Latest publications: November 2024

Congratulations to members of the Department who have recently had their research findings published. Here’s our round-up of the latest publication successes.


To ensure the quality and accuracy of the information published on this blog, we source our data directly from Symplectic. Our reports are generated on a monthly basis, which means there may be a delay in publicising some publications.

 

Title Canonical journal title Publication type Authors OR Authors/Contributors Publication date
‘That’s funny’: creative solutions for time-starved researchers Nature Journal article Tregoning J, Tillotson R 28/11/2024
A ‘sort and sequence’ approach to dissect heterogeneity of response to a self-amplifying RNA (saRNA) vector in a novel human muscle cell line Molecular Therapy: Nucleic Acids Journal article Barton RD, Tregoning JS, Wang Z, Gonçalves-Carneiro D, Patel R, McKay PF, Shattock RJ 26/11/2024
A matrix tool to foster patient engagement in children, adolescents and young adults: report from a multistakeholder workshop Research Involvement and Engagement Journal article Cavaller-Bellaubi M, Degraeuwe E, Vande Walle J, Gasthuys E, Prytula A, Allegaert K, Bertolani A, Bonifazi D, Boven K, Breitenstein S, Clark A, Claverol J, Corriol-Rohou S, Crawley F, de Bruyne R, de Groote K, de Guchtenaere A, de Lisa R, Dehlinger-Kremer M, Egger G, Eygenraam M, Ferrer E, Furlong P, Davies EH, Jonker A, Lepola P, Lopez E, Mahler F, Mavris M, Nafria B, Natale A, Nuytinck L, Ollivier C, Preston J, Raes A, Scheeren J, Schmidt J, Schmidt-Goldstein S, Snauwaert E, Tan L, Tenningkeit F, Turner M, Van Meel M, Wyngaert KV, Vlaeminck A, Vroom E, West L 27/11/2024
A meta-analysis of levofloxacin for contacts of multidrug-resistant TB Journal article Duong T, Brigden J, Schaaf HS, Garden F, Marais B, Thu Anh N, White I, Gibb D, Viet Nhung N, Martinson N, Fairlie L, Martinez L, Layton C, Benedetti A, Marks G, Turner R, Seddon J, Hesseling AC, Fox GJ 18/12/2024
A multicentre observational study of paediatric head and neck abscesses International Journal of Pediatric Otorhinolaryngology Journal article Davies T, Markey A, Janjua N, Chan J, Stephenson K, Newport H, Kunanandam T, English C, Nichani J, Harbert K, Bhargava E, Pankhania M, Tabaksert A, Powell S, Davis E, Brown R, Costello R, Sandeman J, O’Donnell S, Consunji M, Brown R, Coyle P, Ward J, Whittaker E, Fearing A, Elmarghani M, Montague M-L, Krishnan M 01/11/2024
A prophage competition element protects Salmonella from lysis Cell Host and Microbe Journal article Sargen MR, Helaine S 06/11/2024
Accessing breast cancer care in a protracted conflict: Qualitative exploration of the perspectives of women with breast cancer in northwest Syria Social Science and Medicine Journal article Marzouk M, Hamze M, Debel J, Alshemali A, Alameen BA, Bakkour M, Galal B, Chagpar AB, Atassi B, Khoshnood K, Abbara A 01/11/2024
Advances in diagnosis and prognosis of bacteraemia, bloodstream infection, and sepsis using machine learning: A comprehensive living literature review Artificial Intelligence in Medicine Journal article Henandez B., Ming D.K., Rawson T.M, Bolton W., Wilson R., Vasikasin V., , J. R-M, F.J. D, P. G, A.H. H 01/11/2024
