Y, Yizengaw E, Nibret E, Sumova P Volf P, Tismaw G, Alehegn M, Rowan A, Müller I, Cotton A J, Chapman L A C, Kropf P 09/04/2024
Distinguishing community-acquired bacterial and viral meningitis: Microbes and biomarkers. Journal of Infection Journal Article, Review Ivaska L, Herberg J, Sadarangani M 01/03/2024
Evidence for immune activation in pathogenesis of the HLA class II associated disease, podoconiosis. Nature Communications Journal Article Negash M, Chanyalew M, Girma T, Alemu F, Alcantara D, Towler B, Davey G, Boyton RJ, Altmann DM, Howe R, Newport MJ 06/03/2024
Global Hfq-mediated RNA interactome of nitrogen starved Escherichia coli uncovers a conserved post-transcriptional regulatory axis required for optimal growth recovery. Nucleic Acids Research Journal Article McQuail J, Matera G, Gräfenhan T, Bischler T, Haberkant P, Stein F, Vogel J, Wigneshweraraj S 21/03/2024
Hospitalisation rates for youth living with perinatally acquired HIV in England. PLoS One Observational Study, Journal Article Johnson SM, Teh JJ, Pasvol TJ, Ayres S, Lyall H, Fidler S, Foster C 16/07/1905
Host gene expression signatures to identify infection type and organ dysfunction in children evaluated for sepsis: a multicentre cohort study. The Lancet Child & Adolescent Health Journal Article Schlapbach LJ, Ganesamoorthy D, Wilson C, Raman S, George S, Snelling PJ, Phillips N, Irwin A, Sharp N, Le Marsney R, Chavan A, Hempenstall A, Bialasiewicz S, MacDonald AD, Grimwood K, Cling JC, McPherson SJ, Blumenthal A, Kaforou M, Levin M, Herberg JA, Gibbons KS, Coin LJM, EUCLIDS consortium, RAPIDS Study Group 18/03/2024
Identification and management of co-infections in people with malaria. BMJ: British Medical Journal Journal Article Cunnington AJ, Abbara A, Bawa FK, Achan J 13/03/2024
Immunomodulatory therapy in children with paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS, MIS-C; RECOVERY): a randomised, controlled, open-label, platform trial. The Lancet Child & Adolescent Health Randomized Controlled Trial, Journal Article RECOVERY Collaborative Group 01/03/2024
In-hospital mortality during the wild-type, alpha, delta, and omicron SARS-CoV-2 waves: a multinational cohort study in the EuCARE project. The Lancet Regional Health. Europe Journal Article Hedberg P, Parczewski M, Serwin K, Marchetti G, Bai F, Ole Jensen B-E, Pereira JPV, Drobniewski F, Reschreiter H, Naumovas D, Ceccherini-Silberstein F, Rubio Quintanares GH, Mwau M, Toscano C, König F, Pfeifer N, Zazzi M, Fanti I, Incardona F, Cozzi-Lepri A, Sönnerborg A, Nauclér P 01/03/2024
Is the level of varicella-zoster virus IgG associated with symptomatic status of genital herpes simplex virus infection? A case-control study. International Journal of STD and AIDS Journal Article Palmer BS, Tang A, Winchester S, Atkins M, Barton S, Kelleher P 01/03/2024
Lessons from the pandemic: new best practices in selecting molecular diagnostics for point-of-care testing of infectious diseases in sub-Saharan Africa. Expert Review of Molecular Diagnostics: new diagnostic technologies are set to revolutionise healthcare Journal Article Baldeh M, Bawa FK, Bawah FU, Chamai M, Dzabeng F, Jebreel WMA, Kabuya J-BB, Molemodile Dele-Olowu SK, Odoyo E, Rakotomalala Robinson D, Cunnington AJ 01/03/2024
