Latest publications: September-October 2020

Imperial Campus (lion statue)

Congratulations to members of the Department who have recently had their research findings published. Here’s our round-up of recent publication successes.*

Title Date Authors OR Authors/Contributors Type Canonical journal title
In-hospital mortality is associated with inflammatory response in NAFLD patients admitted for COVID-19 01/10/2020 Forlano R, Mullish B, Mukherjee S, Nathwani R, Harlow C, Crook P, Judge R, Soubieres A, Middleton P, Daunt A, Perez Guzman P, Selvapatt N, Lemoine M, Dhar A, Thursz MR, Nayagam S, Manousou P Journal article Hepatology
A Pilot Study of Gut-Brain Signaling After Octreotide Therapy for Unintentional Weight Loss After Esophagectomy. 30/09/2020 Murphy CF, Stratford N, Docherty NG, Moran B, Elliott JA, Healy M-L, McMorrow JP, Ravi N, Goldstone AP, Reynolds JV, le Roux CW Journal Article Journal of Clinical Endocrinology and Metabolism
A randomised, controlled pilot study of cognitive analytic therapy (CAT) for stressed pregnant women with underlying anxiety and depression in a routine health service setting. 30/09/2020 Hamilton J, Saxon D, Best E, Glover V, Walters SJ, Kerr IB Journal Article Clinical Psychology and Psychotherapy: an international journal of theory and practice
A Standardized Strategy for Simultaneous Quantification of Urine Metabolites to Validate Development of a Biomarker Panel Allowing Comprehensive Assessment of Dietary Exposure 28/09/2020 Beckmann M, Wilson T, Zubair H, Lloyd AJ, Lyons L, Phillips H, Tailliart K, Gregory N, Thatcher R, Garcia-Perez I, Frost G, Mathers JM, Draper J Article, Early Access, Journal Molecular Nutrition and Food Research
Aberrant subcutaneous adipogenesis precedes adult metabolic dysfunction in an ovine model of polycystic ovary syndrome (PCOS). 01/10/2020 Siemienowicz KJ, Coukan F, Franks S, Rae MT, Duncan WC Journal Article Molecular and Cellular Endocrinology
Adaptations to the British Society of Gastroenterology guidelines on the management of acute severe UC in the context of the COVID-19 pandemic: a RAND appropriateness panel 01/10/2020 Din S, Kent A, Pollok RC, Meade S, Kennedy NA, Arnott I, Beattie RM, Chua F, Cooney R, Dart RJ, Galloway J, Gaya DR, Ghosh S, Griffiths M, Hancock L, Hansen R, Hart A, Lamb CA, Lees CW, Limdi JK, Lindsay JO, Patel K, Powell N, Murray CD, Probert C, Raine T, Selinger C, Sebastian S, Smith PJ, Tozer P, Ustianowski A, Younge L, Samaan MA, Irving PM Article, Journal Gut
Adipocyte-specific deletion of Tcf7l2 induces dysregulated lipid metabolism and impairs glucose tolerance in mice. 17/10/2020 Nguyen-Tu M-S, Martinez-Sanchez A, Leclerc I, Rutter GA, da Silva Xavier G Journal Article Diabetologia
Altered Cardiovascular Defense to Hypotensive Stress in the Chronically Hypoxic Fetus 01/10/2020 Allison BJ, Brain KL, Niu Y, Kane AD, Herrera EA, Thakor AS, Botting KJ, Cross CM, Itani N, Shaw CJ, Skeffington KL, Beck C, Giussani DA Article, Journal Hypertension
Androgenic Anabolic Steroid induced liver injury: 2 cases reports assessed for causality by the updated Roussel Uclaf Causality Assessment Method (RUCAM) score and a comprehensive review of the literature. 03/10/2020 Abeles R, Foxton M, Khan S, Goldin R, Smith B, Thursz M, Verma S Journal article BMJ Open Gastroenterology
