Latest publications: February 2023

Congratulations to members of the Department who have recently had their research findings published. Here’s our round-up of the latest publication successes.

To ensure the quality and accuracy of the information published on this blog, we source our data directly from Symplectic. Our reports are generated on a monthly basis, which means there may be a delay in publicising some publications.

Title Canonical journal title Publication type Authors OR Authors/Contributors Publication date
2022 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations: Summary From the Basic Life Support; Advanced Life Support; Pediatric Life Support; Neonatal Life Support; Education, Implementation, and Teams; and First Aid Task Forces. Pediatrics Journal Article Wyckoff MH, Greif R, Morley PT, Ng K-C, Olasveengen TM, Singletary EM, Soar J, Cheng A, Drennan IR, Liley HG, Scholefield BR, Smyth MA, Welsford M, Zideman DA, Maconochie IK et al. 01/02/2023
A systematic review of risk factors for mortality among tuberculosis patients in South Africa. Systematic Reviews Journal Article, Review, Systematic Review Nicholson TJ, Hoddinott G, Seddon JA, Claassens MM, van der Zalm MM, Lopez E, Bock P, Caldwell J, Da Costa D, de Vaal C, Dunbar R, Du Preez K, Hesseling AC, Joseph K, Kriel E, Loveday M, Marx FM, Meehan S-A, Purchase S, Naidoo K, Naidoo L, Solomon-Da Costa F, Sloot R, Osman M 23/02/2023
Actinobacillus pleuropneumoniae encodes multiple phase-variable DNA methyltransferases that control distinct phasevarions Nucleic Acids Research Article, Early Access, Journal Nahar N, Tram G, Jen FE-C, Phillips ZN, Weinert LA, Bosse JT, Jabbari JS, Gouil Q, Du MRM, Ritchie ME, Bowden R, Langford PR, Tucker AW, Jennings MP, Turni C, Blackall PJ, Atack JM 25/02/2023
Adoption of C-reactive protein point-of-care tests for the management of acute childhood infections in primary care in the Netherlands and England: a comparative health systems analysis. BMC Health Services Research Review, Journal Article Dewez JE, Nijman RG, Fitchett EJA, Lynch R, de Groot R, van der Flier M, Philipsen R, Vreugdenhil H, Ettelt S, Yeung S 23/02/2023
AI writing tools could hand scientists the ‘gift of time’. Nature Journal Article Tregoning J 22/02/2023
Atypical lymphocytes-From chickenpox to monkey pox American Journal of Hematology Editorial Material, Early Access, Editorial material, Journal Nesr G, Whittaker E, Bain BJ 27/02/2023
CAR-iNKT cells targeting clonal TCRVβ chains as a precise strategy to treat T cell lymphoma Frontiers in Immunology Journal Article Rowan A, Ponnusamy K, Ren H, Taylor G, Cook L, Karadimitris A 02/03/2023
Cerebrospinal fluid virology in people with HIV. HIV Medicine Journal Article Henderson M, Pepper N, Bawa M, Muir D, Everitt A, Mackie NE, Winston A 09/03/2023
Characteristics and predictors of persistent symptoms post-COVID-19 in children and young people: a large community cross-sectional study in England. Archives of Disease in Childhood Journal Article Atchison CJ, Whitaker M, Donnelly CA, Chadeau-Hyam M, Riley S, Darzi A, Ashby D, Barclay W, Cooke GS, Elliott P, Ward H 02/03/2023
Cohort-Specific Peptide Reagents Broaden Depth and Breadth Estimates of the CD8 T Cell Response to HIV-1 Gag Potential T Cell Epitopes. Vaccines Journal Article Michelo CM, Fiore-Gartland A, Dalel JA, Hayes P, Tang J, McGowan E, Kilembe W, Fernandez N, Gilmour J, Hunter E 17/02/2023
Comparison of the frequency and phenotypic profile of Mycobacterium tuberculosis-specific CD4 T cells between the site of disease and blood in pericardial tuberculosis (vol 13, 1009016, 2022) Frontiers in Immunology Correction, Journal Du Bruyn E, Ruzive S, Howlett P, Cerrone M, Jacobs AJ, Arlehamn CLS, Sette A, Sher A, Mayer-Barber KD, Barber DL, Mayosi B, Ntsekhe M, Wilkinson RJ, Riou C 06/02/2023
