Congratulations to members of the Department who have recently had their research findings published. Here’s our round-up of the latest publication successes.
To ensure the quality and accuracy of the information published on this blog, we source our data directly from Symplectic. Our reports are generated on a monthly basis, which means there may be a delay in publicising some publications.
| Title | Canonical journal title | Publication type | Authors OR Authors/Contributors | Publication date |
| A computational framework to improve cross-platform implementation of transcriptomics signatures. | EBioMedicine | Journal Article, Review | Kreitmann L, D’Souza G, Miglietta L, Vito O, Jackson HR, Habgood-Coote D, Levin M, Holmes A, Kaforou M, Rodriguez-Manzano J | 19/06/2024 |
| A Nanopore Sequencing-based Pharmacogenomic Panel to Personalize Tuberculosis Drug Dosing. | American Journal of Respiratory and Critical Care Medicine | Journal Article | Verma R, da Silva KE, Rockwood N, Wasmann RE, Yende N, Song T, Kim E, Denti P, Wilkinson RJ, Andrews JR | 15/06/2024 |
| A targeted single mutation in influenza A virus universal epitope transforms immunogenicity and protective immunity via CD4<SUP>+</SUP> T cell activation | Cell Reports | Article, Journal | Hulin-Curtis S, Geary JK, Maclachlan BJ, Altmann DM, Baillon L, Cole DK, Greenshields-Watson A, Hesketh SJ, Humphreys IR, Jones IM, Lauder SN, Mason GH, Smart K, Scourfield DO, Scott J, Sukhova K, Stanton RJ, Wall A, Rizkallah PJ, Barclay WS, Gallimore A, Godkin A | 25/06/2024 |
| Age-specific nasal epithelial responses to SARS-CoV-2 infection (Vol 6, pg 1293, 2024) | Nature Microbiology | Correction, Early Access, Journal | Woodall MNJ, Cujba A-M, Worlock KB, Case K-M, Masonou T, Yoshida M, Polanski K, Huang N, Lindeboom RGH, Mamanova L, Bolt L, Richardson L, Cakir B, Ellis S, Palor M, Burgoyne T, Pinto A, Moulding D, Mchugh TD, Saleh A, Kilich E, Mehta P, O’Callaghan C, Zhou J, Barclay W, De Coppi P, Butler CR, Cortina-Borja M, Vinette H, Roy S, Breuer J, Chambers RC, Heywood WE, Mills K, Hynds RE, Teichmann SA, Meyer KB, Nikolic MZ, Smith CM | 01/05/2024 |
| Associations between HIV stigma and health-related quality-of-life among people living with HIV: cross-sectional analysis of data from HPTN 071 (PopART). | Scientific Reports | Journal Article | Hall E, Davis K, Ohrnberger J, Pickles M, Gregson S, Thomas R, Hargreaves JR, Pliakas T, Bwalya J, Dunbar R, Mainga T, Shanaube K, Hoddinott G, Bond V, Bock P, Ayles H, Stangl AL, Donnell D, Hayes R, Fidler S, Hauck K, HPTN 071 (PopART) study team | 04/06/2024 |
| Bacterial esterases reverse lipopolysaccharide ubiquitylation to block host immunity. | Cell Host and Microbe | Journal Article | Szczesna M, Huang Y, Lacoursiere RE, Bonini F, Pol V, Koc F, Ward B, Geurink PP, Pruneda JN, Thurston TLM | 12/06/2024 |
| Cell Culture Evaluation Hints Widely Available HIV Drugs Are Primed for Success if Repurposed for HTLV-1 Prevention. | Pharmaceuticals | Journal Article | Kalemera MD, Maher AK, Dominguez-Villar M, Maertens GN | 05/06/2024 |
| Ciprofloxacin prophylaxis during haematopoietic cell transplantation: a role for use in patients with germ cell tumours? | Journal of Medical Microbiology | Journal Article | Kavallieros K, Baltas I, Konstantinou G, Koutoumanou E, Gibani MM, Gilchrist M, Davies F, Pavlu J | 01/06/2024 |
| Classification of early tuberculosis states to guide research for improved care and prevention: an international Delphi consensus exercise | The Lancet Respiratory Medicine | Article, Journal | Coussens AK, Zaidi SMA, Allwood BW, Dewan PK, Gray G, Kohli M, Kredo T, Marais BJ, Marks GB, Martinez L, Ruhwald M, Scriba TJ, Seddon JA, Tisile P, Warner DF, Wilkinson RJ, Esmail H, Houben RMGJ | 01/06/2024 |