Assessment of Glucose Control Metrics by Discriminant Ratio. 01/10/2020 Moscardó V, Herrero P, Reddy M, Hill NR, Georgiou P, Oliver N Journal Article Diabetes Technology and Therapeutics
Assessment of protein biomarkers for preoperative differential diagnosis between benign and malignant ovarian tumors. 26/09/2020 Landolfo C, Achten ETL, Ceusters J, Baert T, Froyman W, Heremans R, Vanderstichele A, Thirion G, Van Hoylandt A, Claes S, Oosterlynck J, Van Rompuy AS, Schols D, Billen J, Van Calster B, Bourne T, Van Gorp T, Vergote I, Timmerman D, Coosemans A Journal Article Gynecologic Oncology
Association between hyperemesis gravidarum and psychological symptoms, psychosocial outcomes and infant bonding: a two-point prospective case-control multicentre survey study in an inner city setting. 13/10/2020 Mitchell-Jones N, Lawson K, Bobdiwala S, Farren JA, Tobias A, Bourne T, Bottomley C Journal Article BMJ Open
Associations of type 1 and type 2 diabetes with COVID-19-related mortality in England: a whole-population study 01/10/2020 Barron E, Bakhai C, Kar P, Weaver A, Bradley D, Ismail H, Knighton P, Holman N, Khunti K, Sattar N, Wareham NJ, Young B, Valabhji J Review, Journal The Lancet Diabetes and Endocrinology
Author Correction: Metabolism of the predominant human milk oligosaccharide fucosyllactose by an infant gut commensal. 09/10/2020 James K, Bottacini F, Contreras JIS, Vigoureux M, Egan M, Motherway MO, Holmes E, van Sinderen D Published Erratum Scientific Reports
Author Correction: MiR-31 promotes mammary stem cell expansion and breast tumorigenesis by suppressing Wnt signaling antagonists. 15/10/2020 Lv C, Li F, Li X, Tian Y, Zhang Y, Sheng X, Song Y, Meng Q, Yuan S, Luan L, Andl T, Feng X, Jiao B, Xu M, Plikus MV, Dai X, Lengner C, Cui W, Ren F, Shuai J, Millar SE, Yu Z Published Erratum Nature Communications
Author Correction: Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics. 09/10/2020 Ast J, Arvaniti A, Fine NHF, Nasteska D, Ashford FB, Stamataki Z, Koszegi Z, Bacon A, Jones BJ, Lucey MA, Sasaki S, Brierley DI, Hastoy B, Tomas A, D’Agostino G, Reimann F, Lynn FC, Reissaus CA, Linnemann AK, D’Este E, Calebiro D, Trapp S, Johnsson K, Podewin T, Broichhagen J, Hodson DJ Published Erratum Nature Communications
Baclofen: To screen or not to screen in postmortem blood? 27/09/2020 Nahar LK, Murphy KG, Paterson S Article Journal of Analytical Toxicology
Breast cancer–associated macrophages promote tumorigenesis by suppressing succinate dehydrogenase in tumor cells 06/10/2020 Gómez V, Eykyn TR, Mustapha R, Flores-Borja F, Male V, Barber PR, Patsialou A, Green R, Panagaki F, Li CW, Fruhwirth GO, Ros S, Brindle KM, Ng T Article Science Signaling
Cervical cancer prevention in transgender men: a review 02/10/2020 Weyers S, Garland SM, Cruickshank M, Kyrgiou M, Arbyn M Review, Early Access, Journal BJOG: an International Journal of Obstetrics and Gynaecology
Chikungunya virus strains from each genetic clade bind sulfated glycosaminoglycans as attachment factors. 30/09/2020 McAllister N, Liu Y, Silva LM, Lentscher AJ, Chai W, Wu N, Griswold KA, Raghunathan K, Vang L, Alexander J, Warfield KL, Diamond MS, Feizi T, Silva LA, Dermody TS Journal Article Journal of Virology
Consequences of Lipid Remodeling of Adipocyte Membranes Being Functionally Distinct from Lipid Storage in Obesity. 02/10/2020 Liu K-D, Acharjee A, Hinz C, Liggi S, Murgia A, Denes J, Gulston MK, Wang X, Chu Y, West JA, Glen RC, Roberts LD, Murray AJ, Griffin JL Journal Article Journal of Proteome Research
