{"id":5033,"date":"2025-01-01T07:00:48","date_gmt":"2025-01-01T07:00:48","guid":{"rendered":"https:\/\/blogs.imperial.ac.uk\/imperial-medicine\/?p=5033"},"modified":"2024-12-20T11:12:47","modified_gmt":"2024-12-20T11:12:47","slug":"flemings-final-flourish","status":"publish","type":"post","link":"https:\/\/blogs.imperial.ac.uk\/imperial-medicine\/2025\/01\/01\/flemings-final-flourish\/","title":{"rendered":"Fleming\u2019s Final Flourish"},"content":{"rendered":"<p><img loading=\"lazy\" decoding=\"async\" width=\"1181\" height=\"660\" class=\"size-full wp-image-5034 aligncenter\" src=\"https:\/\/blogs.imperial.ac.uk\/imperial-medicine\/files\/2024\/12\/St-Marys-Campus.png\" alt=\"\" \/><\/p>\n<p><strong><a href=\"https:\/\/profiles.imperial.ac.uk\/john.tregoning\">Professor John Tregoning<\/a>, Professor of Vaccine Immunology in the <a href=\"https:\/\/www.imperial.ac.uk\/infectious-disease\/\">Department of Infectious Disease<\/a>, explores the legacy of Sir Alexander Fleming and the urgent fight against antimicrobial resistance. From the historic discovery of penicillin at St Mary\u2019s Medical School to the ambitious Fleming Initiative, Professor Tregoning discusses how a groundbreaking new centre aims to tackle one of the greatest challenges in modern medicine.<\/strong><\/p>\n<hr \/>\n<p style=\"font-weight: 400\"><span class=\"TextRun SCXW1759524 BCX4\" lang=\"EN-GB\" xml:lang=\"EN-GB\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW1759524 BCX4\">If you were watching the <\/span><\/span><a class=\"Hyperlink SCXW1759524 BCX4\" href=\"https:\/\/www.rigb.org\/christmas-lectures\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"TextRun Underlined SCXW1759524 BCX4\" lang=\"EN-GB\" xml:lang=\"EN-GB\" data-contrast=\"none\"><span class=\"NormalTextRun SCXW1759524 BCX4\" data-ccp-charstyle=\"Hyperlink\">R<\/span><span class=\"NormalTextRun SCXW1759524 BCX4\" data-ccp-charstyle=\"Hyperlink\">oyal <\/span><span class=\"NormalTextRun SCXW1759524 BCX4\" data-ccp-charstyle=\"Hyperlink\">I<\/span><span class=\"NormalTextRun SCXW1759524 BCX4\" data-ccp-charstyle=\"Hyperlink\">nstitution (RI)<\/span><span class=\"NormalTextRun SCXW1759524 BCX4\" data-ccp-charstyle=\"Hyperlink\"> Christmas <\/span><span class=\"NormalTextRun SCXW1759524 BCX4\" data-ccp-charstyle=\"Hyperlink\">L<\/span><span class=\"NormalTextRun SCXW1759524 BCX4\" data-ccp-charstyle=\"Hyperlink\">ecture<\/span><span class=\"NormalTextRun SCXW1759524 BCX4\" data-ccp-charstyle=\"Hyperlink\">s<\/span><\/span><\/a><span class=\"TextRun SCXW1759524 BCX4\" lang=\"EN-GB\" xml:lang=\"EN-GB\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW1759524 BCX4\"> with Dr Chris van <\/span><span class=\"NormalTextRun SpellingErrorV2Themed SCXW1759524 BCX4\">Tulleken<\/span><span class=\"NormalTextRun SCXW1759524 BCX4\">,<\/span><span class=\"NormalTextRun SCXW1759524 BCX4\"> you will have seen two plates of food disintegrate into a mushy goo<\/span><span class=\"NormalTextRun SCXW1759524 BCX4\">. This was filmed at <\/span><span class=\"NormalTextRun SCXW1759524 BCX4\">the <\/span><a href=\"https:\/\/blogs.imperial.ac.uk\/imperial-medicine\/2024\/07\/03\/st-marys-history-infectious-disease\/\"><span class=\"NormalTextRun SCXW1759524 BCX4\">St Mary\u2019s <\/span><span class=\"NormalTextRun SCXW1759524 BCX4\">M<\/span><span class=\"NormalTextRun SCXW1759524 BCX4\">edical <\/span><span class=\"NormalTextRun SCXW1759524 BCX4\">S<\/span><span class=\"NormalTextRun SCXW1759524 BCX4\">chool<\/span><\/a><span class=\"NormalTextRun SCXW1759524 BCX4\"> Building in Paddington, London<\/span><span class=\"NormalTextRun SCXW1759524 BCX4\">. In fact<\/span><span class=\"NormalTextRun SCXW1759524 BCX4\">,<\/span><span class=\"NormalTextRun SCXW1759524 BCX4\"> it was<\/span> <span