Computational decision-support tools for urban design to improve resilience against COVID-19 and other infectious diseases: A systematic review Progress in Planning Review, Journal Yang L, Iwami M, Chen Y, Wu M, van Dam KH 02/02/2023
Correction to: Febrile illness in high-risk children: a prospective, international observational study. European Journal of Pediatrics Published Erratum van der Velden FJS, de Vries G, Martin A, Lim E, von Both U, Kolberg L, Carrol ED, Khanijau A, Herberg JA, De T, Galassini R, Kuijpers TW, Martinón-Torres F, Rivero-Calle I, Vermont CL, Hagedoorn NN, Pokorn M, Pollard AJ, Schlapbach LJ, Tsolia M, Elefhteriou I, Yeung S, Zavadska D, Fink C, Voice M, Zenz W, Kohlmaier B, Agyeman PKA, Usuf E, Secka F, de Groot R, Levin M, van der Flier M, Emonts M, PERFORM consortium 01/02/2023
Correction to: Group A streptococcal disease in paediatric inpatients: a European perspective. European Journal of Pediatrics Published Erratum Boeddha NP, Atkins L, de Groot R, Driessen G, Hazelzet J, Zenz W, Carrol ED, Anderson ST, Martinon-Torres F, Agyeman PKA, Galassini R, Herberg J, Levin M, Schlapbach LJ, Emonts M, EUCLIDS consortium 01/02/2023
COVAC1 phase 2a expanded safety and immunogenicity study of a self-amplifying RNA vaccine against SARS-CoV-2. EClinicalMedicine Journal Article Szubert AJ, Pollock KM, Cheeseman HM, Alagaratnam J, Bern H, Bird O, Boffito M, Byrne R, Cole T, Cosgrove CA, Faust SN, Fidler S, Galiza E, Hassanin H, Kalyan M, Libri V, McFarlane LR, Milinkovic A, O’Hara J, Owen DR, Owens D, Pacurar M, Rampling T, Skene S, Winston A, Woolley J, Yim YTN, Dunn DT, McCormack S, Shattock RJ, COVAC 1 Study Team 01/02/2023
COVID-19: Brief overview of therapeutic strategies. Anaesthesia, Critical Care and Pain Medicine Letter, Review Beaumont A-L, Rozencwajg S, Peiffer-Smadja N, Montravers P 01/02/2023
Decision criteria for selecting essential medicines and their connection to guidelines: an interpretive descriptive qualitative interview study. Journal of Clinical Epidemiology Journal Article Piggott T, Moja L, Akl EA, Lavis JN, Cooke G, Kredo T, Hogerzeil HV, Huttner B, Alonso-Coello P, Schünemann H 01/02/2023
Detection of Novel Actinobacillus pleuropneumoniae Serovars by Multiplex PCR: a Cautionary Tale Microbiology Spectrum Letter, Early Access, Journal Li Y, Bosse JT, Stringer OW, Hennig-Pauka I, Mortensen P, Langford PR 01/02/2023
Diabetes mellitus is not a predictor of poor TB treatment outcomes. International Journal of Tuberculosis and Lung Disease Observational Study, Journal Article Baltas I, Sturdy A, Kavallieros K, McGregor A, Corrah T, John L, Cooke G, Whittington AM 01/02/2023
Disruption to water supply and waterborne communicable diseases in northeast Syria: a spatiotemporal analysis Conflict and Health Article, Journal Tabor R, Almhawish N, Aladhan I, Tarnas M, Sullivan R, Karah N, Zeitoun M, Ratnayake R, Abbara A 04/02/2023
European study confirms the combination of fever and petechial rash as an important warning sign for childhood sepsis and meningitis. Acta Paediatrica: promoting child health Journal Article Kohlmaier B, Leitner M, Hagedoorn NN, Borensztajn DM, von Both U, Carrol ED, Emonts M, van der Flier M, de Groot R, Herberg J, Levin M, Lim E, Maconochie IK, Martinon-Torres F, Nijman RG, Pokorn M, Rivero-Calle I, Tan CD, Maria T, Vermont CL, Zachariasse JM, Zavadska D, Moll HA, Zenz W, PERFORM consortium (Personalised Risk assessment in febrile children to optimise Real-life Management across the European Union) 03/03/2023
Growth Arrest of Staphylococcus aureus Induces Daptomycin Tolerance via Cell Wall Remodelling mBio Article, Early Access, Journal Ledger EVK, Edwards AM 01/02/2023