Cortisol concentrations and mortality from COVID-19 reply 01/10/2020 Tan T, Khoo B, Mills EG, Phylactou M, Patel B, Eng PC, Thurston L, Muzi B, Meeran K, Prevost AT, Comninos AN, Abbara A, Dhillo WS Letter, Journal The Lancet Diabetes and Endocrinology
Differential effects of L- and D-phenylalanine on pancreatic and gastrointestinal hormone release in humans: a randomised crossover study. 29/09/2020 Amin A, Frampton J, Liu Z, Franco-Becker G, Norton M, Alaa A, Li JV, Murphy KG Journal Article Diabetes, Obesity and Metabolism: a journal of pharmacology and therapeutics
Dissemination and analysis of the quality assurance (QA) and quality control (QC) practices of LC-MS based untargeted metabolomics practitioners. 12/10/2020 Evans AM, O’Donovan C, Playdon M, Beecher C, Beger RD, Bowden JA, Broadhurst D, Clish CB, Dasari S, Dunn WB, Griffin JL, Hartung T, Hsu P-C, Huan T, Jans J, Jones CM, Kachman M, Kleensang A, Lewis MR, Monge ME, Mosley JD, Taylor E, Tayyari F, Theodoridis G, Torta F, Ubhi BK, Vuckovic D, Metabolomics Quality Assurance, Quality Control Consortium (mQACC) Journal Article Metabolomics
Effect of COVID-19 lockdown on alcohol consumption in patients with pre-existing alcohol use disorder 01/10/2020 Kim JU, Majid A, Judge R, Crook P, Nathwani R, Selvapatt N, Lovendoski J, Manousou P, Thursz M, Dhar A, Lewis H, Vergis N, Lemoine M Letter, Journal The Lancet Gastroenterology and Hepatology
Endocrine requirements for oocyte maturation following hCG, GnRH agonist and kisspeptin during IVF treatment 06/10/2020 Abbara A, Hunjan T, NGOC ANH Ho V, Clarke S, Comninos A, Izzi-Engbeaya C, ho T, Trew G, hramyka A, kelsey T, salim R, humaidan P, vuong L, Dhillo W Article Frontiers in Endocrinology
Evolving type 1 diabetes in distinguishing between type 1 and type 2 diabetes. 29/09/2020 Hill NE, Oliver NS Letter BMJ: British Medical Journal
First-trimester fetal neurosonography: technique and diagnostic potential. 13/10/2020 Volpe N, Dall’Asta A, Di Pasquo E, Frusca T, Ghi T Journal Article, Review Ultrasound in Obstetrics and Gynecology
Global hepatitis C elimination: an investment framework 01/10/2020 Pedrana A, Howell J, Scott N, Schroeder S, Kuschel C, Lazarus J, Atun R, Baptista-Leite R, t’Hoen E, Hutchinson SJ, Aufegger L, Peck R, Sohn AH, Swan T, Thursz M, Lesi O, Sharma M, Thwaites J, Wilson DP, Hellard M Article, Journal The Lancet Gastroenterology and Hepatology
Glucose management for exercise using continuous glucose monitoring (CGM) and intermittently scanned CGM (isCGM) systems in type 1 diabetes: position statement of the European Association for the Study of Diabetes (EASD) and of the International Society for Pediatric and Adolescent Diabetes (ISPAD) endorsed by JDRF and supported by the American Diabetes Association (ADA). 13/10/2020 Moser O, Riddell MC, Eckstein ML, Adolfsson P, Rabasa-Lhoret R, van den Boom L, Gillard P, Nørgaard K, Oliver NS, Zaharieva DP, Battelino T, de Beaufort C, Bergenstal RM, Buckingham B, Cengiz E, Deeb A, Heise T, Heller S, Kowalski AJ, Leelarathna L, Mathieu C, Stettler C, Tauschmann M, Thabit H, Wilmot EG, Sourij H, Smart CE, Jacobs PG, Bracken RM, Mader JK Editorial Diabetologia