Long-term efficacy and safety of a treatment strategy for HIV infection using protease inhibitor monotherapy: 8-year routine clinical care follow-up from a randomised, controlled, open-label pragmatic trial (PIVOT) EClinicalMedicine Journal Article Paton NI, Stöhr W, Arenas-Pinto A, Clarke A, Williams I, Johnson M, Orkin C, Chen F, Lee V, Winston A, Gompels M, Fox J, Sanders K, Dunn DT, Fisher M, Clarke A, Hadley W, Stacey D, Johnson M, Byrne P, Williams I, De Esteban N, Pellegrino P, Haddow L, Arenas-Pinto A, Orkin C, Hand J, De Souza C, Murthen L, Crawford-Jones A, Chen F, Wilson R, Green E, Masterson J, Lee V, Patel K, Howe R, Winston A, Mullaney S, Gompels M, Jennings L, Beeching N, Tamaklo R, Fox J, Teague A, Jendrulek I, Tiraboschi JM, Wilkins E, Clowes Y, Thompson A, Brook G, Trivedi M, Aderogba K, Jones M, DeBurgh-Thomas A, Jones L, Reeves I, Mguni S, Chadwick D, Spence P, Nkhoma N, Warwick Z, Price S, Read S, Herieka E, Walker J, Woodward R, Day J, Hilton L, Harinda V, Blackman H, Hay P, Mejewska W, Okolo O, Ong E, Martin K, Munro L, Dockrell D, Smart L, Ainsworth J, Waters A, Kegg S, McNamara S, Taylor S, Gilleran G, Gazzard B, Rowlands J, Allan S, Sandhu R, O’Farrell N, Quaid S, Martin F, Bennett C, Kapembwa M, Minton J, Calderwood J, Post F, Campbell L, Wandolo E, Palfreeman A, Mashonganyika L, Balachandran T, Kakowa M, O’Connell R, Tanawa C, Jebakumar S, Hagger L, Quah S, McKernan S, Lacey C, Douglas S, Russell-Sharpe S, Brewer C, Leen C, Morris S, Obeyesekera S, Williams S, David N, Roberts M, Wollaston J, Paton N, Stöhr W, Arenas-Pinto A, Scott K, Dunn D, Beaumont E, Fleck S, Hall M, Hennings S, Kummeling I, Martins S, Owen-Powell E, Sanders K, van Hooff F, Vivas L, White E, Angus B, Freedman A, Cromerty B, Mercey D, Fidler S, Torok E, Babiker A, Gazzard B, Orkin C, Paton N, Peto T, Lalloo D, Phillips A, James R 01/03/2024
Molecular stripping underpins derepression of a toxin-antitoxin system. Nature Structural and Molecular Biology Journal Article Grabe GJ, Giorgio RT, Wieczór M, Gollan B, Sargen M, Orozco M, Hare SA, Helaine S 27/03/2024
Multidrug-resistant pathogens contaminate river water used in irrigation in disenfranchised communities. Journal of Global Antimicrobial Resistance Journal Article Osman M, Daaboul D, Tajani AG, El Omari K, Bisha B, Hassan J, Cazer CL, Fiorella KJ, Karah N, Abbara A, Hamze M, Cummings KJ, Naas T, Kassem II 01/03/2024
Novel antivirals for severe enterovirus infection in immunocompromised hosts; A case series. Journal of Infection Letter Meinhardt A, Reilly L, Kaliakatsos M, Abdel-Aziz K, Alsharidah S, Bodi I, Booth C, Chetty K, Evans J, Ferreras-Antolín L, Froude S, Galtrey CM, Guruprasad S, Hadden RD, Hassell J, Hyöty H, Kreins AY, Laiho JE, Lowe DM, Lunn MP, Mankad K, Struik S, Whittaker E, Worth A, Yong P, Zhang L, Breuer J, Kadambari S 26/03/2024
Outcomes of rheumatic fever in Uganda: a prospective cohort study. The Lancet Global Health Journal Article Wirth SH, Pulle J, Seo J, Ollberding NJ, Nakagaayi D, Sable C, Bowen AC, Parks T, Carapetis J, Okello E, Beaton A, Ndagire E 01/03/2024
PluMu—A Mu-like Bacteriophage Infecting Actinobacillus pleuropneumoniae Applied Microbiology Journal Article Bartsch LJ, Fernandez Crespo R, Wang Y, Skinner MA, Rycroft AN, Cooley W, Everest DJ, Li Y, Bossé JT, Langford PR 17/03/2024
Raising AWaRe-ness of Antimicrobial Stewardship Challenges in Pediatric Emergency Care: Results from the PERFORM Study Assessing Consistency and Appropriateness of Antibiotic Prescribing Across Europe. Clinical Infectious Diseases Journal Article, Research Support, Non-U.S. Gov’t Kolberg L, Khanijau A, van der Velden FJS, Herberg J, De T, Galassini R, Cunnington AJ, Wright VJ, Shah P, Kaforou M, Wilson C, Kuijpers T, Martinón-Torres F, Rivero-Calle I, Moll H, Vermont C, Pokorn M, Kolnik M, Pollard AJ, Agyeman PKA, Schlapbach LJ, Tsolia MN, Yeung S, Zavadska D, Zenz W, Schweintzger NA, van der Flier M, de Groot R, Usuf E, Voice M, Calvo-Bado L, Mallet F, Fidler K, Levin M, Carrol ED, Emonts M, von Both U, PERFORM Consortium 20/03/2024