Age-specific nasal epithelial responses to SARS-CoV-2 infection (Vol 6, pg 1293, 2024) Nature Microbiology Journal article Woodall MNJ, Cujba A-M, Worlock KB, Case K-M, Masonou T, Yoshida M, Polanski K, Huang N, Lindeboom RGH, Mamanova L, Bolt L, Richardson L, Cakir B, Ellis S, Palor M, Burgoyne T, Pinto A, Moulding D, Mchugh TD, Saleh A, Kilich E, Mehta P, O’Callaghan C, Zhou J, Barclay W, De Coppi P, Butler CR, Cortina-Borja M, Vinette H, Roy S, Breuer J, Chambers RC, Heywood WE, Mills K, Hynds RE, Teichmann SA, Meyer KB, Nikolic MZ, Smith CM 01/11/2024
Anakinra for dengue patients with hyperinflammation: protocol for a randomized double-blind placebo-controlled trial Wellcome Open Research Journal article Huyen TB, Trieu HT, Vuong NL, Minh Nguyet N, Tam DTH, McBride A, Linh NTM, Thuan DT, Phong NT, Trung TN, Huong NTC, Vien TTD, Duyen HTL, Hoa VTM, Watson J, Geskus R, Tho PV, Kestelyn E, Qui PT, Yacoub S 22/11/2024
Antibiotic-recalcitrant Salmonella during infection Nature Reviews Microbiology Journal article Giorgio RT, Helaine S 18/11/2024
Antiviral effect of Evusheld in COVID-19 hospitalized patients infected with pre-Omicron or Omicron variants: a modelling analysis of the randomized DisCoVeRy trial Journal of Antimicrobial Chemotherapy Journal article Beaulieu M, Gaymard A, Massonnaud C, Peiffer-Smadja N, Bouscambert-Duchamp M, Carcelain G, Lingas G, Mentré F, Ader F, Hites M, Poignard P, Guedj J 04/11/2024
Approaches and processes for paediatric chest X-ray classification used in the SHINE TB treatment-shortening trial International Journal of Tuberculosis and Lung Disease Journal article Palmer M, van der Zalm MM, Schaaf HS, Goussard P, Morrison J, Seddon JA, Hissar S, Baskaran D, Kinikar A, Raichur P, Wobudeya E, Chabala C, Lebeau K, Crook AM, Turkova A, Gibb D, Hesseling AC 01/11/2024
ARF6 as a Novel Activator of HIF-2α in Pulmonary Arterial Hypertension American Journal of Respiratory Cell and Molecular Biology Journal article Wojciak-Stothard B 13/11/2024
Association of prior tuberculosis with cardiovascular status in perinatally HIV-1-infected adolescents Open Heart Journal article Magodoro IM, Guerrero-Chalela CE, Carkeek E, Asafu-Agyei NA, Jele N, Frigati LJ, Myer L, Jao J, Ntsekhe M, Wilkinson KA, Wilkinson RJ, Zar H, Ntusi N 14/11/2024
Brazil takes a leap towards the elimination of HTLV-1 vertical transmission The Lancet Regional Health. Americas Journal article Rosadas C, Barreira D, Gaspar PC, Aragón MG, Oliveira A, Assone T, Miranda AE 01/11/2024
Diagnostic accuracy of TB screening tests in a prospective multinational cohort: chest-X-ray with computer-aided detection, Xpert TB host response, and C-reactive protein Clinical Infectious Diseases Journal article Crowder R, Thangakunam B, Andama A, Christopher DJ, Dalay V, Nwamba W, Kik SV, Van Nguyen D, Nhung NV, Phillips PPJ, Ruhwald M, Theron G, Worodria W, Yu C, Nahid P, Cattamanchi A, Gupta-Wright A, Denkinger CM 07/11/2024
Diagnostics for optimised dengue surveillance: a qualitative focus group study to investigate user experience and requirements in Thailand BMJ Open Journal article Arkell P, Ketklao S, Songjaeng A, Mairiang D, Rodriguez-Manzano J, Georgiou P, Holmes A, Ahmad R, Malasit P, Avirutnan P, Lawpoolsri S 20/11/2024
Distinct neutrophil effector functions in response to different isolates of Leishmania aethiopica Parasites and Vectors Journal article Adem E, Cruz Cervera E, Yizengaw E, Takele Y, Shorter S, Cotton JA, Getti G, Kropf P 11/11/2024