GUIDELINES AND GOOD CLINICAL PRACTICE RECOMMENDATIONS FOR CONTRAST-ENHANCED ULTRASOUND (CEUS) IN THE LIVER-UPDATE 2020 WFUMB IN COOPERATION WITH EFSUMB, AFSUMB, AIUM, AND FLAUS 01/10/2020 Dietrich CF, Nolsoe CP, Barr RG, Berzigotti A, Burns PN, Cantisani V, Chammas MC, Chaubal N, Choi BI, Clevert D-A, Cui X, Dong Y, D’Onofrio M, Fowlkes JB, Gilja OH, Huang P, Ignee A, Jenssen C, Kono Y, Kudo M, Lassau N, Lee WJ, Lee JY, Liang P, Lim A, Lyshchik A, Meloni MF, Correas JM, Minami Y, Moriyasu F, Nicolau C, Piscaglia F, Saftoiu A, Sidhu PS, Sporea I, Torzilli G, Xie X, Zheng R Review, Journal Ultrasound in Medicine and Biology
Hepatitis B virus preS2Δ38-55 variants: A newly identified risk factor for hepatocellular carcinoma. 01/10/2020 Cohen D, Ghosh S, Shimakawa Y, Ramou N, Garcia PS, Dubois A, Guillot C, Kakwata-Nkor Deluce N, Tilloy V, Durand G, Voegele C, Ndow G, d’Alessandro U, Brochier-Armanet C, Alain S, Le Calvez-Kelm F, Hall J, Zoulim F, Mendy M, Thursz M, Lemoine M, Chemin I Journal Article JHEP Reports
Imperial Satiety Protocol: A new non-surgical weight-loss programme, delivered in a health care setting, produces improved clinical outcomes for people with obesity. 29/09/2020 Hameed S, Salem V, Alessimii H, Scholtz S, Dar O, Miras AD, Meeran K, Bloom SR, Ahmed AR, Purkayastha S, Chahal H, Tan T Journal Article Diabetes, Obesity and Metabolism: a journal of pharmacology and therapeutics
In Severe Alcoholic Hepatitis, Serum Keratin-18 Fragments Are Diagnostic, Prognostic, and Theragnostic Biomarkers. 01/10/2020 Atkinson SR, Grove JI, Liebig S, Astbury S, Vergis N, Goldin R, Quaglia A, Bantel H, Guha IN, Thursz MR, Newcombe P, Strnad P, Aithal GP Journal Article American Journal of Gastroenterology
Increased MicroRNA levels in women with polycystic ovarian syndrome but without insulin resistance: a pilot prospective study 30/09/2020 Butler A, Ramachandran V, Cunningham T, David R, Gooderham N, Benurwar M, Dargham S, Hayat S, Sathypalan T, Najafi-Shoushtari H, Atkin S Article Frontiers in Endocrinology
Inflammatory Bowel Disease Outcomes Following Fecal Microbiota Transplantation for Recurrent C. difficile Infection 02/10/2020 Allegretti JR, Kelly CR, Grinspan A, Mullish BH, Hurtado J, Carrellas M, Marcus J, Marchesi JR, McDonald JAK, Gerardin Y, Silverstein M, Pechlivanis A, Barker GF, Miguens Blanco J, Alexander JL, Gallagher KI, Pettee W, Phelps E, Nemes S, Sagi SV, Bohm M, Kassam Z, Fischer M Journal article Inflammatory Bowel Diseases
In-hospital mortality is associated with inflammatory response in NAFLD patients admitted for COVID-19. 12/07/1905 Forlano R, Mullish BH, Mukherjee SK, Nathwani R, Harlow C, Crook P, Judge R, Soubieres A, Middleton P, Daunt A, Perez-Guzman P, Selvapatt N, Lemoine M, Dhar A, Thursz MR, Nayagam S, Manousou P Journal Article PLoS One
Interesting case of dual pathology: Crohn’s disease and Peutz-Jeghers syndrome. 04/10/2020 Sehmbhi M, Sellers P, Segal J, Clark S Journal Article BMJ Case Reports
Intrapartum fetal heart rate between 150 and 160 bpm at or after 40 weeks and labor outcome. 13/10/2020 Ghi T, Di Pasquo E, Dall’asta A, Commare A, Melandri E, Casciaro A, Fieni S, Frusca T Journal Article Acta Obstetricia et Gynecologica Scandinavica
Laser-assisted rapid evaporative ionisation mass spectrometry (LA-REIMS) as a metabolomics platform in cervical cancer screening. 24/09/2020 Paraskevaidi M, Cameron SJS, Whelan E, Bowden S, Tzafetas M, Mitra A, Semertzidou A, Athanasiou A, Bennett PR, MacIntyre DA, Takats Z, Kyrgiou M Journal Article EBioMedicine