Heart rate and respiratory rate in predicting risk of serious bacterial infection in febrile children given antipyretics: prospective observational study. European Journal of Pediatrics Journal Article Wittmann S, Jorgensen R, Oostenbrink R, Moll H, Herberg J, Levin M, Maconochie I, Nijman R 03/03/2023
Identification and characterization of thousands of bacteriophage satellites across bacteria. Nucleic Acids Research Journal Article de Sousa JAM, Fillol-Salom A, Penadés JR, Rocha EPC 03/03/2023
Identification and control for the effects of bioinformatic globin depletion on human RNA-seq differential expression analysis. Scientific Reports Journal Article Sheerin D, Lakay F, Esmail H, Kinnear C, Sansom B, Glanzmann B, Wilkinson RJ, Ritchie ME, Coussens AK 01/02/2023
IL-27 inhibits anti- Mycobacterium tuberculosis innate immune activity of primary human macrophages. Tuberculosis Journal Article Gollnick H, Barber J, Wilkinson RJ, Newton S, Garg A 24/02/2023
Immunoglobulin, glucocorticoid, or combination therapy for multisystem inflammatory syndrome in children: a propensity-weighted cohort study. The Lancet Rheumatology Journal Article Channon-Wells S, Vito O, McArdle AJ, Seaby EG, Patel H, Shah P, Pazukhina E, Wilson C, Broderick C, D’Souza G, Keren I, Nijman RG, Tremoulet A, Munblit D, Ulloa-Gutierrez R, Carter MJ, Ramnarayan P, De T, Hoggart C, Whittaker E, Herberg JA, Kaforou M, Cunnington AJ, Blyuss O, Levin M, Best Available Treatment Study (BATS) consortium 14/02/2023
Implementing antibiotic stewardship in high-prescribing English general practices: a mixed-methods study British Journal of General Practice Article, Early Access, Journal Tonkin-Crine S, McLeod M, Borek AJ, Campbell A, Anyanwu P, Costelloe C, Moore M, Hayhoe B, Pouwels KB, Roope LSJ, Morrell L, Hopkins S, Butler CC, Walker AS 20/02/2023
Infliximab and Tofacitinib Attenuate Neutralizing Antibody Responses Against SARS-CoV-2 Ancestral and Omicron Variants in Inflammatory Bowel Disease Patients After 3 Doses of COVID-19 Vaccine. Gastroenterology Letter, Research Support, Non-U.S. Gov’t Liu Z, Alexander JL, Lin KW, VIP Study Investigators, Ahmad T, Pollock KM, Powell N 01/02/2023
Intranasal immunisation with Outer Membrane Vesicles (OMV) protects against airway colonisation and systemic infection with Acinetobacter baumannii. Journal of Infection Journal Article Higham SL, Baker S, Flight KE, Krishna A, Kellam P, Reece ST, Tregoning JS 27/02/2023
Learning meaningful latent space representations for patient risk stratification: Model development and validation for dengue and other acute febrile illness. Frontiers in Digital Health Journal Article Hernandez B, Stiff O, Ming DK, Ho Quang C, Nguyen Lam V, Nguyen Minh T, Nguyen Van Vinh C, Nguyen Minh N, Nguyen Quang H, Phung Khanh L, Dong Thi Hoai T, Dinh The T, Huynh Trung T, Wills B, Simmons CP, Holmes AH, Yacoub S, Georgiou P, Vietnam ICU Translational Applications Laboratory (VITAL) investigators 15/07/1905
Mapping patient pathways and understanding clinical decision-making in dengue management to inform the development of digital health tools BMC Medical Informatics and Decision Making Journal Article Nguyen QH, Ming DK, Luu AP, Chanh HQ, Tam DTH, Truong NT, Huy VX, Hernandez B, Van Nuil JI, Paton C, Georgiou P, Nguyen NM, Holmes A, Tho PV, Yacoub S 02/02/2023
Mpox infection investigation using multiplexed syndromic diagnostics: Evaluation of an AusDiagnostics multiplexed tandem PCR (MT-PCR) syndromic panel Article, Journal Pona MJ, Al-Mufti J, Madona P, Crone MA, Lain KG, Hale RS, Muir D, Randell P 03/02/2023