Escherichia coli from six European countries reveals differences in profile and distribution of critical antimicrobial resistance determinants within One Health compartments, 2013 to 2020 Eurosurveillance Journal article Kaspersen HP, Brouwer MSM, Nunez-Garcia J, Cárdenas-Rey I, AbuOun M, Duggett N, Ellaby N, Delgado-Blas J, Hammerl JA, Getino M, Serna C, Naas T, Veldman KT, Bossers A, Sunde M, Mo SS, Jørgensen SB, Ellington M, Gonzalez-Zorn B, La Ragione R, Glaser P, Anjum MF 21/11/2024
Expert consensus on antimicrobial resistance research priorities to focus development and implementation of antibacterial vaccines and monoclonal antibodies Eurosurveillance Journal article Hassoun-Kheir N, Guedes M, Arieti F, Pezzani MD, Gladstone BP, Robotham JV, Pouwels KB, Kingston R, Carmeli Y, Cassini A, Cecchini M, Drobniewski F, Frost I, Geurtsen J, Kronenberg A, Htay MNN, Paul M, Rocha-Pereira N, Rodríguez-Baño J, Scudeller L, Stewardson AJ, Tacconelli E, Harbarth S, Vella V, de Kraker MEA 21/11/2024
Exploring relationships between conflict intensity, forced displacement, and healthcare attacks: a retrospective analysis from Syria, 2016–2022 Conflict and Health Journal article Tarnas MC, Hamze M, Tajaldin B, Sullivan R, Parker DM, Abbara A 21/11/2024
Footprints of innate immune activity during HIV-1 reservoir cell evolution in early-treated infection Journal of Experimental Medicine Journal article Sun W, Gao C, Gladkov GT, Roseto I, Carrere L, Parsons EM, Gasca-Capote C, Frater J, Fidler S, Yu XG, Lichterfeld M, Sandström E, Darbyshire J, Post F, Conlon C, Anderson J, Maini M, Peto T, Sasieni P, Miller V, Weller I, Fidler S, Frater J, Babiker A, Stöhr W, Pett S, Dorrell L, Pace M, Olejniczak N, Brown H, Robinson N, Kopycinski J, Yang H, Hanke T, Crook A, Kaye S, McClure M, Erlwein O, Lovell A, Khan M, Gabriel M, Bennett R, Sy A, Gregory A, Hudson F, Russell C, Wood G, Box H, Kingsley C, Topping K, Lever A, Wills M, Fun A, Bandara M, Kelly D, Collins S, Markham A, Rauchenberger M, Sowunmi Y, Shidfar S, Hague D, Fidler S, Pett S, Nelson M, Cerrone M, Castrillo Martinez N, Barber T, Schoolmeesters A, Weaver C, Thunder O, Rowlands J, Higgs C, Fedele S, Bracchi M, Thomas L, Bourke P, Nwokolo N, Lawrenson G, Fiorino M, Lukha H, Kinloch S, Johnson M, Nightingale A, Ngwu N, Byrne P, Cuthbertson Z, Jones M, Fernandez T, Clarke A, Fisher M, Gleig R, Trevitt V, Fitzpatrick C, Adams T, Finnerty F, Thornhill J, Lewis H, Kuldanek K, Fox J, Lwanga J, Uzu H, Lee M, Merle S, O’Rourke P, Jendrulek I, ZarkoFlynn T, Taylor M, Tiraboschi JM, Murray T 04/11/2024
Fungal lung disease European Respiratory Journal Journal article Jaggi TK, Agarwal R, Tiew PY, Shah A, Lydon EC, Hage CA, Waterer GW, Langelier CR, Delhaes L, Chotirmall SH 01/11/2024
Germline Natural killer cell receptors modulating the T cell response Frontiers in Immunology Journal article Mora-Bitria L, Asquith B 04/11/2024
Imaging in early tuberculosis Thorax Journal article Wilkinson R 14/11/2024
Impact of antiretroviral therapy during primary HIV infection on T‐cell immunity after treatment interruption European Journal of Immunology Journal article Tipoe T, Ogbe A, Lee M, Brown H, Robinson N, Hall R, Petersen C, Lewis H, Thornhill J, Ryan F, Fox J, Fidler S, Frater J 01/11/2024