| Development of an inhibitor of the mutagenic SOS response that suppresses the evolution of quinolone antibiotic resistance | Chemical Science | Article, Early Access, Journal | Bradbury JD, Hodgkinson T, Thomas AM, Tanwar O, La Monica G, Rogga VV, Mackay LJ, Taylor EK, Gilbert K, Zhu Y, Sefton AY, Edwards AM, Gray-Hammerton CJ, Smith GR, Roberts PM, Walsh TR, Lanyon-Hogg T | 16/06/2024 |
| Drug-Resistant Tuberculosis Case-Finding Strategies: Scoping Review. | JMIR Public Health and Surveillance | Journal Article, Review | van Wyk SS, Nliwasa M, Lu F-W, Lan C-C, Seddon JA, Hoddinott G, Viljoen L, Günther G, Ruswa N, Shah NS, Claassens M | 26/06/2024 |
| Epidemiology and Management of Pediatric Group A Streptococcal Pneumonia With Parapneumonic Effusion: An Observational Study. | The Pediatric Infectious Disease Journal | Journal Article | Lees EA, Williams TC, Marlow R, Fitzgerald F, Jones C, Lyall H, Bamford A, Pollock L, Smith A, Lamagni T, Kent A, Whittaker E, Group A Streptococcal Disease Consortium | 19/06/2024 |
| Evaluating the dynamics of hospital COVID-19 contacts and subsequent conversion to SARS-CoV-2 infection: a multi-centre retrospective cohort study | Infection Prevention in Practice | Article, Journal | Okeke N, Snell LB, Rathish B, Hussein A, Newsholme W, Mack D, Breathnach A, Otter JA | 01/06/2024 |
| Exploring real-world vancomycin target attainment in neonatal intensive care in the context of Staphylococcal infections: a retrospective observational cohort study. | Journal of Infection | Journal article | Blank M, Wilson RC, Wan Y, Peters J, Davies F, Tyszczuk L, Pichon B, Riezk A, Demirjian A, Brown CS, Gilchrist M, Holmes AH, Rawson TM | 05/06/2024 |
| Global trends in carbapenem- and difficult-to-treat-resistance among World Health Organization priority bacterial pathogens: ATLAS surveillance program 2018-2022 | Journal of Global Antimicrobial Resistance | Article, Journal | Wise MG, Karlowsky JA, Mohamed N, Hermsen ED, Kamat S, Townsend A, Brink A, Soriano A, Paterson DL, Moore LSP, Sahm DF | 01/06/2024 |
| Gut microbes coordinate pulmonary immunity. | Proceedings of the National Academy of Sciences of USA | Journal Article, Comment | Christodoulou C, Clarke TB | 18/06/2024 |
| Highlights from the 31st CROI: key communications with potential impact on future HIV clinical practice | Review | Alagaratnam J, Levi LI, van Bremen K, Mastrangelo A, Ambrosioni J | 06/06/2024 | |
| Household contact management and preventive treatment for drug-resistant tuberculosis | The Lancet Global Health | Journal article | Seddon J, McQuaid C, Mafirakureva N, Hesseling A, Fox G, Dodd P | 24/06/2024 |
| Human antibody signatures towards the <i>Chlamydia trachomatis</i> major outer membrane protein after natural infection and vaccination | EBioMedicine | Article, Journal | Rosenkrands I, Olsen AW, Knudsen S, Dehari N, Juel HB, Cheeseman HM, Andersen P, Shattock RJ, Follmann F | 01/06/2024 |
| Human SARS-CoV-2 challenge uncovers local and systemic response dynamics. | Nature | Journal Article | Lindeboom RGH, Worlock KB, Dratva LM, Yoshida M, Scobie D, Wagstaffe HR, Richardson L, Wilbrey-Clark A, Barnes JL, Kretschmer L, Polanski K, Allen-Hyttinen J, Mehta P, Sumanaweera D, Boccacino JM, Sungnak W, Elmentaite R, Huang N, Mamanova L, Kapuge R, Bolt L, Prigmore E, Killingley B, Kalinova M, Mayer M, Boyers A, Mann A, Swadling L, Woodall MNJ, Ellis S, Smith CM, Teixeira VH, Janes SM, Chambers RC, Haniffa M, Catchpole A, Heyderman R, Noursadeghi M, Chain B, Mayer A, Meyer KB, Chiu C, Nikolić MZ, Teichmann SA | 19/06/2024 |