Metabolic and functional specialisations of the pancreatic beta cell: gene disallowance, mitochondrial metabolism and intercellular connectivity 01/10/2020 Rutter GA, Georgiadou E, Martinez-Sanchez A, Pullen TJ Review, Journal Diabetologia
No-fault compensation for cerebral palsy associated with pregnancy care in Japan. 02/10/2020 Ushiro S, Steer PJ Journal Article BJOG: an International Journal of Obstetrics and Gynaecology
Non-invasive splenic parameters of portal hypertension: Assessment and utility 09/10/2020 Lim A, Ahmad A, Atzori S, Maurice J, Taylor-Robinson S Journal article World Journal of Hepatology
Optimal extent of initial parathyroid resection in patients with multiple endocrine neoplasia syndrome type 1: A meta-analysis. 29/09/2020 Nastos C, Papaconstantinou D, Kofopoulos-Lymperis E, Peppa M, Pikoulis A, Lykoudis P, Palazzo F, Patapis P, Pikoulis E Journal Article, Review Surgery
Pharmacological programming of endosomal signaling activated by small molecule ligands of the follicle stimulating hormone receptor 19/10/2020 Sposini S, De Pascali F, Richardson R, Sayers S, Perrais D, Yu H, Palmer S, Nataraja S, Reiter E, Hanyaloglu A Journal article Frontiers in Pharmacology
Prenatal mental health and the effects of stress on the foetus and the child. Should psychiatrists look beyond mental disorders? 01/10/2020 Glover V Editorial Material, Editorial, Journal World Psychiatry
Quantitative In-Vitro Diagnostic NMR Spectroscopy for Lipoprotein and Metabolite Measurements in Plasma and Serum: Recommendations for Analytical Artifact Minimization with Special Reference to COVID-19/SARS-CoV-2 Samples. 16/10/2020 Loo RL, Lodge S, Kimhofer T, Bong S-H, Begum S, Whiley L, Gray N, Lindon JC, Nitschke P, Lawler NG, Schäfer H, Spraul M, Richards T, Nicholson JK, Holmes E Journal Article Journal of Proteome Research
Quantitative In-Vitro Diagnostic NMR Spectroscopy for Lipoprotein and Metabolite Measurements in Plasma and Serum: Recommendations for Analytical Artifact Minimization with Special Reference to COVID-19/SARS-CoV-2 Samples. 16/10/2020 Loo RL, Lodge S, Kimhofer T, Bong S-H, Begum S, Whiley L, Gray N, Lindon JC, Nitschke P, Lawler NG, Schäfer H, Spraul M, Richards T, Nicholson JK, Holmes E Journal Article Journal of Proteome Research
Quantitative In-Vitro Diagnostic NMR Spectroscopy for Lipoprotein and Metabolite Measurements in Plasma and Serum: Recommendations for Analytical Artifact Minimization with Special Reference to COVID-19/SARS-CoV-2 Samples. 16/10/2020 Loo RL, Lodge S, Kimhofer T, Bong S-H, Begum S, Whiley L, Gray N, Lindon JC, Nitschke P, Lawler NG, Schäfer H, Spraul M, Richards T, Nicholson JK, Holmes E Journal Article Journal of Proteome Research
Reply to Woodworth, et al. 14/10/2020 Mullish BH, Ghani R, McDonald JAK, Davies F, Marchesi JR Journal Article Clinical Infectious Diseases
Response to Comment on Misra et al. Homozygous Hypomorphic HNF1A Alleles Are a Novel Cause of Young-Onset Diabetes and Result in Sulfonylurea-Sensitive Diabetes. Diabetes Care 2020;43:909-912 01/10/2020 Misra S, Hassanali N, Bennett AJ, Juszczak A, Caswell R, Colclough K, Valabhji J, Ellard S, Oliver NS, Gloyn AL Letter, Journal Diabetes Care