Inno4Vac Workshop Report Part 1: Controlled Human Influenza Virus Infection Model (CHIVIM) Strain Selection and Immune Assays for CHIVIM Studies, November 2021, MHRA, UK Influenza and Other Respiratory Viruses Journal article Waldock J, Cox RJ, Chiu C, Subbarao K, Wildfire A, Barclay W, van Kasteren PB, McCauley J, Russell CA, Smith D, Thwaites RS, Tregoning JS, Engelhardt OG 01/11/2024
Interventional anti-reflux management for gastro-oesophageal reflux disease in lung transplant recipients: a systematic review and meta-analysis Surgical Endoscopy: surgical and interventional techniques Journal article Krahelski O, Ali I, Namgoong C, Dave K, Reed A, Ashrafian H, Reddy M, Khan O, Das B, Fehervari M 25/11/2024
Mechanism for Vipp1 spiral formation, ring biogenesis, and membrane repair Nature Structural and Molecular Biology Journal article Naskar S, Merino A, Espadas J, Singh J, Roux A, Colom A, Low HH 11/11/2024
Modulating cytokine microenvironment during T cell activation induces protective RSV-specific lung resident memory T cells in early life in mice Journal article Wang Z, Miko Z, Thomas C, Kinnear E, Holder B, Rice T, Kampmann B, Tregoning J 31/12/2024
Molecular basis of FIGNL1 in dissociating RAD51 from DNA and chromatin Science Journal article Carver A, Yu T-Y, Yates LA, White T, Wang R, Lister K, Jasin M, Zhang X 05/12/2024
Monkeypox virus isolation from longitudinal samples in 11 hospitalised patients Lancet Infectious Diseases Journal article Callaby H, Olver J, Emery K, Richards KS, Killip M, Groves N, Beadsworth MBJ, Price DA, Cooke GS, Collini P, Cole J, Dunning J, Semple MG, Baillie JK, Carson G, Openshaw P, Merson L, Russell CD, Zambon M, Chand M, Tedder R, Khoo S, Horby P, Turtle LCW, Solomon T, Ijaz S, Fletcher T, Palmarini M, Ho A, Price N, Alex B, Andrikopoulos P, Black B, Barclay WS, Bogaert D, Chechi K, Da Silva Filipe A, De Silva T, Docherty AB, Dos Santos Correia G, Dumas M-E, Green CA, Greenhalf W, Griffin JL, Gupta R, Harrison EM, Holden K, Klenerman P, Law A, Lewis MR, Liggi S, Lim WS, Maslen L, Mentzer AJ, Meynert A, Moore S, Noursadeghi M, Olanipekun M, Osagie A, Palmieri C, Paxton WA, Pollakis G, Rambaut A, Robertson D, Sancho-Shimizu V, Sands CJ, Scott JT, Sigfrid L, Sriskandan S, Stuart D, Summers C, Swann OV, Takats Z, Takis P, Thompson AAR, Thomson EC, Thwaites RS, Hardwick H, Oosthuyzen W, Ostermann M, Rampling T, Houlihan CF 28/11/2024
Multi‐site Ultrasound‐guided Fine Needle Aspiration to Study Cells and Soluble Factors From Human Lymph Nodes Current Protocols in Neuroscience Journal article Al‐Diwani A, Agrawal D, Sheerin F, Board C, Irani SR, Pollock KM, Provine NM 01/11/2024
Non-invasive in vivo sensing of bacterial implant infection using catalytically-optimised gold nanocluster-loaded liposomes for urinary readout Nature Communications Journal article Chen K, Najer A, Charchar P, Saunders C, Thanapongpibul C, Kloeckner A, Chami M, Peeler D, Silva I, Panariello L, Karu K, Loynachan C, Frenette L, Potter M, Tregoning J, Parkin IP, Edwards AM, Clarke TB, Yarovsky M, Stevens M 28/11/2024
Our evolving understanding of the impact of primary HIV infection on brain health Brain: a journal of neurology Journal article Winston A, Henderson M 04/11/2024
Predicting deterioration in dengue using a low cost wearable for continuous clinical monitoring npj Digital Medicine Journal article Ming D, Daniels J, chanh HQ, Karolcik S, Hernandez-Perez B, Manginas V, Nguyen VH, Nguyen QH, Phan TQ, Luong THT, Trieu HT, Holmes A, Phan VT, Georgiou P, Yacoub S 02/11/2024
