Latest publications: July and August 2025

Congratulations to members of the Department who have recently had their research findings published. Here’s our round-up of the latest publication successes.


To ensure the quality and accuracy of the information published on this blog, we source our data directly from Symplectic. Our reports are generated on a monthly basis, which means there may be a delay in publicising some publications.

Title Canonical journal title Publication type Authors OR Authors/Contributors Publication date
<i>BCR::ABL1</i>‐Positive Acute Myeloid Leukemia American Journal of Hematology Journal article Canali A, Rieu J, Lapierre L, Bain BJ 01/07/2025
2025 European LeukemiaNet recommendations for the management of chronic myeloid leukemia Leukemia Journal article Apperley JF, Milojkovic D, Cross NCP, Hjorth-Hansen H, Hochhaus A, Kantarjian H, Lipton JH, Malhotra H, Niederwieser D, Radich J, Rousselot P, Saussele S, Schiffer CA, Silver R, Soverini S, Stenke L, Turkina A, Casado LF, Castagnetti F, Cervantes F, Clark RE, Cortes J, Deininger M, Hughes TP, Janssen J, Jiang Q, Kim D-W, Larson RA, Mahon FX, Mauro M, Mayer J, Nicolini FE, Pane F, Rea D, Richter J, Rosti G, Saglio G, Hehlmann R 01/08/2025
A Method for Comparing Proteins Measured in Serum and Plasma by Olink Proximity Extension Assay Molecular and Cellular Proteomics Journal article Shraim R, Diorio C, Canna SW, Macdonald-Dunlop E, Bassiri H, Martinez Z, Mälarstig A, Abbaspour A, Teachey DT, Lindell RB, Behrens EM 01/07/2025
A novel in vitro model of trauma-induced endotheliopathy provides a platform for studying mechanisms of coagulopathy Blood: Vessels, Thrombosis & Hemostasis Journal article Abu-Hanna J, Xu G, Morrow GB, Timms L, Akbar N, Laffan M, Choudhury RP, Curry N 01/07/2025
Acanthocytosis contributes to the diagnosis of the McLeod syndrome American Journal of Hematology Journal article Layton DM, Bain BJ 01/07/2025
Advances in the treatment of ANCA-associated vasculitis Nature Reviews Rheumatology Journal article Trivioli G, Casal Moura M, Kronbichler A, Smith RM, Terrier B, McAdoo S, Jones RB, Merkel PA, Jayne DRW 01/07/2025
Annexin A2 interferes with complement regulation within the glomerulus. Journal of Biological Chemistry Journal article Renner B, Laskowski J, Poppelaars F, Whelan R, Milliron K, Petr V, Blaine J, Ozekin Y, Ferreira VP, Pickering MC, Schmidt CQ, Hajjar K, Davidson A, Thurman JM 30/08/2025
Anti-PF4 disorders: pathogenesis, diagnosis, and treatment British Journal of Haematology Journal article Preece MV, Pathak DV, Laffan M, Jayakody Arachchillage D 01/07/2025
Apoptosis-targeting BH3 mimetics: transforming treatment for patients with acute myeloid leukaemia. Nature Reviews Clinical Oncology Journal article Glaviano A, Weisberg E, Lam HY, Tan DJJ, Innes AJ, Ge Y, Lai CE, Stock W, Glytsou C, Smit L, Yoshida T, Zhang TY, Kennedy VE, Smith BD, Mercher T, de Botton S, Diana P, Konopleva M, Mauro MJ, Griffin JD, DiNardo CD, Kumar AP 01/09/2025
Asciminib remained superior vs bosutinib in late-line CML-CP after nearly 4 years of follow-up in ASCEMBL Blood Advances Journal article Mauro MJ, Minami Y, Hochhaus A, Lomaia E, Voloshin S, Turkina A, Kim D-W, Apperley JF, Cortes JE, Abdo A, Fogliatto LM, Kim DDH, le Coutre P, Saussele S, Annunziata M, Hughes TP, Chaudhri N, Chee L, García-Gutiérrez V, Sasaki K, Boquimpani C, Kapoor S, Espurz N, Dhamal V, Rea D 26/08/2025