class=\"NormalTextRun SCXW1759524 BCX4\">probably<\/span><span class=\"NormalTextRun SCXW1759524 BCX4\"> the<\/span><span class=\"NormalTextRun SCXW1759524 BCX4\"> last ever <\/span><span class=\"NormalTextRun SCXW1759524 BCX4\">experiment done<\/span><span class=\"NormalTextRun SCXW1759524 BCX4\"> in this hallowed building. In some ways it seems <\/span><span class=\"NormalTextRun SCXW1759524 BCX4\">appropria<\/span><span class=\"NormalTextRun SCXW1759524 BCX4\">te that<\/span><span class=\"NormalTextRun SCXW1759524 BCX4\"> it involved mould. St Mary\u2019s will always be famous as the site of where Sir A<\/span><span class=\"NormalTextRun SCXW1759524 BCX4\">lexander Fleming performed his breakthrough studies. <\/span><span class=\"NormalTextRun SCXW1759524 BCX4\">Or as he modestly put it: <\/span><span class=\"NormalTextRun SCXW1759524 BCX4\">\u2018revolutionize all m<\/span><span class=\"NormalTextRun SCXW1759524 BCX4\">edicine by discovering the world\u2019s first<\/span> <span class=\"NormalTextRun SCXW1759524 BCX4\">antibiotic<\/span><span class=\"NormalTextRun SCXW1759524 BCX4\">\u2019<\/span><span class=\"NormalTextRun SCXW1759524 BCX4\">.<\/span><\/span><span class=\"EOP SCXW1759524 BCX4\" data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:120,&quot;335559740&quot;:276}\">\u00a0<\/span><\/p>\n<p><!--more--><\/p>\n<p><span data-contrast=\"auto\">The story of Fleming and his contaminated plates has often been retold. Basically, his lab was a bit of a dive; he hadn\u2019t tidied up before going on his summer holiday and he got contamination on his bacterial growth studies. For some reason best known to him, rather than saying \u2018oh no, I\u2019ve ruined my experiment\u2019, he said, \u2018that\u2019s curious\u2019, and isolated the mould juice that could kill bacteria. The story goes on to tell how the mould spores came from the Fountains Abbey pub across the road. But having a dirty lab alone doesn\u2019t, unfortunately, guarantee you Nobel Prizes \u2013 if it did, I could easily rank my PhD students in order of likelihood of winning one. Fleming\u2019s brilliance lay in seeing the breakthrough in an otherwise unplanned situation.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:120,&quot;335559740&quot;:276}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">The fungi contaminating Fleming\u2019s plates was a <\/span><i><span data-contrast=\"auto\">Penicillium<\/span><\/i><span data-contrast=\"auto\">, from which he named the active compound penicillin. Nothing much happened between the initial discovery in 1928 and 1940, when Howard Florey and Ernst Chain (latterly of Imperial), while working at Oxford University, developed a process for extracting penicillin from fungal broth, for which they shared the 1945 Nobel Prize with Fleming. Antibiotics have dramatically changed the face of modern medicine. Many bacterial infections that were once fatal can now be managed.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:120,&quot;335559740&quot;:276}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">However, there is a looming shadow on the horizon. We are seeing a huge rise in antibiotic resistance, which is not as it might sound: it does not mean resistance of people to antibiotics, but the ability of certain bacteria to survive antibiotic treatment. Drug resistance (sometimes called antimicrobial resistance or \u2018AMR\u2019) is a serious problem: each year half a million people die around the world because of resistant bacteria. The problem isn\u2019t necessarily a new one, Fleming predicted the emergence of antibiotic resistance in 1945. But it is gathering pace. Not just for bacterial infections, but also for fungal ones too.