Predicting post-COVID-19 condition in children and young people up to 24 months after a positive SARS-CoV-2 PCR-test: the CLoCk study BMC Medicine Journal article Nugawela MD, Stephenson T, Shafran R, Chalder T, Dalrymple E, Ford T, Fox-Smith L, Harnden A, Heyman I, Ladhani SN, McOwat K, Simmons R, Swann O, Whittaker E, De Stavola B, Crawley E, Sharma K, Buszewicz M, Levin M, Garg S, Poustie V, Pinto Pereira SM 07/11/2024
Preventing perinatal HIV acquisition; current gaps and future perspectives Current Opinion in HIV and AIDS Journal article Cockbain B, Fidler S, Lyall H 01/11/2024
Protective immunity to repeated COVID-19 breakthrough infections Clinical Immunology Journal article Altmann DM, Boyton RJ 01/11/2024
SARS-CoV-2 human challenge reveals biomarkers that discriminate early and late phases of respiratory viral infections Nature Communications Journal article Rosenheim J, Gupta RK, Thakker C, Mann T, Bell LCK, Broderick CM, Madon K, Papargyris L, Dayananda P, Kwok AJ, Greenan-Barrett J, Wagstaffe HR, Conibear E, Fenn J, Hakki S, Lindeboom RGH, Dratva LM, Lemetais B, Weight CM, Venturini C, Kaforou M, Levin M, Kalinova M, Mann AJ, Catchpole A, Knight JC, Nikolić MZ, Teichmann SA, Killingley B, Barclay W, Chain BM, Lalvani A, Heyderman RS, Chiu C, Noursadeghi M 30/11/2024
Sputum availability and quality in country-level TB prevalence surveys IJTLD OPEN Journal article Papadopoulou P, Gaeddert M, Gupta-Wright A, Denkinger CM, Marx FM 01/11/2024
Surge of pediatric respiratory tract infections after the COVID-19 pandemic and the concept of “immune debt” Journal of Pediatrics Journal article Lenglart L, Titomanlio L, Bognar Z, Bressan S, Buonsenso D, De T, Farrugia R, Honeyford K, Maconochie IK, Moll HA, Oostenbrink R, Parri N, Roland D, Akyüz Özkan E, Almeida L, Alberti I, Angoulvant F, Assad Z, Aupiais C, Barrett M, Basmaci R, Borensztajn D, Castanhinha S, Chiaretti A, Cohen R, Durnin S, Fitzpatrick P, Greber-Platzer S, Guedj R, Hey F, Jankauskaite L, Keitel K, Mascarenhas I, Milani GP, Musolino AM, Pučuka Z, Ryd Rinder M, Supino MC, Tirelli F, Nijman RG, Ouldali N, Alfven T, Anacleto V, Aydin O, Barber C, Bellelli E, Berant R, De Groc T, Fodor L, Geitoeira S, Gomez B, Hoffmann F, Kohlfuerst D, Kolnik M, Leeb F, Leonard F, Lyttle M, Mação P, Mano L, Morello R, Reis S, Rocha R, Rose K, Rybak A, Salamon P, Saraiva F, Schaffert M, Shahar-Nissan K, Simon G, Costa IS, Marques JS, Starvaggi CA, Teksam O, Thors VS, Thüminger J, Turan C, Velasco R, Vasilico C, Vittucci AC, Zurl C 22/11/2024
The battle against antimicrobial resistance is more important now than ever: time to educate, advocate and act International Journal of Infectious Diseases Journal article Oliveira LMA, Costa NS, Mestrovic T, Jauneikaite E, Pinto TCA 09/11/2024
The drainome: longitudinal metagenomic characterization of wastewater from hospital ward sinks to characterize the microbiome and resistome and to assess the effects of decontamination interventions Journal of Hospital Infection Journal article Snell LB, Prossomariti D, Alcolea-Medina A, Sasson M, Dibbens M, Al-Yaakoubi N, Humayun G, Charalampous T, Alder C, Ward D, Maldonado-Barrueco A, Abadioru O, Batra R, Nebbia G, Otter JA, Edgeworth JD, Goldenberg SD 01/11/2024
The effects of COVID-19 on antifungal prescribing in the UK – lessons to learn Journal of Fungi Journal article Pates K, Shang Z, Jabbar R, Armstrong-James D, Schelenz S, Periselneris J, Arcucci R, Shah A 13/11/2024
