{"id":108,"date":"2022-05-15T08:57:07","date_gmt":"2022-05-15T08:57:07","guid":{"rendered":"https:\/\/blogs.imperial.ac.uk\/my-path\/?p=108"},"modified":"2022-05-15T15:20:42","modified_gmt":"2022-05-15T15:20:42","slug":"tertiary-syphilis","status":"publish","type":"post","link":"https:\/\/blogs.imperial.ac.uk\/my-path\/2022\/05\/15\/tertiary-syphilis\/","title":{"rendered":"Syphilitic Aortic Aneurysm"},"content":{"rendered":"<p><strong>Tertiary syphilis:<\/strong><br \/>\n1.\tcardiovascular syphilis,<br \/>\n2.\tneurosyphilis (meningovascular syphilis, tabes dorsalis and general paralysis of the insane ).<br \/>\n3.\t\u201cbenign \u201ctertiary syphilis.<br \/>\nAfter 5 years in 1\/3rd of untreated patient<\/p>\n<p><strong>Cardiovascular syphilis<\/strong><br \/>\n80% of cases of  tertiary syphilis<br \/>\nProbably immune mediated<br \/>\nEndarteritis of the vaso vasorum leading to fibrosis of the media<br \/>\nIncreasing dilatation of the  aortic root (leading to aortic incompetence) and arch (leading to an aneurysm).<br \/>\nAlso, obstruction of the coronary artery ostia leading to ischaemia<\/p>\n<p><strong>Other causes of aortitis:<\/strong><br \/>\n1.\tGiant cell arteritis (&gt;50).<br \/>\n2.\tTakayasu\u2019s arteritis  (&lt;50).<br \/>\nBoth may involve the eye.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"156\" src=\"https:\/\/blogs.imperial.ac.uk\/my-path\/files\/2022\/05\/Picture-1-300x156.jpg\" alt=\"\" class=\"alignnone size-medium wp-image-109\" \/><\/p>\n<p>https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMicm2110835<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"230\" src=\"https:\/\/blogs.imperial.ac.uk\/my-path\/files\/2022\/05\/FSzTKmoWUAIBt90-300x230.jpeg\" alt=\"\" class=\"alignnone size-medium wp-image-114\" \/><\/p>\n<p>Avraham Z. Cooper, MD @AvrahamCooperMD<br \/>\n&#8220;Pulsatile chest swelling &#x27a1;&#xfe0f; HUGE aortic aneurysm from tertiary syphilis.&#8221;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Tertiary syphilis: 1. cardiovascular syphilis, 2. neurosyphilis (meningovascular syphilis, tabes dorsalis and general paralysis of the insane ). 3. \u201cbenign \u201ctertiary syphilis. After 5 years in 1\/3rd of untreated patient Cardiovascular syphilis 80% of cases of tertiary syphilis Probably immune mediated Endarteritis of the vaso vasorum leading to fibrosis of the media Increasing dilatation of [&hellip;]<\/p>\n","protected":false},"author":1119,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[290089,318391,247574],"tags":[],"class_list":["post-108","post","type-post","status-publish","format-standard","hentry","category-cardiac-pathology","category-nejm","category-year-5"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Syphilitic Aortic Aneurysm - My Path<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/blogs.imperial.ac.uk\/my-path\/2022\/05\/15\/tertiary-syphilis\/\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Syphilitic Aortic Aneurysm - My Path\" \/>\n<meta property=\"og:description\" content=\"Tertiary syphilis: 1. cardiovascular syphilis, 2. neurosyphilis (meningovascular syphilis, tabes dorsalis and general paralysis of the insane ). 3. \u201cbenign \u201ctertiary syphilis. 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