Association of coagulation dysfunction with thrombosis, bleeding and mortality in patients supported by veno-venous extracorporeal membrane oxygenation for viral pneumonia. Journal of Thrombosis and Haemostasis Journal article Arachchillage DJ, Gaspar M, Gierula M, Kamani F, Rosenberg A, Mobayen G, Karawitage N, Vinayagam S, Laffan M, Ledot S, Ahnström J 26/08/2025
Cardiac involvement in eosinophilic granulomatosis with polyangiitis Current Cardiology Reports Journal article Srikantharajah M, Gopalan D, Wilson-Morkeh H, Siddiqui S, McAdoo SP, Youngstein T 09/07/2025
Chemotaxis overrides the killing response in alloreactive CTLs, providing vascular immune privilege during cellular rejection Journal of Clinical Investigation Journal article Barba T, Oberbarnscheidt M, Franck G, Gao C, This S, Rabeyrin M, Roufosse C, Moran L, Koenig A, Mathias V, Saison C, Dubois V, Pallet N, Anglicheau D, Lamarthée B, Hertig A, Morelon E, Hot A, Paidassi H, Defrance T, Nicoletti A, Duong Van Huyen J-P, Xu-Dubois Y-C, Lakkis FG, Thaunat O 15/07/2025
Clinical and Histologic Predictors of Kidney Outcomes in C3 Glomerulopathy and Idiopathic Membranoproliferative GN Clinical Journal of the American Society of Nephrology Journal article Ghaddar M, Caravaca-Fontán F, Praga M, Fernández-Juárez G, Lomax-Browne HJ, Cook HT, Daina E, Noris M, Remuzzi G, Induruwage D, Zhu B, Pickering MC, Barbour SJ 01/08/2025
Digital pathology and image analysis of p53 biomarker in lymphomas using two algorithms: correlation with genotype and visual inspection. Journal of Clinical Pathology Journal article Naik A, Kanzaria A, Chen X, Kaur N, Ho C-CJ, Smith SD, Gopal AK, Shadman M, Naresh KN 25/08/2025
Enhancer heterogeneity in acute lymphoblastic leukemia drives differential gene expression in patients Blood Journal article Smith A, Denny NDR, Chahrour C, Sharp K, Arachi M, Dopico-Fernandez AM, Elliott N, Harman J, Jackson T, Geng H, Smith O, Bond J, Roberts I, Stam RWW, Crump N, Davies J, Roy A, Milne TA
Evaluating <scp>IL1RA</scp>‐Autoantibodies Across <scp>SARS</scp>‐<scp>CoV</scp>‐2‐Related Diseases Scandinavian Journal of Immunology Journal article Behere A, Hallberg P, Cederholm A, Cavalli M, Yalcinkaya A, Bastard P, Puel A, Casanova J, Wadelius M, Brodin P, Landegren N 01/07/2025
Executive summary: the 2025 British Society for Rheumatology management recommendations for ANCA-associated vasculitis Rheumatology Journal article Biddle K, Jade J, Wilson-Morkeh H, Adikari M, Al Yaghchi C, Anastasa Z, Basu N, Brogan P, Chanouzas D, Dass S, D’Cruz D, Martinez Del Pero M, Dhillon E, Ducker G, Griffin S, Hollick RJ, Jackson D, King C, Marlais M, Mason A, McAdoo S, Mewar D, Mooney J, Ntatsaki E, Pearce F, Rhodes B, Rupani H, Salama A, Siddiqui S, Smith R, Harper L, Joyce C, McLaren Z, Jones C, Merrison K, Roddy E, Saha P, Williams E, Rose-Parfitt E, Mewar D, Cotton C, Compeyrot-Lacassagne S, Kuttikat A, Jayasekera H, Ciurtin C 01/08/2025
Fifth edition WHO classification: mature B-cell neoplasms Journal of Clinical Pathology Journal article Naresh KN, Karube K, Borges A, Cheuk W, Gujral S, Sayed S, Sohani A, Lazzi S, Ott G, Du M-Q, Leoncini L, Chan JKC
Fifth edition WHO classification: precursor lymphoid neoplasms, acute leukaemias of mixed or ambiguous lineage, myeloid/lymphoid neoplasms, and histiocytic and dendritic cell neoplasms, including strategies for application in resource-limited settings Journal of Clinical Pathology Journal article Tembhare P, Chen X, Chan JKC, Wood B, Naresh KN 01/08/2025