Rapid emergence of transmissible SARS-CoV-2 variants in mild community cases. Microbiology Spectrum Letter Crone MA, Hakki S, Fenn J, Zhou J, Oliveira CRD, Madon KJ, Koycheva A, Badhan A, Jonnerby J, Nevin S, Conibear E, Derelle R, Varro R, Luca C, Ahmad S, Zambon M, Barclay WS, Dunning J, Freemont PS, Taylor GP, Lalvani A 14/03/2024
Rapid expansion and international spread of M1UK in the post-pandemic UK upsurge of Streptococcus pyogenes Nature Communications Journal Article Ana Vieira1,2,3, Yu Wan1,3,4, Yan Ryan5, Ho Kwong Li1,2, Rebecca L Guy4,  Maria Papangeli1,2, Kristin K Huse1,2, Lucy C Reeves1,2, Valerie WC Soo1,2, Roger Daniel5, Alessandra Harley5, Karen Broughton5, Chenchal Dhami5, Mark Ganner5, Marjorie Ganner5, Zaynab Mumin5, Maryam Razaei5, Emma Rundberg5, Rufat Mammadov5, Ewurabena A Mills1,2, Vincenzo Sgro1, Kai Yi Mok1, Xavier Didelot6, Nicholas J Croucher7,8, Elita Jauneikaite3,7,8, Theresa Lamagni3,4, Colin S Brown3,4, Juliana Coelho†3,4,5, Shiranee Sriskandan†1,2,3, Sriskandan S 10/05/2024
Specificity of the Modified Jones Criteria. Pediatrics Journal Article Pulle J, Ndagire E, Atala J, Fall N, Okello E, Oyella LM, Rwebembera J, Sable C, Parks T, Sarnacki R, Nakitto M, de Loizaga SR, Wirth S, Carapetis J, Beaton A 01/03/2024
Structural and functional diversity of type IV secretion systems Nature Reviews Microbiology Review, Early Access, Journal Costa TRD, Patkowski JB, Mace K, Christie PJ, Waksman G 09/10/2023
The antiviral potential of the antiandrogen enzalutamide and the viral-androgen signaling interplay in seasonal coronaviruses. Journal of Medical Virology Journal Article Ogunjinmi OD, Abdullahi T, Somji R-A, Bevan CL, Barclay WS, Temperton N, Brooke GN, Giotis ES 01/03/2024
The HIV Empowering Adults’ Decisions to Share: UK/Uganda (HEADS-UP) Study-A Randomised Feasibility Trial of an HIV Disclosure Intervention for Young Adults with Perinatally Acquired HIV. AIDS and Behavior Journal Article Evangeli M, Gnan G, Musiime V, Fidler S, Seeley J, Frize G, Uwizera A, Lisi M, Foster C 15/03/2024
The prevalence of cardiovascular disease risk factors among adults living in extreme poverty. Nature Human Behaviour Journal Article Geldsetzer P, Tisdale RL, Stehr L, Michalik F, Lemp J, Aryal KK, Damasceno A, Houehanou C, Jørgensen JMA, Lunet N, Mayige M, Saeedi Moghaddam S, Mwangi KJ, Bommer C, Marcus M-E, Theilmann M, Ebert C, Atun R, Davies JI, Flood D, Manne-Goehler J, Seiglie J, Bärnighausen T, Vollmer S 13/03/2024
Virology, pathogenesis, epidemiology and clinical management of HTLV-1 infection. Proceedings of the 30th HTLV European research network (HERN 2023) Journal of Osteopathic Medicine Article de Mendoza C, Taylor G, Gessain A, Thoma-Kress AK, Bangham C, Vesterbacka J, Accolla R, Bazarbachi A, van Weyenbergh J, Cook L, Casseb J, Ramos JC, Rosadas C, Macchi B, Cassar O, Soriano V 01/03/2024
Water, health, and peace: a call for interdisciplinary research. The Lancet Journal Article Abbara A, Abu Shomar R, Daoudy M, Abu Sittah G, Zaman MH, Zeitoun M 21/03/2024
Which low urgent triaged febrile children are suitable for a fast track? An observational European study. Emergency Medicine Journal Observational Study, Journal Article Tan CD, Vermont CL, Zachariasse JM, von Both U, Carrol ED, Eleftheriou I, Emonts M, van der Flier M, Herberg J, Kohlmaier B, Levin M, Lim E, Maconochie IK, Martinon-Torres F, Nijman RG, Pokorn M, Rivero-Calle I, Rudzāte A, Tsolia M, Zenz W, Zavadska D, Moll HA, PERFORM consortium (Personalised Risk assessment in febrile children to optimise Real-life Management across the European Union) 21/03/2024
Zombie malaria parasites Science Commentary article Carlton J, Cunnington A 03/05/2024