\u00a0<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:120,&quot;335559740&quot;:276}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">But there is room for optimism. A new hope is rising phoenix-like (or emerging penicillium-like, to keep the microbial analogy) at St Mary\u2019s. <\/span><a href=\"https:\/\/www.fleminginitiative.org\/\"><span data-contrast=\"none\">The Fleming Initiative<\/span><\/a><span data-contrast=\"auto\">, established jointly by Imperial College London and Imperial College Healthcare NHS Trust, is bringing together researchers, policymakers, clinicians, behavioural experts, commercial partners and the public to find solutions to antimicrobial resistance at a global scale. \u00a0It has already gained the support of the UK government, including founding partner GSK. \u00a0It will drive the creation of the Fleming Centre, a new research and public engagement facility to be built on the canal-side next to St Mary\u2019s, just metres away from Fleming\u2019s original discovery. <\/span><span data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;201341983&quot;:0,&quot;335551550&quot;:1,&quot;335551620&quot;:1,&quot;335559685&quot;:0,&quot;335559737&quot;:0,&quot;335559738&quot;:0,&quot;335559739&quot;:120,&quot;335559740&quot;:276}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">As Sir Alexander showed, innovation can come from the most unlikely of sources, we hope to carry on his legacy.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Professor John Tregoning, Professor of Vaccine Immunology in the Department of Infectious Disease, explores the legacy of Sir Alexander Fleming and the urgent fight against antimicrobial resistance. From the historic discovery of penicillin at St Mary\u2019s Medical School to the ambitious Fleming Initiative, Professor Tregoning discusses how a groundbreaking new centre aims to tackle one [&hellip;]<\/p>\n","protected":false},"author":1080,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[296217],"tags":[296246,272422,294,248146,200866,211,81],"class_list":["post-5033","post","type-post","status-publish","format-standard","hentry","category-department-of-infectious-disease","tag-clinical-research","tag-disease-awareness","tag-global-health","tag-infectious-disease","tag-medical-school","tag-public-health","tag-research"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Fleming\u2019s Final Flourish - Imperial Medicine Blog<\/title>\n<meta name=\"description\" content=\"Professor John Tregoning explores the legacy of Sir Alexander Fleming and the urgent fight against antimicrobial resistance. From the historic discovery of penicillin at St Mary\u2019s Medical School to the ambitious Fleming Initiative, he discusses how this groundbreaking new centre aims to tackle one of the greatest challenges in modern medicine.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/blogs.imperial.ac.uk\/imperial-medicine\/2025\/01\/01\/flemings-final-flourish\/\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Fleming\u2019s Final Flourish - Imperial Medicine Blog\" \/>\n<meta property=\"og:description\" content=\"Professor John Tregoning explores the legacy of Sir Alexander Fleming and the urgent fight against antimicrobial resistance. From the historic discovery of penicillin at St Mary\u2019s Medical School to the ambitious Fleming Initiative, he discusses how this groundbreaking new centre aims to tackle one of the greatest challenges in modern medicine.