The inclusion of children and adolescents in tuberculosis diagnostic development and evaluation–a consensus statement Lancet Infectious Diseases Journal article Bijker EM, Horn L, LaCourse S, MacLean EL, Marais BJ, Nicol MP, Olbrich L, Seddon JA, Sutherland JS, Song R, Zar HJ, Jaganath D 01/11/2024
The lifespan and kinetics of human dendritic cell subsets and their precursors in health and inflammation Journal of Experimental Medicine Journal article Lubin R, Patel AA, Mackerodt J, Zhang Y, Gvili R, Mulder K, Dutertre C-A, Jalali P, Glanville JRW, Hazan I, Sridharan N, Rivkin G, Akarca A, Marafioti T, Gilroy DW, Kandel L, Mildner A, Wilensky A, Asquith B, Ginhoux F, Macallan D, Yona S 04/11/2024
The structural and mechanistic bases for the viral resistance to allosteric HIV-1 integrase inhibitor pirmitegravir mBio Journal article Dinh T, Tber Z, Rey JS, Mengshetti S, Annamalai AS, Haney R, Briganti L, Amblard F, Fuchs JR, Cherepanov P, Kim K, Schinazi RF, Perilla JR, Kim B, Kvaratskhelia M 13/11/2024
Using digital health technologies to optimise antimicrobial use globally The Lancet: Digital Health Journal article Rawson TM, Zhu N, Galiwango R, Cocker D, Islam MS, Myall A, Vasikasin V, Wilson R, Shafiq N, Das S, Holmes AH 01/12/2024
Virion morphology and on-virus spike protein structures of diverse SARS-CoV-2 variants The EMBO Journal Journal article Ke Z, Peacock TP, Brown JC, Sheppard CM, Croll TI, Kotecha A, Goldhill DH, Barclay WS, Briggs JAG 14/11/2024
Virus-modified paraspeckle-like condensates are hubs for viral RNA processing and their formation drives genomic instability Nature Communications Journal article Harper KL, Harrington EM, Hayward C, Anene CA, Wongwiwat W, White RE, Whitehouse A 26/11/2024
What are the unintended patient safety consequences of healthcare technologies? A qualitative study among patients, carers and healthcare providers BMJ Open Journal article Abdelaziz S, Garfield S, Neves AL, Lloyd J, Norton J, van Dael J, Wheeler C, McLeod M, Franklin BD 27/11/2024
Whole Exome Sequencing Identifies Epithelial and Immune Dysfunction‐Related Biomarkers in Food Protein‐Induced Enterocolitis Syndrome Clinical and Experimental Allergy Journal article Camino‐Mera A, Pardo‐Seco J, Bello X, Argiz L, Boyle RJ, Custovic A, Herberg J, Kaforou M, Arasi S, Fiocchi A, Pecora V, Barni S, Mori F, Bracamonte T, Echeverria L, O’Valle‐Aísa V, Hernández‐Martínez NL, Carballeira I, García E, Garcia‐Magan C, Moure‐González JD, Gonzalez‐Delgado P, Garriga‐Baraut T, Infante S, Zambrano‐Ibarra G, Tomás‐Pérez M, Machinena A, Pascal M, Prieto A, Vázquez‐Cortes S, Fernández‐Rivas M, Vila L, Alsina L, Torres MJ, Mangone G, Quirce S, Martinón‐Torres F, Vázquez‐Ortiz M, Gómez‐Carballa A, Salas A 01/11/2024
Wireless implantable bioelectronics with a direct electron transfer lactate enzyme for detection of surgical site infection in orthopaedics Biosensors and Bioelectronics Journal article Gil B, Hall TAG, Freeman DME, Ming D, Kechagias S, Nabilla S, Cegla F, van Arkel RJ 01/11/2024
Inhibitory KIRs decrease HLA class II-mediated protection in Type 1 Diabetes PLOS Genetics Journal article Mora-Bitria L, Debebe BJ, Miners KL, Ladell K, Kaur C, Traherne JA, Jiang W, Price DA, Hadcocks L, McQuibban NAR, Trowsdale J, Wong FS, Pontikos N, Niederalt C, Asquith B  26/12/2024