{"id":574,"date":"2024-07-25T16:00:12","date_gmt":"2024-07-25T15:00:12","guid":{"rendered":"https:\/\/blogs.imperial.ac.uk\/doid-staff\/?p=574"},"modified":"2024-09-25T16:51:48","modified_gmt":"2024-09-25T15:51:48","slug":"digital-diagnostics-for-african-health-systems-in-the-gambia","status":"publish","type":"post","link":"https:\/\/blogs.imperial.ac.uk\/doid-staff\/2024\/07\/25\/digital-diagnostics-for-african-health-systems-in-the-gambia\/","title":{"rendered":"Digital Diagnostics for African Health Systems in The Gambia"},"content":{"rendered":"<figure id=\"attachment_575\" aria-describedby=\"caption-attachment-575\" style=\"width: 1178px\" class=\"wp-caption alignnone\"><img loading=\"lazy\" decoding=\"async\" width=\"2100\" height=\"1158\" class=\"wp-image-575\" src=\"https:\/\/blogs.imperial.ac.uk\/doid-staff\/files\/2024\/07\/Screenshot-2024-07-25-at-15.37.02.png\" alt=\"\" \/><figcaption id=\"caption-attachment-575\" class=\"wp-caption-text\">A group photo of the NIHR Global Health Research Group on Digital Diagnostics for African Health Systems with Gambian stakeholders at the conclusion of the workshop held on June 5, 2024, in Cape Point, The Gambia Credits: Muhammed Jobe, Digital Content Officer, MRCG@LSHTM<\/figcaption><\/figure>\n<h2>From 3-7 June 2024, the <a href=\"https:\/\/www.digitaldiagnostics4africa.org\/nihr-ghrg\">NIHR Global Health Research Group (NIHR GHRG) on Digital Diagnostics for African Health Systems<\/a> convened an in-person workshop at Cape Point, The Gambia. The workshop aimed to gather insights from local stakeholders on the potential and application of portable digital diagnostics within Gambian health systems, and to enhance understanding and facilitate the integration of digital diagnostic tools to improve healthcare delivery in the region. This collaborative event was organised in partnership with the <a href=\"https:\/\/www.lshtm.ac.uk\/research\/units\/mrc-gambia\">MRC Unit The Gambia at London School of Hygiene and Tropical Medicine (MRCG@LSHTM)<\/a>, a key partner in the consortium.<\/h2>\n<p><!--more--><\/p>\n<hr \/>\n<p>During the week, the members of the NIHR GHRG from partner countries and organizations in Africa \u2013 such as University of Ghana, minoHealth AI Lab(Ghana), University of Khartoum (Sudan), University of Nairobi and Masinde Muliro University of Science and Technology (Kenya), Imperial College London, Canterbury Christ Church University, The Institute of Cancer Research, and Malaria Consortium (UK) \u2013 had the opportunity to visit Gambian health centres and meet with collaborators at MRCG@LSHTM and other members of the consortium to discuss and develop key aspects of the project.<\/p>\n<p>The workshop with stakeholders involved 20 representatives from the community, health sector, and government, including patients, nurses, doctors, laboratory staff, hospital directors and managers. Dr Dimbintsoa Rakotomalala Robinson, a Ph.D. Student at MRCG@LSHTM member of the NIHR GHRG, and Dr Jesus Rodriguez-Manzano, Senior Lecturer in the Section of Adult Infectious Disease at Imperial College, and co-founder and CSO of , led a live demonstration of \u201cDragonfly\u201d digital diagnostics, the technology developed at Imperial College in partnership with <a href=\"https:\/\/www.protondx.com\/\">ProtonDx<\/a> for the NIHR GHRG.