Neutralising antibody potency against SARS-CoV-2 wild-type and omicron BA.1 and BA.4/5 variants in patients with inflammatory bowel disease treated with infliximab and vedolizumab after three doses of COVID-19 vaccine (CLARITY IBD): an analysis of a prospective multicentre cohort study. The Lancet Gastroenterology & Hepatology Observational Study, Multicenter Study, Journal Article, Research Support, Non-U.S. Gov’t Liu Z, Le K, Zhou X, Alexander JL, Lin S, Bewshea C, Chanchlani N, Nice R, McDonald TJ, Lamb CA, Sebastian S, Kok K, Lees CW, Hart AL, Pollok RC, Boyton RJ, Altmann DM, Pollock KM, Goodhand JR, Kennedy NA, Ahmad T, Powell N, CLARITY study investigators 01/02/2023
Next-generation molecular diagnostics: Leveraging digital technologies to enhance multiplexing in real-time PCR Trends in Analytical Chemistry Journal Article Kreitmann L, Miglietta L, Xu K, Malpartida-Cardenas K, D’Souza G, Kaforou M, Brengel-Pesce K, Drazek L, Holmes A, Rodriguez-Manzano J 01/03/2023
PPNet: Identifying functional association networks by phylogenetic profiling of prokaryotic genomes Microbiology Spectrum Journal Article Li Y, Ma B, Hua K, Gong H, He R, Luo R, Bi D, Zhou R, Langford PR, Jin H 01/02/2023
Proteomic Analysis of Mucosal and Systemic Responses to SARS-CoV-2 Antigen. Vaccines Journal Article Martinson N, Gordhan B, Petkov S, Pillay A-D, Seiphetlo T, Singh N, Otwombe K, Lebina L, Fredolini C, Chiodi F, Fox J, Kana B, Herrera C 02/02/2023
PRSet: Pathway-based polygenic risk score analyses and software. PLoS Genetics Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov’t Choi SW, García-González J, Ruan Y, Wu HM, Porras C, Johnson J, Bipolar Disorder Working group of the Psychiatric Genomics Consortium, Hoggart CJ, O’Reilly PF 01/02/2023
QuantiFERON-TB Gold Plus Performance in Children: A Narrative Review. The Pediatric Infectious Disease Journal Journal Article Buonsenso D, Seddon JA, Esposito S, Barcellini L 15/02/2023
Ready, STAT3, Go! Bacteria in the race for M2 macrophage polarisation. Current Opinion in Microbiology Journal Article, Review Panagi I, Thurston TL 27/02/2023
Recurrent visceral leishmaniasis relapses in HIV co-infected patients are characterized by less efficient immune responses and higher parasite load. iScience Journal Article Takele Y, Mulaw T, Adem E, Womersley R, Kaforou M, Franssen SU, Levin M, Taylor GP, Müller I, Cotton JA, Kropf P 17/02/2023
Respective roles of non-pharmaceutical interventions in bronchiolitis outbreaks: an interrupted time-series analysis based on a multinational surveillance system. European Respiratory Journal Journal Article Lenglart L, Ouldali N, Honeyford K, Bognar Z, Bressan S, Buonsenso D, Da Dalt L, De T, Farrugia R, Maconochie IK, Moll HA, Oostenbrink R, Parri N, Roland D, Rose K, Akyüz Özkan E, Angoulvant F, Aupiais C, Barber C, Barrett M, Basmaci R, Castanhinha S, Chiaretti A, Durnin S, Fitzpatrick P, Fodor L, Gomez B, Greber-Platzer S, Guedj R, Hey F, Jankauskaite L, Kohlfuerst D, Mascarenhas I, Musolino AM, Pučuka Z, Reis S, Rybak A, Salamon P, Schaffert M, Shahar-Nissan K, Supino MC, Teksam O, Turan C, Velasco R, Nijman RG, Titomanlio L, EPISODES Study Group 01/02/2023
Respiratory viruses: New frontiers-a Keystone Symposia report. Annals of the New York Academy of Sciences Journal Article Cable J, Sun J, Cheon IS, Vaughan AE, Castro IA, Stein SR, López CB, Gostic KM, Openshaw PJM, Ellebedy AH, Wack A, Hutchinson E, Thomas MM, Langlois RA, Lingwood D, Baker SF, Folkins M, Foxman EF, Ward AB, Schwemmle M, Russell AB, Chiu C, Ganti K, Subbarao K, Sheahan TP, Penaloza-MacMaster P, Eddens T 01/02/2023
SARS-CoV-2 surface and air contamination in an acute healthcare setting during the first and second pandemic waves Journal of Hospital Infection Article, Journal Otter JA, Zhou J, Price JR, Reeves L, Zhu N, Randell P, Sriskandan S, Barclay WS, Holmes AH 01/02/2023