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/blogs.imperial.ac.uk\/imperial-medicine\/2025\/01\/01\/flemings-final-flourish\/\" \/>\n<meta property=\"og:site_name\" content=\"Imperial Medicine Blog\" \/>\n<meta property=\"article:published_time\" content=\"2025-01-01T07:00:48+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/blogs.imperial.ac.uk\/imperial-medicine\/files\/2024\/12\/St-Marys-Campus.png\" \/>\n\t<meta property=\"og:image:width\" content=\"1181\" \/>\n\t<meta property=\"og:image:height\" content=\"660\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"John Tregoning\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"John Tregoning\" \/>\n\t<meta name=\"twitter:label2\" content=\"Estimated reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/blogs.imperial.ac.uk\/imperial-medicine\/2025\/01\/01\/flemings-final-flourish\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/blogs.imperial.ac.uk\/imperial-medicine\/2025\/01\/01\/flemings-final-flourish\/\"},\"author\":{\"name\":\"John Tregoning\",\"@id\":\"https:\/\/blogs.imperial.ac.uk\/imperial-medicine\/#\/schema\/person\/13495a63a5732b02bab62a786598e500\"},\"headline\":\"Fleming\u2019s Final Flourish\",\"datePublished\":\"2025-01-01T07:00:48+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/blogs.imperial.ac.uk\/imperial-medicine\/2025\/01\/01\/flemings-final-flourish\/\"},\"wordCount\":622,\"image\":{\"@id\":\"https:\/\/blogs.imperial.ac.uk\/imperial-medicine\/2025\/01\/01\/flemings-final-flourish\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/blogs.imperial.ac.uk\/imperial-medicine\/files\/2024\/12\/St-Marys-Campus.png\",\"keywords\":[\"Clinical research\",\"Disease awareness\",\"Global health\",\"Infectious disease\",\"Medical school\",\"Public health\",\"Research\"],\"articleSection\":[\"Department of Infectious Disease\"],\"inLanguage\":\"en-GB\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/blogs.imperial.ac.uk\/imperial-medicine\/2025\/01\/01\/flemings-final-flourish\/\",\"url\":\"https:\/\/blogs.imperial.ac.uk\/imperial-medicine\/2025\/01\/01\/flemings-final-flourish\/\",\"name\":\"Fleming\u2019s Final Flourish - Imperial Medicine Blog\",\"isPartOf\":{\"@id\":\"https:\/\/blogs.imperial.ac.uk\/imperial-medicine\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/blogs.imperial.ac.uk\/imperial-medicine\/2025\/01\/01\/flemings-final-flourish\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/blogs.imperial.ac.uk\/imperial-medicine\/2025\/01\/01\/flemings-final-flourish\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/blogs.imperial.ac.uk\/imperial-medicine\/files\/2024\/12\/St-Marys-Campus.png\",\"datePublished\":\"2025-01-01T07:00:48+00:00\",\"author\":{\"@id\":\"https:\/\/blogs.imperial.ac.uk\/imperial-medicine\/#\/schema\/person\/13495a63a5732b02bab62a786598e500\"},\"description\":\"Professor John Tregoning explores the legacy of Sir Alexander Fleming and the urgent fight against antimicrobial resistance. From the historic discovery of penicillin at St Mary\u2019s Medical School to the ambitious Fleming Initiative, he discusses how this groundbreaking new centre aims to tackle one of the greatest challenges in modern medicine.\",\"inLanguage\":\"en-GB\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/blogs.imperial.ac.uk\/imperial-medicine\/2025\/01\/01\/flemings-final-flourish\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-GB\",\"@id\":\"https:\/\/blogs.imperial.ac.uk\/imperial-medicine\/2025\/01\/01\/flemings-final-flourish\/#primaryimage\",\"url\":\"https:\/\/blogs.imperial.ac.uk\/imperial-medicine\/files\/2024\/12\/St-Marys-Campus.png\",\"contentUrl\":\"https:\/\/blogs.imperial.ac.uk\/imperial-medicine\/files\/2024\/12\/St-Marys-Campus.png\",\"width\":1181,\"height\":660},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/blogs.imperial.ac.uk\/imperial-medicine\/#website\",\"url\":\"https:\/\/blogs.imperial.ac.uk\/imperial-medicine\/\",\"name\":\"Imperial Medicine Blog\",\"description\":\"Stories from Imperial&#039;s Faculty of Medicine\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/blogs.imperial.ac.uk\/imperial-medicine\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-GB\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/blogs.imperial.ac.uk\/imperial-medicine\/#\/schema\/person\/13495a63a5732b02bab62a786598e500\",\"name\":\"John Tregoning\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-GB\",\"@id\":\"https:\/\/secure.gravatar.com\/avatar\/1f62426cd38cc95643d703b8e4bf87cd2eb94b0007fc24f882e5d9c8ec4cec35?s=96&d=mm&r=g\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/1f62426cd38cc95643d703b8e4bf87cd2eb94b0007fc24f882e5d9c8ec4cec35?