<\/p>\n<div id='gallery-1' class='gallery galleryid-574 gallery-columns-3 gallery-size-large'><figure class='gallery-item'>\n\t\t\t<div class='gallery-icon landscape'>\n\t\t\t\t<a href='https:\/\/blogs.imperial.ac.uk\/doid-staff\/2024\/07\/25\/digital-diagnostics-for-african-health-systems-in-the-gambia\/screenshot-2024-07-25-at-15-38-53\/'><img loading=\"lazy\" decoding=\"async\" width=\"640\" height=\"425\" src=\"https:\/\/blogs.imperial.ac.uk\/doid-staff\/files\/2024\/07\/Screenshot-2024-07-25-at-15.38.53-1024x680.png\" class=\"attachment-large size-large\" alt=\"\" aria-describedby=\"gallery-1-577\" \/><\/a>\n\t\t\t<\/div>\n\t\t\t\t<figcaption class='wp-caption-text gallery-caption' id='gallery-1-577'>\n\t\t\t\tA Ph.D. student and members of the NIHR GHRG in visit to Sukuta Health Centre, on June 3, 2024, The Gambia\nCredits: Muhammed Jobe, Digital Content Officer, MRCG@LSHTM\n\t\t\t\t<\/figcaption><\/figure><figure class='gallery-item'>\n\t\t\t<div class='gallery-icon landscape'>\n\t\t\t\t<a href='https:\/\/blogs.imperial.ac.uk\/doid-staff\/2024\/07\/25\/digital-diagnostics-for-african-health-systems-in-the-gambia\/screenshot-2024-07-25-at-15-41-29\/'><img loading=\"lazy\" decoding=\"async\" width=\"640\" height=\"466\" src=\"https:\/\/blogs.imperial.ac.uk\/doid-staff\/files\/2024\/07\/Screenshot-2024-07-25-at-15.41.29-1024x745.png\" class=\"attachment-large size-large\" alt=\"\" aria-describedby=\"gallery-1-578\" \/><\/a>\n\t\t\t<\/div>\n\t\t\t\t<figcaption class='wp-caption-text gallery-caption' id='gallery-1-578'>\n\t\t\t\tDr Dimbintsoa Rakotomalala Robinson and Dr Jesus Rodriguez-Manzano demonstrating the versatile operability of the Dragonfly technology in outdoor settings.\nCredits: Dr Jethro Herberg, Clinical Reader in Paediatric Infectious Diseases at Imperial College London, and member of the NIHR GHRG. \n\t\t\t\t<\/figcaption><\/figure><figure class='gallery-item'>\n\t\t\t<div class='gallery-icon landscape'>\n\t\t\t\t<a href='https:\/\/blogs.imperial.ac.uk\/doid-staff\/2024\/07\/25\/digital-diagnostics-for-african-health-systems-in-the-gambia\/screenshot-2024-07-25-at-15-44-49\/'><img loading=\"lazy\" decoding=\"async\" width=\"640\" height=\"568\" src=\"https:\/\/blogs.imperial.ac.uk\/doid-staff\/files\/2024\/07\/Screenshot-2024-07-25-at-15.44.49-1024x909.png\" class=\"attachment-large size-large\" alt=\"\" aria-describedby=\"gallery-1-579\" \/><\/a>\n\t\t\t<\/div>\n\t\t\t\t<figcaption class='wp-caption-text gallery-caption' id='gallery-1-579'>\n\t\t\t\tEbrima Kuruma, Community Health Worker at Sukuta Heath Centre, and Fatou Sabally, Head of Facility at Bakau Health Centre, sharing their insights and feedback during the workshop\nCredits: Dr Annette Erhart, Malaria Coordinator at MRCG@LSHTM, and member of the member of the NIHR GHRG. \n\t\t\t\t<\/figcaption><\/figure><figure class='gallery-item'>\n\t\t\t<div class='gallery-icon landscape'>\n\t\t\t\t<a href='https:\/\/blogs.imperial.ac.uk\/doid-staff\/2024\/07\/25\/digital-diagnostics-for-african-health-systems-in-the-gambia\/photo-4-1\/'><img loading=\"lazy\" decoding=\"async\" width=\"640\" height=\"303\" src=\"https:\/\/blogs.imperial.ac.uk\/doid-staff\/files\/2024\/07\/PHOTO-4.1-1024x485.jpg\" class=\"attachment-large size-large\" alt=\"\" aria-describedby=\"gallery-1-580\" \/><\/a>\n\t\t\t<\/div>\n\t\t\t\t<figcaption class='wp-caption-text gallery-caption' id='gallery-1-580'>\n\t\t\t\tThe NIHR GHRG discussing with stakeholders in different thematic working groups. \nCredits: Dr Annette Erhart, Malaria Coordinator at MRCG@LSHTM, and member of the member of the NIHR GHRG.