Latest publications: September 2025

Congratulations to members of the Department who have recently had their research findings published. Here’s our round-up of the latest publication successes.


Title Canonical journal title Publication type Authors OR Authors/Contributors Publication date
PROM1/CD133 marks a proliferative stem cell-like population of blasts in KMT2A rearranged infant ALL Blood advances Journal article Cross JW, Field L, Smith A, Neil E, Hamer L, Jackson T, Elliott N, Rice S, Crump N, Harman J, Ling RE, Wu Q, El Ouazzani N, Thomas R, Inglott S, Bartram J, Smith O, Bond J, Roberts I, Milne TA, Roy A 23/09/2025
Altered DNA methylation of the ABO gene is associated with differential plasma levels of von willebrand factor and E‐selectin Transfusion Journal article Lou T, Sugrue JA, Patin E, Quintana‐Murci L, Duffy D, O’Farrelly C 01/09/2025
Anti-glomerular basement membrane disease – treatment standard Nephrology Dialysis Transplantation Journal article McAdoo SP, Pusey CD 18/09/2025
Apoptosis-targeting BH3 mimetics: transforming treatment for patients with acute myeloid leukaemia Nature Reviews Clinical Oncology Journal article Glaviano A, Weisberg E, Lam HY, Tan DJJ, Innes AJ, Ge Y, Lai CE, Stock W, Glytsou C, Smit L, Yoshida T, Zhang TY, Kennedy VE, Smith BD, Mercher T, de Botton S, Diana P, Konopleva M, Mauro MJ, Griffin JD, Dinardo CD, Kumar AP 01/09/2025
Approaches toward understanding human immunity Immunity Journal article Brodin P, Wang F, Zhu B, Hammond T, Lu CP, Wimmers F, Zhernakova A, Liu W, Nadeau K, Prlic M 09/09/2025
Association between COVID-19 vaccine immunogenicity and protection against infection and severe disease in clinically vulnerable patient populations: a systematic review and meta-analysis of observational studies Clinical Microbiology and Infection (CMI) Journal article Danysz M, De Aguiar RC, Pindolia H, Stuart B, Spensley K, Ashmore E, Frumento N, Haouidji-Javaux N, Hutchinson C, Iles R, Lau S, Rolt J, Uwenedi G, Wagg H, Barnes E, Lim SH, Richter A, Willicombe M 01/09/2025
BEAM/ATG or cyclophosphamide/ATG as conditioning regimen in autologous haemopoietic stem cell transplantation for multiple sclerosis: a retrospective analysis of the EBMT autoimmune diseases working party Bone Marrow Transplantation Conference Saccardi R, Ponzano M, Badoglio M, Helbig G, Smilowsky M, Mariottini A, Burman J, Carlson K, Kazmi M, Muraro P, Apperley J, Withers B, Massey J, Varaldo R, Inglese M, Sanz J, Gil-Perotin SG, Sharrack B, Alexander T, Greco R, Snowden J 01/10/2024
Biallelic <i>SH2B3</i> germline variants are associated with a neonatal myeloproliferative disease and multisystemic involvement European Journal of Human Genetics Journal article Leardini D, Flex E, Stieglitz E, Cerasi S, Bertuccio SN, Baccelli F, Kallay K, Kjollerstrom P, Batalha S, Carpentieri G, Pedace L, Ciolfi A, Hammad M, Miranda M, Rojas M, Rao A, Innes AJ, Rudelius M, Santini V, Raddi M, Teh K-H, De Vito R, Yoshimi A, Tartaglia M, Locatelli F, Niemeyer CM, Masetti R 01/09/2025
Clinical Presentation, Treatment Patterns, Burden of Disease and the Association of Proteinuria with Clinical Outcomes in C3 Glomerulopathy and Primary Immune Complex Membranoproliferative Glomerulonephritis: A Systematic Review NEPHRON Journal article Caravaca-Fontán F, Fakhouri F, Pickering MC, Lionikaite V, Baird A, Horneff R, López-Lázaro L, Quintana-Gallardo L, Rich C 19/09/2025
Clinical significance of preleukemic somatic GATA1 mutations in children with Down syndrome Blood Journal article Elliott N, Bhatnagar N, Buck G, Cruz Hernandez D, Perkins K, de Smith AJ, Chaussade A, Nizery L, Metzner M, Garnett C, Norton A, Kennedy A, Chakravorty T, Zhao D, Hanssen L, Hall G, Vyas P, Roberts I 25/09/2025
Epidemiology of peritoneal dialysis exit site infections: Does sex play a role? Peritoneal Dialysis International Journal article Beckwith H, Cepe L, Punzalan S, Ghazy A, Lucisano G, Corbett R, Brown EA 02/09/2025
Health outcomes of women with Gestational Diabetes Mellitus in North West London: a 10-year longitudinal study BMJ Public Health Journal article Goldet G, Dattani R, Pierce B, Ul-Haq Z, Kamalati T, Shah M, Frankel A, Tam F 29/09/2025
Hereditary elliptocytosis resulting from heterozygosity for β spectrin Tandil American Journal of Hematology Journal article Molina‐Arrebola M, Bain BJ 01/09/2025
Injury and local injection and the risk of foot/ankle osteoarthritis:  a case-control study in retired UK male professional footballers Rheumatology Journal article Thanoon AA, Espahbodi S, Ali Shuaib M, Millar B, Duncan A, Bowen CJ, O’Neill TW, Wakefield RJ, Watt F, Walsh DA, Fuller G, Batt ME, Parekh SM, Fernandes GS, Doherty M, Zhang W 22/10/2025
Off-the-shelf dual CAR-iNKT cell immunotherapy eradicates medullary and leptomeningeal high-risk KMT2A-rearranged leukemia Blood Journal article Ren H, Elliott N, Lye B, Sharif Shohan MU, Cross JW, Field LM, Ponnusamy K, Rice S, Jackson T, Leontari I, El Ouazzani N, Thomas R, Inglott S, Bartram J, Smith O, Bond J, Roberts I, Halsey C, Bashford-Rogers R, Milne TA, Roy A, Karadimitris A 03/09/2025
Role of fibroblast-immune crosstalk in kidney, lung, and skin tertiary lymphoid structures Immunological Reviews Journal article Cross A, Shelley J, Newman R, Strid J, Denton AE 01/09/2025
RPS19 and RPL5 Haploinsufficient Models Reveal Divergent Ribosomal Subunit Controls of Fetal Hematopoiesis Journal article Blanc L, Tang Y, Ling T, Mehmood R, Bertrand A, Papoin J, Khan M, Rao R, Xu J, Schulz V, Palis J, Steiner L, Barnes B, Zou Y, Marambaud P, Signer R, Roberts I, Iskander D, Zon L, Bhoopalan S, Weiss M, Lipton J, Gallagher P, Mohandas N, Taylor N, Durand S, Crispino J 26/09/2025
The impact of the Banff v-lesion on rejection classification and outcomes: Insights from a multicenter study American Journal of Transplantation Journal article Wellekens K, Coemans M, Koshy P, Vaulet T, Cleenders E, Debyser T, De Pelsmaeker S, Dubois V, Emonds M-P, Kuypers D, Pagliazzi A, Rabeyrin M, Senev A, Scheffner I, Vanhoutte T, Thaunat O, Roufosse C, Gwinner W, Naesens M 01/09/2025
The significance of the amino acid at position 2561 in the C4 domain of Von Willebrand factor Journal of Thrombosis and Haemostasis Journal article McKinnon TAJ, Liu Y, Gong F, Chion A, Rothery S, Zhang XF, Mobayen G 05/09/2025