Congratulations to members of the Department who have recently had their research findings published. Here’s our round-up of the latest publication successes.
To ensure the quality and accuracy of the information published on this blog, we source our data directly from Symplectic. Our reports are generated on a monthly basis, which means there may be a delay in publicising some publications.
| Title | Canonical journal title | Publication type | Authors OR Authors/Contributors | Publication date |
| A novel in vitro model of trauma-induced endotheliopathy provides a platform for studying mechanisms of coagulopathy | Blood Vessels, Thrombosis & Hemostasis | Journal article | Abu-Hanna J, Xu G, Morrow GB, Timms L, Akbar N, Laffan M, Choudhury RP, Curry N | 01/11/2025 |
| A systems immunology approach to the immune system’s competition for energy with acute physical exercise in elite athletes | Journal of Immunology | Conference | Reitzner SM, Mikes J, Brodin P | 01/11/2025 |
| Anti-glomerular basement membrane disease-treatment standard | Nephrology Dialysis Transplantation | Journal article | McAdoo SP, Pusey CD | 18/09/2025 |
| Apoptosis-targeting BH3 mimetics: transforming treatment for patients with acute myeloid leukaemia | Nature Reviews Clinical Oncology | Journal article | Glaviano A, Weisberg E, Lam HY, Tan DJJ, Innes AJ, Ge Y, Lai CE, Stock W, Glytsou C, Smit L, Yoshida T, Zhang TY, Kennedy VE, Smith BD, Mercher T, de Botton S, Diana P, Konopleva M, Mauro MJ, Griffin JD, Dinardo CD, Kumar AP | 01/09/2025 |
| Association of coagulation dysfunction with thrombosis, bleeding, and mortality in patients supported by veno–venous extracorporeal membrane oxygenation for viral pneumonia | Journal of Thrombosis and Haemostasis | Journal article | Arachchillage DJ, Gaspar M, Gierula M, Kamani F, Rosenberg A, Mobayen G, Karawitage N, Vinayagam S, Laffan M, Ledot S, Ahnström J | 01/12/2025 |
| BEAM/ATG or cyclophosphamide/ATG as conditioning regimen in autologous haemopoietic stem cell transplantation for multiple sclerosis: a retrospective analysis of the EBMT autoimmune diseases working party | Bone Marrow Transplantation | Conference | Greco R, Saccardi R, Ponzano M, Badoglio M, Helbig G, Smilowski M, Mariottini A, Burman J, Carlson K, Kazmi M, Muraro PA, Gabriel I, Withers B, Massey J, Varaldo R, Inglese M, Sanz J, Gil-Perotin S, Sharrack B, Roldan E, Nozzoli C, Signori A, Sormani MP, Alexander T, Snowden JA | 29/09/2025 |
| Biomarkers in the Management of Complement-Mediated Kidney Diseases in the Era of Complement Therapeutics | American Society of Nephrology. Clinical Journal | Journal article | Rizk DV, Dixon BP, Chan M, Cook HT, Frazer-Abel A, Tang SCW | 25/11/2025 |
| Cancer-selective targeting of the NF-κB pathway via GADD45β/MKK7 inhibition: Results from the phase I trial of the first-in-class inhibitor, DTP3, in patients with relapsed or refractory multiple myeloma |
Blood | Conference | Chaidos A, Potolidis D, Cornice J, Auner H, Acton G, Bygrave C, Cook G, Popat R, Davies A, Parrish C, Atta M, Linton K, Smith D, Fox C, McNeish I, Hadley E, Ferrer Martinez Del Peral E, Pellegatti M, Adams N, Chau A, Nnebedum P, Capece D, Verzella D, D’Andrea D, Rekowski J, Yap C, Tornatore L, Franzoso G | 03/11/2025 |