\n\t\t\t\t<\/figcaption><\/figure><figure class='gallery-item'>\n\t\t\t<div class='gallery-icon landscape'>\n\t\t\t\t<a href='https:\/\/blogs.imperial.ac.uk\/doid-staff\/2024\/07\/25\/digital-diagnostics-for-african-health-systems-in-the-gambia\/screenshot-2024-07-25-at-15-46-24\/'><img loading=\"lazy\" decoding=\"async\" width=\"640\" height=\"474\" src=\"https:\/\/blogs.imperial.ac.uk\/doid-staff\/files\/2024\/07\/Screenshot-2024-07-25-at-15.46.24-1024x758.png\" class=\"attachment-large size-large\" alt=\"\" aria-describedby=\"gallery-1-581\" \/><\/a>\n\t\t\t<\/div>\n\t\t\t\t<figcaption class='wp-caption-text gallery-caption' id='gallery-1-581'>\n\t\t\t\tDr. Talya Porat (User-Interface Co-Development Lead, from the Dyson School of Design Engineering at Imperial College) and Professor Julie Balen (Health Systems Lead from Canterbury Christ Church University) in a group photo with Sally Bojang and Ida Cham and their children. \nCredits: Professor Aubrey Cunnington, Co-Lead of the NIHR GHRG.\n\t\t\t\t<\/figcaption><\/figure>\n\t\t<\/div>\n\n<p>The stakeholders discussed key aspects of the co-development of digital diagnostics with the research group, including health systems strengthening and policy for device integration, community engagement and involvement, user-interface design, and data integration. These discussions were facilitated by the NIHR GHRG\u2019s ten PhD students, whose research forms the foundation of the project.<\/p>\n<p>The event was featured on local news channels <a href=\"https:\/\/www.facebook.com\/100066580428893\/videos\/1004855447931046\">GRTS<\/a> and <a href=\"https:\/\/www.facebook.com\/QTVGM\/videos\/970490738207673\">QTV<\/a> and participants engaged in interviews with the media.<\/p>\n<p>Professor Aubrey Cunnington, Co-Lead of the NIHR GHRG and Head of Paediatric Infectious Disease Section, discussed the alarming gap in diagnostic access in Africa. Reports from the World Bank and other organizations indicate that more that than 50% of the population lacks access to diagnostics tests, and even when available, access to the essential diagnostics recommended by the WHO is limited. This lack of access hinders effective disease diagnosis and treatment, contributing to the ongoing public health challenges in the African regions.<\/p>\n<figure id=\"attachment_586\" aria-describedby=\"caption-attachment-586\" style=\"width: 640px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"761\" class=\"wp-image-586 size-large\" src=\"https:\/\/blogs.imperial.ac.uk\/doid-staff\/files\/2024\/07\/Screenshot-2024-07-25-at-15.52.29-1024x761.png\" alt=\"\" \/><figcaption id=\"caption-attachment-586\" class=\"wp-caption-text\">Professor Aubrey Cunnington, Imperial College, interviewed by local media GRTS and QTV on the rationale of the NIHR GHRG project<\/figcaption><\/figure>\n<p>\u201cIf we don\u2019t have diagnostics tests, we don\u2019t know what is causing someone\u2019s illness, and then we don\u2019t know what\u2019s the best treatment to give them, so it is almost like the nurses and doctors wearing a blindfold when they are trying to work out what\u2019s wrong with their patients\u201d Professor Aubrey Cunnington, Imperial College London.<\/p>\n<figure id=\"attachment_587\" aria-describedby=\"caption-attachment-587\" style=\"width: 300px\" class=\"wp-caption alignleft\"><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"168\" class=\"wp-image-587 size-medium\" src=\"https:\/\/blogs.imperial.ac.uk\/doid-staff\/files\/2024\/07\/PHOTO-7-300x168.jpg\" alt=\"\" \/><figcaption id=\"caption-attachment-587\" class=\"wp-caption-text\">Dr Mustapha Bittaye, Chief Medical Director of Edward Francis Small Teaching Hospital, speaks with the local media about the significance and impact of of the NIHR GHRG research for the Gambian health systems.<\/figcaption><\/figure>\n<p>Dr Mustapha Bittaye, Chief Medical Director of Edward Francis Small Teaching Hospital in Banjul, stated that \u201cthe research that has been done is going to be very helpful for Africa as the technology developed by the NIHR GHRG can make difficult diagnoses very simple at the point-of-care\u201d. Dr. Bittaye also remarked that the collaboration with the NIHR-funded researchers can enhance local capacity, and Gambian early career-researchers are encouraged to work with the NIHR Group to develop skills and become independent in the development and use of new diagnostics.