Frailty Impact on Kidney Transplantation in Older People (KTOP) Kidney International Reports Journal article Thind AK, Willicombe M, Dor FJMF, Johansson L, Thomas N, Rule A, Goodall D, Levy S, Brice S, Ospalla D, Wellsted D, Brown EA 01/08/2025
Harnessing the immunotherapeutic potentials of gamma delta T cells against hematological malignancies HemaSphere Journal article Agbuduwe C, Maher J, Anderson J 01/08/2025
Hematopoietic Stem Cell (HSC) Graft Cryopreservation Effects on Outcomes of Patients with Hematologic Malignancies: the Multicenter United Kingdom Experience During the COVID-19 Pandemic Transplantation and Cellular Therapy Journal article Barkauskiene R, Pryce A, Pearce R, Snowden JA, Malladi R, Potter V, Lee J, Wilson M, Cooper N, Apperley JF, Anthias C, Pagliuca A, Pawson R, Danby R 01/08/2025
Hereditary spherocytosis due to an SPTA1 nonsense mutation coinherited with α spectrinLELY in trans American Journal of Hematology Journal article Molina‐Arrebola M, Bain BJ 27/07/2025
Human neutrophil-derived extracellular vesicles induce renal endothelial inflammation in critical illness: an ex vivo investigation. British Journal of Anaesthesia Journal article Stephens JR, Iki Y, Yasuda T, Brown E, Tsiridou D, Green A, Patel P, Waheed U, Stümpfle R, Ratnayake A, Sarathchandra P, Cheng X, Gordon A, Wakabayashi K, O’Dea K, Tam FWK, Brett SJ, Takata M, Soni S 27/08/2025
Imbalanced TGFβ signalling and autophagy drive erythroid priming of hematopoietic stem cells in β-thalassemia Nature Communications Journal article Lidonnici MR, Chianella G, Mende N, Bastos HP, Barcella M, Merelli I, Storto M, Romeo V, Tiboni F, Scaramuzza S, Rossi C, Raggi L, Aprile A, Crippa S, Iskander D, Roberts I, Karamiditris A, Keith J, Lechauve C, Weiss MJ, Wilson NK, Göttgens B, Bernardo ME, Ciceri F, Aiuti A, Marktel S, Laurenti E, Ferrari G 01/07/2025
Immune development differs between preterm newborns fed mothers’ own milk and donor milk iScience Journal article Tan Z, Zhong W, Danielsson H, Arzoomand A, Lakshmikanth T, Chen Q, Mikes J, Wang J, Chen Y, James A, Nilsson AK, Elfvin A, Brusselaers N, Portlock T, Lundgren P, Sävman K, Wackernagel D, Hansen-Pupp I, Ley D, Uhlén M, Hellström A, Brodin P 01/07/2025
Intrapartum management of anticoagulation in a pregnant woman with acute cerebral venous sinus thrombosis undergoing vaginal delivery Obstetric Medicine Journal article Park E, Dhanjal M, Gupta S, Millar C, Primrose N, Sodhi V, Frise C 31/07/2025
Lymph node fibroblast phenotypes and immune crosstalk regulated by podoplanin activity Cell Reports Journal article Makris S, Hari-Gupta Y, Cantoral-Rebordinos JA, Martinez VG, Horsnell HL, Benjamin AC, Cinti I, Jovancheva M, Shewring D, Nguyen N, de Winde CM, Denton AE, Acton SE 22/07/2025
MDS/MPN with SF3B1 mutation and thrombocytosis but without ring sideroblasts American Journal of Hematology Journal article Hazarika B, Bain BJ 22/08/2025
Misdirected yet intact TREX1 exonuclease activity causes human cerebral and systemic small vessel disease Brain: a journal of neurology Journal article McGlasson S, Reid K, Klingseisen A, Rioux B, Chauvin S, Miner CA, Holley J, Forbes D, Geary B, Kimber J, Wood K, Roufosse C, Smith C, Kavanagh D, Miner J, Hunt DPJ 01/08/2025