| Continuous indices to assess the phenotypic spectrum of kidney transplant rejection | Nature Communications | Journal article | Vaulet T, Koshy P, Wellekens K, Aubert O, Bottomley C, Callemeyn J, Cleenders E, Coemans M, Cornell L, De Vries APJ, Divard G, Emonds M-P, Florquin S, Haas M, Halloran PF, Kers J, Kuypers D, Muthukumar T, Pagliazzi A, Salvatore S, Thaunat O, Seshan SV, Van Loon E, Vanhoutte T, Bohmig GA, Von Samson-Himmelstjerna FA, Willicombe M, Cherukuri A, Loupy A, Roufosse C, Naesens M | 26/11/2025 |
| Differential autoantibodies to cytokines in unselected patients with immune dysregulation | Journal of Immunology | Conference | Kretzschmar G, Brodin P, Pinero Paez L, Behere A, Johsson A, Gonzales L, Horne A, Palmblad K, Landegren N, Lakshmikanth T | 01/11/2025 |
| Enhanced VLA4-dependent endothelial cell adhesion underpins the higher efficacy of CAR-iNKT over CAR-T cells in limiting leptomeningeal acute leukemia | Blood | Journal article | Leontari I, Ren H, Karaxhuku K, Lye B, Ponnusamy K, Himonas E, Roberts I, Chaidos A, Halsey C, Lo Celso C, Karadimitris A | 03/11/2025 |
| Health outcomes in hospitalised and non-hospitalised individuals after COVID-19, an observational, cross-sectional study | Communications Medicine | Journal article | Nygren-Bonnier M, Svensson-Raskh A, Holmstrom L, Tornberg A, Svensson A, Loewenstein D, Regardt M, Bjornson M, Hallberg C, Kemani M, Mc Allister A, Gustafsson JK, Halvarsson A, Ekman U, Nordstrand L, Guidetti S, Anmyr L, Bragesjo M, Reitan JA, Badinlou F, Dahl O, Akerman E, Villner P, Brodin P, Caidahl K, Stahlberg M, Fedorowski A, Skold M, Runold M, Bruchfeld J, Rydwik E | 04/12/2025 |
| Hereditary spherocytosis due to an SPTA1 nonsense mutation coinherited with α spectrinLELY in trans | American Journal of Hematology | Journal article | Molina‐Arrebola M, Bain BJ | 11/11/2025 |
| High sensitivity measurement of circulating interferon proteins in systemic lupus erythematosus | Clinical and Experimental Rheumatology | Journal article | Huang Y-J, Bottomley CM, Maughan RT, Field A, Leung GHD, Lightstone L, Cairns TD, Turner-Stokes T, Condon MB, Peters JE, Botto M, Pickering MC | 23/12/2025 |
| Investigation and management of thrombocytosis without <i>JAK2</i>, <i>CALR</i> or <i>MPL</i> mutations: A British Society for Haematology Guideline | British Journal of Haematology | Journal article | Godfrey AL, Khan AA, McGregor A, Innes AJ, Altohami M, Cross NCP, Frewin R, Garg M, Green A, Grinfeld J, McLornan DP, Wilson AJ, Harrison CN, Mead AJ, Nangalia J | 04/12/2025 |
| Laboratory practice on detection of antiphospholipid antibodies: UK NEQAS blood coagulation survey-2024 | British Journal of Haematology | Journal article | Arachchillage DJ, Laffan M, Lester W, Kitchen S, Jennings I | 26/08/2025 |
| Longitudinal gut microbial trajectories show differences in early life LPS exposure and IFNγ responses | Journal of Immunology | Conference | Arzoomand A, Lou TE, Sahi M, Rodriguez L, Lakshmikanth T, Bernhardsson A-K, Ohlin M, Mugabo C, Gonzales L, Barcenilla H, Johnson A, Schwenk J, Brodin P | 01/11/2025 |
| Low-density granulocytes in the pathogenesis of inflammatory disease | Journal of Leukocyte Biology | Journal article | Nutley AS, Pisacano N, Prendecki M | 01/11/2025 |
| Mapping the plasma proteomic architecture of systemic lupus erythematosus | Preprint | Leung GHD, Bottomley C, Buang N, Maughan RT, Whittle BJ, Zeidaabadi B, Huang Y-J, Turner-Stokes T, Condon M, Lightstone L, Cairns T, Botto M, Pickering MC, Peters JE | 19/11/2025 | |