<\/p>\n<p>The stakeholders discussed key aspects of the co-development of digital diagnostics with the research group, including health systems strengthening and policy for device integration, community engagement and involvement, user-interface design, and data integration. These discussions were facilitated by the NIHR GHRG\u2019s ten PhD students, whose research forms the foundation of the project.<\/p>\n<p>The NIHR GHRG gathered valuable feedback on feasibility, usability, and potential improvements to inform the next stage of prototype evaluation and development, planned over the next two years of the project. The workshop was a success and an invaluable opportunity for of learning and sharing, against the beautiful backdrop of The Gambia.<\/p>\n<p>Funding: The workshop was funded by the Research England International Science Partnership Fund (ISPF) 2023\/2024 Global Development Hub ODA Project Accelerator through Imperial College London (G28643). The NIHR GHRG on Digital Diagnostics for African Health Systems is funded by the NIHR (134694) using UK aid from the UK Government to support global health research. The views expressed in [this publication] are those of the author(s) and not necessarily those of the NIHR or the UK government<\/p>\n<p>&#8212;<\/p>\n<p><strong>About the NIHR GHRG on Digital Diagnostics for African Health Systems<\/strong><\/p>\n<p>Established in August 2022, the NIHR Global Health Research Group on Digital Diagnostics for African Health Systems aims to develop an evidence-base to support the development, implementation, and impact of digital diagnostics technology in African health systems, and training a cohort of African Digital Diagnostics Fellows who will evaluate the impact of and develop further digital diagnostics technology.<\/p>\n<p>The NIHR GHRG brings together a large international and interdisciplinary group of researchers and experts, from 16 different organizations based in 8 countries, between Africa, the UK and Netherlands, and it is led by Professor Aubrey Cunnington, Head of Section and Professor of Paediatric Infectious Disease at Imperial College London, and Professor Halidou Tinto, Regional Director of the Clinical Research Unit of Nanoro (CRUN) at the Institut de Recherche en Sciences de la Sant\u00e9 (IRSS) in Burkina Faso.<\/p>\n<p><strong>About the Digital Diagnostic Technologies<\/strong><\/p>\n<p>As part of the NIHR GHRG programme, Dr Jesus Rodriguez-Manzano and Professor Pantelis Georgiou\u2019s Imperial College and <a href=\"https:\/\/www.protondx.com\">ProtonDx<\/a> teams, are working on the development of portable, rapid diagnostic solutions, including <a href=\"https:\/\/www.protondx.com\/products\/dragonfly\">Dragonfly<\/a> and Lacewing, for the detection of asymptomatic malaria infections and associated plasmodium species. These solutions provide high level analytical performance equivalent to Nucleic Acid Amplification Tests (NAATS), in a simple to use, cloud connected solution that can be performed without skilled staff, laboratory infrastructure or cold chain requirements.