Non-invasive diagnosis of kidney allograft rejection Journal of the American Society of Nephrology Journal article Cardoso De Aguiar R, Willicombe M, Roufosse C 06/08/2025
Not all hereditary iron overload is hemochromatosis: a case of hereditary xerocytosis unmasked by blood smear morphology American Journal of Hematology Journal article Molina‐Arrebola M, Bain BJ 09/07/2025
Off-the-shelf dual CAR-iNKT cell immunotherapy eradicates medullary and leptomeningeal high-risk KMT2A-rearranged leukemia. Blood Journal article Ren H, Elliott N, Lye B, Sharif Shohan MU, Cross JW, Field LM, Ponnusamy K, Rice S, Jackson T, Leontari I, El Ouazzani N, Thomas R, Inglott S, Bartram J, Smith O, Bond J, Roberts I, Halsey C, Bashford-Rogers R, Milne TA, Roy A, Karadimitris A 03/09/2025
Partial nuclear extrusion in chronic lymphocytic leukemia observed to be an in vitro artefact American Journal of Hematology Journal article Chatila R, Beziat G, Pirovano L, Bouyssie C, Rieu J, Bain BJ 22/08/2025
Perceived barriers to peritoneal dialysis utilization amongst South Asian nephrologists Peritoneal Dialysis International Journal article Bhargava V, Meena P, Agrawaal KK, Wijayaratne D, Kar S, Qayyum A, Sultana A, Shiham I, Brown E, Mushahar L 23/07/2025
Point-of-care lung ultrasound assessment of positional changes in COVID-19 ARDS in intensive care: a case report and review of the literature Physiological Reports Journal article Koca O, Koksal G 01/08/2025
Porcine respiratory coronavirus as a model for acute respiratory disease: mechanisms of different infection outcomes Journal of Immunology Journal article Sedaghat-Rostami E, Carr BV, Yang L, Keep S, Lean FZX, Atkinson I, Fones A, Paudyal B, Kirk J, Vatzia E, Gubbins S, Bickerton E, Briggs E, Núñez A, McNee A, Moffat K, Freimanis G, Rollier C, Muir A, Richard AC, Angelopoulos N, Gerner W, Tchilian E 01/07/2025
PROM1/CD133 MARKS A PROLIFERATIVE STEM CELL LIKE POPULATION OF BLASTS IN KMT2A REARRANGED INFANT ALL Blood Advances Journal article Cross JW, Field LM, Smith A, Neil E, Hamer L, Jackson T, Elliott N, Rice S, Crump N, Harman J, Ling RE, Wu Q, El Ouazzani N, Thomas R, Inglott S, Bartram J, Smith O, Bond J, Roberts I, Milne TA, Roy A 11/09/2025
Proteomic profiling of the large-vessel vasculitis spectrum identifies shared signatures of innate immune activation and stromal remodelling Arthritis & Rheumatology Journal article Maughan R, Macdonald-Dunlop E, Haroon-Rashid L, Sorensen L, Chaddock N, Masters S, Porter A, Peverelli M, Pericleous C, Hutchings A, Robinson J, Youngstein T, Luqmani R, Mason J, Morgan A, Peters J 01/07/2025
Questions and Caveats in Antigen-Defined Membranous Nephropathy Journal of the American Society of Nephrology Journal article Andeen NK, Kung VL, Avasare RS, Barbour S, Griffith M, Bissonnette MLZ, Roufosse C 01/08/2025
Refining the risk stratification in advanced-stage classical Hodgkin lymphoma: a critical analysis of clinical prediction models British Journal of Haematology Journal article Koca O, Eskazan AE 22/08/2025
Renal Pathology Society/International Kidney and Monoclonal Gammopathy Research Group consensus on pathologic definitions and terminology of monoclonal gammopathy–associated kidney lesions Kidney International Journal article Nasr SH, Royal V, Best Rocha A, Büttner-Herold M, Roufosse C, Bridoux F, Ismail W, Bu L, Cornell LD, Dendooven A, Gupta RK, Hara S, Javaugue V, Kozakowski N, Kudose S, Méndez GP, Oliver K, Picken MM, Santoriello D, Sethi S, Shimizu A, Singh G, Stokes MB, Wang S-X, Leung N, Markowitz GS, D’Agati VD 01/08/2025