| Microbiome-derived bile acid signatures in early life and their association with islet autoimmunity | Nature Communications | Journal article | Lamichhane S, Dickens AM, Buchacher T, Lou T, Charron-Lamoureux V, Kattelus R, Karmacharya P, da Silva LP, Kråkström M, Rasool O, Sen P, Walker C, Patan A, Gentry EC, Zuffa S, Arzoomand A, Lakshmikanth T, Mikeš J, Mebrahtu A, Vatanen T, Raffatellu M, Zengler K, Hyötyläinen T, Xavier RJ, Brodin P, Lahesmaa R, Dorrestein PC, Knip M, Orešič M | 03/12/2025 |
| Non-invasive diagnosis of kidney allograft rejection | Journal of the American Society of Nephrology | Journal article | Cardoso De Aguiar R, Willicombe M, Roufosse C | 01/11/2025 |
| Not all hereditary iron overload is hemochromatosis: a case of hereditary xerocytosis unmasked by blood smear morphology | American Journal of Hematology | Journal article | Molina‐Arrebola M, Bain BJ | 01/11/2025 |
| Osteoarthritis | Medicine (United Kingdom) | Journal article | Vincent TL, Watt FE | 01/12/2025 |
| Pro-coagulant lipids in physiological ratios found in the activated platelet membrane do not impact clot structure or fibrinolysis in purified assays | Journal of Blood Medicine | Journal article | Morgan B, Farleigh Smith L, Costa D, Tyrrell V, Ahnström J, Jenkins P, Collins P, Mutch N, O’Donnell V | 08/11/2025 |
| Significance of the amino acid at position 2561 in the C4 domain of Von Willebrand factor | Journal of Thrombosis and Haemostasis | Journal article | McKinnon TAJ, Liu Y, Gong F, Chion A, Rothery S, Zhang XF, Mobayen G | 01/12/2025 |
| Spatial distribution of surface proteins in single T cells and in T-B cell conjugates | Journal of Immunology | Conference | Forlin R, Wang J, Ivanchenko R, Mikes J, Barcenilla H, Tadepally LK, Brodin P | 01/11/2025 |
| The seven enigmas of SARS-CoV-2: From the past to the future | Journal article | Andreakos E, Arkin L, Bastard P, Bolze A, Borghesi A, Brodin P, Casanova J-L, Casari G, Cobat A, Drolet B, Fellay J, Hsieh EWY, Meyts I, Mogensen TH, Sancho-Shimizu V, Spaan AN, Su HC, Vinh DC, Yatim A, Zhang Q, Zhang S-Y, Abel L, Aiuti A, Al-Muhsen S, Andreakos E, Arias AA, Arkin LM, Feldman HB, Bastard P, Bolze A, Bondarenko A, Borghesi A, Bousfiha AA, Brodin P, Casari G, Christodoulou J, Cobat A, Colobran R, Condino-Neto A, Constantinescu SN, Drolet BA, Dündar M, Espinosa-Padilla S, Fellay J, Flores C, Froidure A, Gorochov G, Hagin D, Halwani R, Hammarström L, Hsieh EWY, Itan Y, Jouanguy E, Kaja E, Lau Y-L, Mansouri D, Maródi L, Meyts I, Mogensen TH, Ng LFP, Novelli A, Novelli G, Okada S, Okamoto K, Ozcelik F, Pan-Hammarström Q, Perez de Diego R, Perlin DS, Puel A, Pujol A, Renia L, Sancho-Shimizu V, Shahrooei M, Shcherbina A, Slaby O, Soler-Palacín P, Spaan AN, Tancevski I, Tangye SG, Tayoun AA, Thorball C, Tiberghien P, Turvey SE, Vinh DC, Zhang Q, Zhang S-Y, Su HC, Casanova J-L | 03/11/2025 | |
| Transitioning of patients from direct acting oral anticoagulant to heparin: impact on laboratory testing | Seminars in Thrombosis and Hemostasis | Journal article | Jayakody Arachchillage D, Vinayagam S, Parsons A, Karawitage N, Laffan M | 13/11/2025 |
| Trial of Pegcetacoplan in C3 Glomerulopathy and Immune-Complex MPGN | New England Journal of Medicine | Journal article | Fakhouri F, Bomback AS, Ariceta G, Delmas Y, Dixon BP, Gale DP, Greenbaum LA, Han SH, Isbel N, Le Quintrec M, Licht C, Mastrangelo A, Mizuno M, De Holanda MIN, Pickering MC, Remuzzi G, Van De Kar N, Vivarelli M, Walker PD, Wallace D, Zecher D, Francois C, Deschatelets P, Li L, Wang Z, Abad-Franch L, Kinnman N, Lopez-Lazaro L, Szamosi J, Nester CM | 04/12/2025 |