<\/p>\n<figure id=\"attachment_588\" aria-describedby=\"caption-attachment-588\" style=\"width: 300px\" class=\"wp-caption alignleft\"><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"169\" class=\"wp-image-588 size-medium\" src=\"https:\/\/blogs.imperial.ac.uk\/doid-staff\/files\/2024\/07\/PHOTO-8-Setup-with-kits-and-panel-300x169.png\" alt=\"\" \/><figcaption id=\"caption-attachment-588\" class=\"wp-caption-text\">The \u201cDragonfly\u201d digital diagnostics platform set up with kits and panel<br \/>Credits: ProtonDX Team, partner of the NIHR GHRG<\/figcaption><\/figure>\n<p><strong>Dragonfly<\/strong><\/p>\n<p>Dragonfly, led by Dr Rodriguez-Manzano, incorporates power-free, magnetic nanoparticle-based nucleic acid purification and lyophilized colorimetric Loop Mediated Isothermal Amplification (RT-LAMP) technology, providing sample-to-result outcomes in less than 30 minutes. In contrast to conventional molecular diagnostics, Dragonfly is easy to perform, requiring only a small battery-powered, portable heat block. The operational and analytical performance of Dragonfly for malaria detection in fingerprick blood has been recently evaluated as part of two studies involving over 600 patients in collaboration with teams in The Gambia and Burkina Faso.<\/p>\n<p><strong>Lacewing<\/strong><\/p>\n<p>Led by Professor Pantelis Georgiou and Dr Nicolas Moser, Lacewing is an automated, portable, state-of-the-art Lab-on-Chip electrochemical sensing technology, which integrates LAMP based molecular approaches and cloud-based surveillance. The platform uniquely allows for high analytical performance and high speed without the need for bulky equipment and centralised laboratory infrastructure. The Lacewing technology is envisioned to be targeted to untrained users, and compatible with remote areas of low-resource settings. Lacewing has already been demonstrated for a range of targets including SARS-CoV2, dengue, colistin resistance and transcriptomic signatures to detect bacterial and viral infections, and it has now been adapted for malaria detection.<\/p>\n<p><em>Credits: The event was organized by Francesca Piffer, Project Manager at Imperial College London of the NIHR Global Health Research Group on Digital Diagnostics for African Health Systems, in collaboration with MRCG@LSYTM Administration, Communication and Finance teams\u2013including Lucene Ahadzie, Isatou Foon, Amat Cham, Dr Shiloe Marie Mokay-Rinke, Alhassan Drammeh, and Mohammed Jobe\u2013 and with Dr Annette Erhart, MRCG@LSHTM Malaria Coordinator, and Professor Umberto D\u2019Alessandro, Director of the MRC Unit The Gambia. <\/em><\/p>\n<p><em>The report was written by Francesca Piffer, Project Manager of the NIHR GHRG. <\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>From 3-7 June 2024, the NIHR Global Health Research Group (NIHR GHRG) on Digital Diagnostics for African Health Systems convened an in-person workshop at Cape Point, The Gambia. The workshop aimed to gather insights from local stakeholders on the potential and application of portable digital diagnostics within Gambian health systems, and to enhance understanding and [&hellip;]<\/p>\n","protected":false},"author":1382,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[48173],"tags":[],"class_list":["post-574","post","type-post","status-publish","format-standard","hentry","category-uncategorised"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Digital Diagnostics for African Health Systems in The Gambia - DoID Staff Blog<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/blogs.imperial.ac.uk\/doid-staff\/2024\/07\/25\/digital-diagnostics-for-african-health-systems-in-the-gambia\/\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Digital Diagnostics for African Health Systems in The Gambia - DoID Staff Blog\" \/>\n<meta property=\"og:description\" content=\"From 3-7 June 2024, the NIHR Global Health Research Group (NIHR GHRG) on Digital Diagnostics for African Health Systems convened an in-person workshop at Cape Point, The Gambia. 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