| Impact of interrupting antiretroviral therapy started during primary HIV-1 infection on plasma neurofilament light chain protein, a marker of neuronal injury: the SPARTAC trial | Journal of Virus Eradication | Journal article | Alagaratnam J, Stöhr W, Hamlyn E, Porter K, Toombs J, Heslegrave A, Zetterberg H, Gisslén M, Underwood J, Schechter M, Kaleebu P, Tambussi G, Kinloch S, Miro JM, Kelleher AD, Babiker A, Frater J, Winston A, Fidler S | 01/06/2024 |
| Individuals with JAK1 variants are affected by syndromic features encompassing autoimmunity, atopy, colitis, and dermatitis. | Journal of Experimental Medicine | Systematic Review, Journal Article | Horesh ME, Martin-Fernandez M, Gruber C, Buta S, Le Voyer T, Puzenat E, Lesmana H, Wu Y, Richardson A, Stein D, Hodeib S, Youssef M, Kurowski JA, Feuille E, Pedroza LA, Fuleihan RL, Haseley A, Hovnanian A, Quartier P, Rosain J, Davis G, Mullan D, Stewart O, Patel R, Lee AE, Rubinstein R, Ewald L, Maheshwari N, Rahming V, Chinn IK, Lupski JR, Orange JS, Sancho-Shimizu V, Casanova J-L, Abul-Husn NS, Itan Y, Milner JD, Bustamante J, Bogunovic D | 03/06/2024 |
| Is d -dimer a Useful Diagnostic Tool for Identifying Multisystem Inflammatory Syndrome in Children in Critically Unwell Children? | The Pediatric Infectious Disease Journal | Journal Article | Duret A, Patel H, Lakkineni L, Roy RB, Mitting R, Whittaker E | 05/06/2024 |
| Is detergent-only cleaning paired with chlorine disinfection the best approach for cleaning? | Journal of Hospital Infection | Editorial Material, Journal | Kiernan MA, Garvey MI, Norville P, Otter JA, Weber DJ | 01/06/2024 |
| Levelling the playing field through the London Network of the UK clinical trials accelerator platform | Contemporary Clinical Trials Communications | Article, Journal | Matthews J, Dobra R, Wilson G, Allen L, Bossley C, Brendell R, Brugha R, Brown D, Brown S, Cadiente S, Cameron L, Davies G, Dawson C, Elborn S, Hughes D, Longmate J, Macedo P, Pappas L, Pao C, Round C, Ruiz G, Saunders C, Shafi N, Simmonds N, Waller M, Watson D, Davies JC | 01/06/2024 |
| Modulation of Salmonella virulence by a novel SPI-2 injectisome effector that interacts with the dystrophin-associated protein complex. | mBio | Journal Article | Yu X-J, Xie H, Li Y, Liu M, Hou R, Predeus AV, Perez Sepulveda BM, Hinton JCD, Holden DW, Thurston TLM | 21/06/2024 |
| Overview of the Participation of Nurses in Antimicrobial Stewardship Activities. | Clinical Therapeutics: the international peer-reviewed journal of drug therapy | Journal Article | Castro-Sánchez E | 01/06/2024 |
| Phage-host co-evolution has led to distinct generalized transduction strategies | Nucleic Acids Research | Article, Early Access, Journal | Wolput S, Lood C, Fillol-Salom A, Casters Y, Albasiony A, Cenens W, Vanoirbeek K, Kerremans A, Lavigne R, Penades JR, Aertsen A | 22/07/2024 |
| Population incidence and associated mortality of urinary tract infection in people living with dementia | Journal of Infection | Article, Journal | Lai H, Kolanko M, Li LM, Parkinson ME, Bourke NJ, Graham NSN, David MCB, Mallas E-J, Su B, Daniels S, Wilson D, Golemme M, Norman C, Jensen K, Jackson R, Tran M, Freemont PS, Wingfield D, Wilkinson T, Gregg EW, Tzoulaki I, Sharp DJ, Soreq E | 01/06/2024 |
| Protocol for a semi-quantitative approach to identify protein S-palmitoylation in cultured cells by acyl biotin exchange assay | STAR Protocols | Article | Leishman S, Aljadeed NMN, Anand P | 21/06/2024 |