Role of Fibroblast-Immune Crosstalk in Kidney, Lung, and Skin Tertiary Lymphoid Structures. Immunological Reviews Journal article Cross A, Shelley J, Newman R, Strid J, Denton AE 01/09/2025
Sézary syndrome—eosinophilia explained by a blood film American Journal of Hematology Journal article Soeterik MTA, Janssen J, Budel LM, Langerak AW, Sandberg Y, Bain BJ 01/08/2025
Splenic EBV-positive inflammatory follicular dendritic cell sarcoma with fibroblastic/myoid immunophenotype in a patient with EBV-negative diffuse large B cell lymphoma Journal of Clinical Pathology Journal article Love JE, Naresh KN 18/09/2025
Systems analysis of clinical malaria reveals proteomic perturbation and innate-adaptive crosstalk linked to disease severity Immunity Journal article Lautenbach MJ, Wyss K, Yman V, Foroogh F, Satarvandi D, Mousavian Z, Sondén K, Wang J, Álvez MB, Bergström S, Nilsson P, Edfors F, Brodin P, Uhlén M, Sundling C, Färnert A 01/08/2025
Taurine transport is a critical modulator of ionic fluxes during NLRP3 inflammasome activation Cell Reports Journal article Rossi-Smith P, Kim J, Skirlo K, Ferris T, Green J, Stek C, Huse K, Mortimer P, Olona A, Wieder C, Moseki R, Silva Dos Santos M, MacRae J, Sriskandan S, Ebbels T, Wilkinson R, Denton A, Matheson N, Anand P, Meintjes G, Thomas D, Lai P-J 18/09/2025
Temporal multi-omic analysis of COVID-19 in end-stage kidney disease Cell Genomics Journal article Stephenson E, Macdonald-Dunlop E, Dratva L, Lindeboom RGH, Tuong ZK, Tun WM, Kretschmer L, Buang NB, Ballereau S, Cabantaus M, Peñalver A, Prigmore E, Ferdinand JR, Stewart BJ, Gisby J, Malik T, Medjeral- Thomas N, Prendecki M, McAdoo S, Portet A, Willicombe M, Sandhu E, Pickering MC, Botto M, Teichmann SA, Haniffa M, Clatworthy MR, Thomas DC, Peters J 13/08/2025
The 2025 British Society for Rheumatology management recommendations for ANCA-associated vasculitis Rheumatology Journal article Biddle K, Jade J, Wilson-Morkeh H, Adikari M, Yaghchi CA, Anastasa Z, Basu N, Brogan P, Chanouzas D, Dass S, D’Cruz D, Del Pero MM, Dhillon E, Ducker G, Griffin S, Hollick RJ, Jackson D, King C, Marlais M, Mason A, McAdoo S, Mewar D, Mooney J, Ntatsaki E, Pearce F, Rhodes B, Rupani H, Salama A, Siddiqui S, Smith R, Harper L, Joyce C, McLaren Z, Jones C, Merrison K, Roddy E, Saha P, Williams E, Rose-Parfitt E, Mewar D, Cotton C, Compeyrot-Lacassagne S, Kuttikat A, Jayasekera H, Ciurtin C 01/08/2025
The Significance of the Amino Acid at Position 2561 in the C4 Domain of Von Willebrand Factor. Journal of Thrombosis and Haemostasis Journal article McKinnon TAJ, Liu Y, Gong F, Chion A, Rothery S, Zhang XF, Mobayen G 05/09/2025
Updated recommendations for the treatment of light-chain amyloidosis from the Swiss Amyloidosis Network Swiss Medical Weekly Journal article Rieger MJ, Flammer AJ, Gerull S, Pabst T, Auner HW, Samii K, Hitz F, Mey U, Ballova V, Battegay R, Melli G, Benz D, Yakupoglu Y, Gräni C, Schläger R, Hugelshofer S, Studer A, Oechslin L, Bakula A, Suter TM, Leo-Stickelberger J, Averiamo M, Fehr T, Jung HH, Laptseva N, Manka R, Rüfer A, Schmidt A, Seeger H, Müllhaupt B, Stämpfli SF, De Ramon Ortiz C, Théaudin M, Gerber B, Schwotzer R 17/07/2025