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/1f62426cd38cc95643d703b8e4bf87cd2eb94b0007fc24f882e5d9c8ec4cec35?s=96&d=mm&r=g\",\"caption\":\"John Tregoning\"},\"url\":\"https:\/\/blogs.imperial.ac.uk\/imperial-medicine\/author\/jst99\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Fleming\u2019s Final Flourish - Imperial Medicine Blog","description":"Professor John Tregoning explores the legacy of Sir Alexander Fleming and the urgent fight against antimicrobial resistance. From the historic discovery of penicillin at St Mary\u2019s Medical School to the ambitious Fleming Initiative, he discusses how this groundbreaking new centre aims to tackle one of the greatest challenges in modern medicine.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/blogs.imperial.ac.uk\/imperial-medicine\/2025\/01\/01\/flemings-final-flourish\/","og_locale":"en_GB","og_type":"article","og_title":"Fleming\u2019s Final Flourish - Imperial Medicine Blog","og_description":"Professor John Tregoning explores the legacy of Sir Alexander Fleming and the urgent fight against antimicrobial resistance. From the historic discovery of penicillin at St Mary\u2019s Medical School to the ambitious Fleming Initiative, he discusses how this groundbreaking new centre aims to tackle one of the greatest challenges in modern medicine.","og_url":"https:\/\/blogs.imperial.ac.uk\/imperial-medicine\/2025\/01\/01\/flemings-final-flourish\/","og_site_name":"Imperial Medicine Blog","article_published_time":"2025-01-01T07:00:48+00:00","og_image":[{"width":1181,"height":660,"url":"https:\/\/blogs.imperial.ac.uk\/imperial-medicine\/files\/2024\/12\/St-Marys-Campus.png","type":"image\/png"}],"author":"John Tregoning","twitter_card":"summary_large_image","twitter_misc":{"Written by":"John Tregoning","Estimated reading time":"3 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/blogs.imperial.ac.uk\/imperial-medicine\/2025\/01\/01\/flemings-final-flourish\/#article","isPartOf":{"@id":"https:\/\/blogs.imperial.ac.uk\/imperial-medicine\/2025\/01\/01\/flemings-final-flourish\/"},"author":{"name":"John Tregoning","@id":"https:\/\/blogs.imperial.ac.uk\/imperial-medicine\/#\/schema\/person\/13495a63a5732b02bab62a786598e500"},"headline":"Fleming\u2019s Final Flourish","datePublished":"2025-01-01T07:00:48+00:00","mainEntityOfPage":{"@id":"https:\/\/blogs.imperial.ac.uk\/imperial-medicine\/2025\/01\/01\/flemings-final-flourish\/"},"wordCount":622,"image":{"@id":"https:\/\/blogs.imperial.ac.uk\/imperial-medicine\/2025\/01\/01\/flemings-final-flourish\/#primaryimage"},"thumbnailUrl":"https:\/\/blogs.imperial.ac.uk\/imperial-medicine\/files\/2024\/12\/St-Marys-Campus.png","keywords":["Clinical research","Disease awareness","Global health","Infectious disease","Medical school","Public health","Research"],"articleSection":["Department of Infectious Disease"],"inLanguage":"en-GB"},{"@type":"WebPage","@id":"https:\/\/blogs.imperial.ac.uk\/imperial-medicine\/2025\/01\/01\/flemings-final-flourish\/","url":"https:\/\/blogs.imperial.ac.uk\/imperial-medicine\/2025\/01\/01\/flemings-final-flourish\/","name":"Fleming\u2019s Final Flourish - Imperial Medicine