| Providing urgent and emergency care to children and young people: training requirements for emergency medicine specialty trainees. | European Journal of Emergency Medicine | Journal Article | Nijman RG, Schickerling C, Bognar Z, Brown R | 03/06/2024 |
| Respiratory health and the Syrian conflict: a scoping literature review. | Medicine, Conflict and Survival | Journal Article, Review | Basha L, Hamze M, Socarras A, Akhtar M, Albaik A, Hussien I, Tarakji A, Hamadeh M, Loutfi R, Kewara M, Abbara A | 01/06/2024 |
| Sex inequalities in cardiovascular risk prediction. | Cardiovascular Research | Journal Article | Elliott J, Bodinier B, Whitaker M, Wada R, Cooke G, Ward H, Tzoulaki I, Elliott P, Chadeau-Hyam M | 04/06/2024 |
| Should we worry about a growing threat from ” bird flu “? A major human outbreak of H5N1 is plausible, and the risk is high | BMJ: British Medical Journal | Editorial Material, Journal | Dye C, Barclay WS | 04/06/2024 |
| Structural basis of broad SARS-CoV-2 cross-neutralization by affinity-matured public antibodies. | Cell Reports Medicine | Journal Article | Sheward DJ, Pushparaj P, Das H, Greaney AJ, Kim C, Kim S, Hanke L, Hyllner E, Dyrdak R, Lee J, Dopico XC, Dosenovic P, Peacock TP, McInerney GM, Albert J, Corcoran M, Bloom JD, Murrell B, Karlsson Hedestam GB, Hällberg BM | 18/06/2024 |
| Sustained transmission over two decades of a previously unrecognised MPT64 negative Mycobacterium tuberculosis strain in Queensland, Australia: a whole genome sequencing study | The Lancet Regional Health. Western Pacific | Journal article | Bainomugisa A, Pandey S, O’Connor B, Syrmis M, Whiley D, Sintchenko V, Coin LJM, Marais BJ, Coulter C | 01/06/2024 |
| Systemic prime mucosal boost significantly increases protective efficacy of bivalent RSV influenza viral vectored vaccine. | npj Vaccines | Journal Article | Bissett C, Belij-Rammerstorfer S, Ulaszewska M, Smith H, Kailath R, Morris S, Powers C, Sebastian S, Sharpe HR, Allen ER, Wang Z, Cunliffe RF, Sallah HJ, Spencer AJ, Gilbert S, Tregoning JS, Lambe T | 26/06/2024 |
| The HIV Empowering Adults’ Decisions to Share: UK/Uganda (HEADS-UP) Study-A Randomised Feasibility Trial of an HIV Disclosure Intervention for Young Adults with Perinatally Acquired HIV | AIDS and Behavior | Article, Early Access, Journal | Evangeli M, Gnan G, Musiime V, Fidler S, Seeley J, Frize G, Uwizera A, Lisi M, Foster C | 01/06/2024 |
| Towards a machine-learning assisted non-invasive classification of dengue severity using wearable PPG data: a prospective clinical study. | EBioMedicine | Journal Article, Observational Study | Karolcik S, Manginas V, Chanh HQ, Daniels J, Giang NT, Huyen VNT, Hoang MTV, Phan Nguyen Quoc K, Hernandez B, Ming DK, Nguyen Van H, Phan TQ, Trieu HT, Luong Thi Hue T, Holmes AH, Thwaites L, Phan Vinh T, Yacoub S, Georgiou P, Vietnam ICU Translational Applications Laboratory (VITAL) Investigators | 01/06/2024 |
| Uncovering strain- and age-dependent innate immune responses to SARS-CoV-2 infection in air-liquid-interface cultured nasal epithelia | iScience | Article, Journal | Chang JJ-Y, Grimley SL, Tran BM, Deliyannis G, Tumpach C, Nguyen ANT, Steinig E, Zhang J, Schroder J, Caly L, McAuley J, Wong SL, Waters SA, Stinear TP, Pitt ME, Purcell D, Vincan E, Coin LJM | 21/06/2024 |
| Varicella zoster virus-induced autophagy in human neuronal and hematopoietic cells exerts antiviral activity. | Journal of Medical Virology | Journal Article | Heinz JL, Hinke DM, Maimaitili M, Wang J, Sabli IKD, Thomsen M, Farahani E, Ren F, Hu L, Zillinger T, Grahn A, von Hofsten J, Verjans GMGM, Paludan SR, Viejo-Borbolla A, Sancho-Shimizu V, Mogensen TH | 01/06/2024 |