Risk factors for COVID-19-related mortality in people with type 1 and type 2 diabetes in England: a population-based cohort study 01/10/2020 Holman N, Knighton P, Kar P, O’Keefe J, Curley M, Weaver A, Barron E, Bakhai C, Khunti K, Wareham NJ, Sattar N, Young B, Valabhji J Article, Journal The Lancet Diabetes and Endocrinology
Safety and feasibility of the PEPPER adaptive bolus advisor and safety system; a randomized control study. 13/10/2020 Avari P, Leal Y, Herrero P, Wos M, Jugnee N, Arnoriaga-Rodríguez M, Thomas M, Liu C, Massana Q, Lopez B, Nita L, Martin C, Fernandez-Real JM, Oliver N, Fernandez M, Reddy M Journal Article Diabetes Technology and Therapeutics
Short chain fatty acids enhance expression and activity of the umami taste receptor in enteroendocrine cells via a Galphai/o pathway 29/09/2020 Shackley M, Ma Y, Brown A, Tate E, Frost G, Hanyaloglu A Journal article Frontiers in Nutrition
STROBE-metagenomics: a STROBE extension statement to guide the reporting of metagenomics studies. 01/10/2020 Bharucha T, Oeser C, Balloux F, Brown JR, Carbo EC, Charlett A, Chiu CY, Claas ECJ, de Goffau MC, de Vries JJC, Eloit M, Hopkins S, Huggett JF, MacCannell D, Morfopoulou S, Nath A, O’Sullivan DM, Reoma LB, Shaw LP, Sidorov I, Simner PJ, Van Tan L, Thomson EC, van Dorp L, Wilson MR, Breuer J, Field N Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov’t, Review Lancet Infectious Diseases
The type 2 diabetes gene product STARD10 is a phosphoinositide-binding protein that controls insulin secretory granule biogenesis 01/10/2020 Carrat GR, Haythorne E, Tomas A, Haataja L, Mueller A, Arvan P, Piunti A, Cheng K, Huang M, Pullen TJ, Georgiadou E, Stylianides T, Amirruddin NS, Salem V, Distaso W, Cakebread A, Heesom KJ, Lewis PA, Hodson DJ, Briant LJ, Fung ACH, Sessions RB, Alpy F, Kong APS, Benke P, Torta F, Teo AKK, Leclerc I, Solimena M, Wigley DB, Rutter GA Article, Journal Molecular Metabolism
Transcutaneous fluorescence spectroscopy as a tool for non-invasive monitoring of gut function: first clinical experiences. 30/09/2020 Maurice J, Lett AM, Skinner C, Lim A, Richardson M, Thomas AP, Summers PA, Vyas K, Tadbier AW, Vilar R, Kuimova MK, Miodragovic S, Vergis N, Kelly P, Cordeiro MF, Hoare J, Darzi A, Goldin R, Thursz M, Thompson AJ Journal Article Scientific Reports
Using Aptamers as a Novel Method for Determining GnRH/LH Pulsatility. 07/10/2020 Izzi-Engbeaya C, Abbara A, Cass A, Dhillo WS Journal Article, Review International Journal of Molecular Sciences
Validity of the UK early access to medicines scheme criteria for Remdesivir use in patients with COVID-19 disease 01/10/2020 Daunt A, Perez-Guzman PN, Liew F, Hauck K, Costelloe CE, Thursz MR, Cooke G, Nayagam S Letter, Journal Journal of Infection
What is the impact of food reformulation on individual’s behaviour, nutrient intakes and health status? A systematic review of empirical evidence 06/10/2020 Gressier M, Swinburn B, Frost G, Segal AB, Sassi F Review, Early Access, Journal Obesity Reviews


*The mysterious case of the missing publication: a disclaimer

To ensure the quality and accuracy of the information published on this blog, we source our data directly from Symplectic. Our reports are generated on a fortnightly basis, which means there may be a delay in publicising some publications. 

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