Blog","isPartOf":{"@id":"https:\/\/blogs.imperial.ac.uk\/imperial-medicine\/#website"},"primaryImageOfPage":{"@id":"https:\/\/blogs.imperial.ac.uk\/imperial-medicine\/2025\/01\/01\/flemings-final-flourish\/#primaryimage"},"image":{"@id":"https:\/\/blogs.imperial.ac.uk\/imperial-medicine\/2025\/01\/01\/flemings-final-flourish\/#primaryimage"},"thumbnailUrl":"https:\/\/blogs.imperial.ac.uk\/imperial-medicine\/files\/2024\/12\/St-Marys-Campus.png","datePublished":"2025-01-01T07:00:48+00:00","author":{"@id":"https:\/\/blogs.imperial.ac.uk\/imperial-medicine\/#\/schema\/person\/13495a63a5732b02bab62a786598e500"},"description":"Professor John Tregoning explores the legacy of Sir Alexander Fleming and the urgent fight against antimicrobial resistance. From the historic discovery of penicillin at St Mary\u2019s Medical School to the ambitious Fleming Initiative, he discusses how this groundbreaking new centre aims to tackle one of the greatest challenges in modern medicine.","inLanguage":"en-GB","potentialAction":[{"@type":"ReadAction","target":["https:\/\/blogs.imperial.ac.uk\/imperial-medicine\/2025\/01\/01\/flemings-final-flourish\/"]}]},{"@type":"ImageObject","inLanguage":"en-GB","@id":"https:\/\/blogs.imperial.ac.uk\/imperial-medicine\/2025\/01\/01\/flemings-final-flourish\/#primaryimage","url":"https:\/\/blogs.imperial.ac.uk\/imperial-medicine\/files\/2024\/12\/St-Marys-Campus.png","contentUrl":"https:\/\/blogs.imperial.ac.uk\/imperial-medicine\/files\/2024\/12\/St-Marys-Campus.png","width":1181,"height":660},{"@type":"WebSite","@id":"https:\/\/blogs.imperial.ac.uk\/imperial-medicine\/#website","url":"https:\/\/blogs.imperial.ac.uk\/imperial-medicine\/","name":"Imperial Medicine Blog","description":"Stories from Imperial&#039;s Faculty of Medicine","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/blogs.imperial.ac.uk\/imperial-medicine\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-GB"},{"@type":"Person","@id":"https:\/\/blogs.imperial.ac.uk\/imperial-medicine\/#\/schema\/person\/13495a63a5732b02bab62a786598e500","name":"John Tregoning","image":{"@type":"ImageObject","inLanguage":"en-GB","@id":"https:\/\/secure.gravatar.com\/avatar\/1f62426cd38cc95643d703b8e4bf87cd2eb94b0007fc24f882e5d9c8ec4cec35?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/1f62426cd38cc95643d703b8e4bf87cd2eb94b0007fc24f882e5d9c8ec4cec35?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/1f62426cd38cc95643d703b8e4bf87cd2eb94b0007fc24f882e5d9c8ec4cec35?s=96&d=mm&r=g","caption":"John Tregoning"},"url":"https:\/\/blogs.imperial.ac.uk\/imperial-medicine\/author\/jst99\/"}]}},"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/pg9uH0-1jb","jetpack_likes_enabled":false,"_links":{"self":[{"href":"https:\/\/blogs.imperial.ac.uk\/imperial-medicine\/wp-json\/wp\/v2\/posts\/5033","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.imperial.ac.uk\/imperial-medicine\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.imperial.ac.uk\/imperial-medicine\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.imperial.ac.uk\/imperial-medicine\/wp-json\/wp\/v2\/users\/1080"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.imperial.ac.uk\/imperial-medicine\/wp-json\/wp\/v2\/comments?post=5033"}],"version-history":[{"count":4,"href":"https:\/\/blogs.imperial.ac.uk\/imperial-medicine\/wp-json\/wp\/v2\/posts\/5033\/revisions"}],"predecessor-version":[{"id":5040,"href":"https:\/\/blogs.imperial.ac.uk\/imperial-medicine\/wp-json\/wp\/v2\/posts\/5033\/revisions\/5040"}],"wp:attachment":[{"href":"https:\/\/blogs.imperial.ac.uk\/imperial-medicine\/wp-json\/wp\/v2\/media?parent=5033"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.imperial.ac.uk\/imperial-medicine\/wp-json\/wp\/v2\/categories?post=5033"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.imperial.ac.uk\/imperial-medicine\/wp-json\/wp\/v2\/tags?post=5033"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}