Slow progression of pediatric HIV associates with early CD8+ T cell PD-1 expression and a stem-like phenotype. JCI Insight Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov’t Vieira V, Lim N, Singh A, Leitman E, Dsouza R, Adland E, Muenchhoff M, Roider J, Marin Lopez M, Carabelli J, Giandhari J, Groll A, Jooste P, Prado JG, Thobakgale C, Dong K, Kiepiela P, Prendergast AJ, Tudor-Williams G, Frater J, Walker BD, Ndung’u T, Ramsuran V, Leslie A, Kløverpris HN, Goulder P 08/02/2023
The Drug-Induced Interface That Drives HIV-1 Integrase Hypermultimerization and Loss of Function. mBio Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov’t Singer MR, Dinh T, Levintov L, Annamalai AS, Rey JS, Briganti L, Cook NJ, Pye VE, Taylor IA, Kim K, Engelman AN, Kim B, Perilla JR, Kvaratskhelia M, Cherepanov P 28/02/2023
The effect of interleukin-6 signaling on severe malaria: A Mendelian randomization analysis. International Journal of Infectious Diseases Journal Article Hamilton F, Mitchell RE, Constantinescu A, Hughes D, Cunnington A, Ghazal P, Timpson NJ 16/02/2023
The epidemiology and burden of neuromyelitis optica spectrum disorder, multiple sclerosis, and MOG antibody-associated disease in a province in Thailand: A population-based study. Multiple Sclerosis and Related Disorders Journal Article Tisavipat N, Jitpratoom P, Siritho S, Prayoonwiwat N, Apiwattanakul M, Boonyasiri A, Rattanathamsakul N, Jitprapaikulsan J 01/02/2023
The role of CD8+ T cell clones in immune thrombocytopenia. Blood Journal Article Malik A, Sayed AA, Han P, Tan MMH, Watt E, Constantinescu-Bercu A, Cocker ATH, Khoder A, Saputil RC, Thorley EV, Teklemichael A, Ding Y, Hart ACJ, Zhang H, Mitchell WA, Imami N, Crawley JTB, Salles-Crawley II, Bussel JB, Zehnder JL, Adams SP, Zhang BM, Cooper N 07/02/2023
The use of representative community samples to assess SARS-CoV-2 lineage competition: Alpha outcompetes Beta and wild-type in England from January to March 2021. Microbial Genomics Journal Article Eales O, Page AJ, Tang SN, Walters CE, Wang H, Haw D, Trotter AJ, Le Viet T, Foster-Nyarko E, Prosolek S, Atchison C, Ashby D, Cooke G, Barclay W, Donnelly CA, O’Grady J, Volz E, The Covid-Genomics Uk Cog-Uk Consortium, Darzi A, Ward H, Elliott P, Riley S 01/02/2023
Three-year trends in out-of-hospital cardiac arrest across the world: second report from the International Liaison Committee on Resuscitation (ILCOR). Resuscitation Journal Article Nishiyama C, Kiguchi T, Okubo M, Alihodžić H, Al-Araji R, Baldi E, Beganton F, Booth S, Bray J, Christensen E, Cresta R, Finn J, Grasner J-T, Jouven X, Kern KB, Maconochie I, Masterson S, McNally B, Nolan JP, Eng Hock Ong M, Perkins GD, Ho Park J, Ristau P, Savastano S, Shahidah N, Do Shin S, Soar J, Tjelmeland I, Quinn MO, Wnent J, Wyckoff MH, Iwami T, ILCOR Research and Registries Working Group 01/03/2023
Use of cidofovir in a patient with severe mpox and uncontrolled HIV infection. Lancet Infectious Diseases Journal Article, Review Stafford A, Rimmer S, Gilchrist M, Sun K, Davies EP, Waddington CS, Chiu C, Armstrong-James D, Swaine T, Davies F, Gómez CHM, Kumar V, ElHaddad A, Awad Z, Smart C, Mora-Peris B, Muir D, Randell P, Peters J, Chand M, Warrell CE, Rampling T, Cooke G, Dhanji S, Campbell V, Davies C, Osman S, Abbara A 08/02/2023
Use of contraindicated antiretroviral drugs in people with HIV/HCV coinfections receiving HCV treatment with direct-acting antivirals-Results from the EuroSIDA study. HIV Medicine Journal Article Nikolaichuk M, Mocroft A, Wandeler G, Szlavik J, Gottfredsson M, Reikvam DH, Svedhem V, Elinav H, Laguno M, Mansinho K, Devitt E, Chkhartishvili N, Behrens G, Bogner J, Viard J-P, Winston A, Benfield T, Leen C, Fursa O, Rockstroh J, Peters L, EuroSIDA study group 01/02/2023
XerC is required for the repair of antibiotic- and immune-mediated DNA damage in staphylococcus aureus Antimicrobial Agents and Chemotherapy Journal Article Ledger E, Lau K, Tate E, Edwards A 21/02/2023

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