Latest publications: January 2024

Congratulations to members of the Department who have recently had their research findings published. Here’s our round-up of the latest publication successes.

To ensure the quality and accuracy of the information published on this blog, we source our data directly from Symplectic. Our reports are generated on a monthly basis, which means there may be a delay in publicising some publications.


Title Canonical journal title Publication type Authors OR Author/Contributors Publication date
“Getting pregnant during COVID-19 was a big risk because getting help from the clinic was not easy”: COVID-19 experiences of women and healthcare providers in Harare, Zimbabwe. PLOS Global Public Health Journal Article Mupambireyi Z, Cowan FM, Chappell E, Chimwaza A, Manika N, Wedderburn CJ, Gannon H, Gibb T, Heys M, Fitzgerald F, Chimhuya S, Gibb D, Ford D, Mushavi A, Bwakura-Dangarembizi M 08/01/2024
A CRISPR-Cas12a-based platform facilitates the detection and serotyping of Streptococcus suis serotype 2 Talanta Article, Journal Wang L, Sun J, Zhao J, Bai J, Zhang Y, Zhu Y, Zhang W, Wang C, Langford PR, Liu S, Li G 15/01/2024
A low-volume LC/MS method for highly sensitive monitoring of phenoxymethylpenicillin, benzylpenicillin, and probenecid in human serum. Analytical Methods: advancing methods and applications Journal Article Riezk A, Wilson RC, Cass AEG, Holmes AH, Rawson TM 25/01/2024
A novel computational pipeline for var gene expression augments the discovery of changes in the Plasmodium falciparum transcriptome during transition from in vivo to short-term in vitro culture. eLife Journal Article Andradi-Brown C, Wichers-Misterek JS, von Thien H, Höppner YD, Scholz JAM, Hansson H, Filtenborg Hocke E, Gilberger TW, Duffy MF, Lavstsen T, Baum J, Otto TD, Cunnington AJ, Bachmann A 25/01/2024
An assessment of the airborne longevity of group A Streptococcus. Microbiology Journal Article Oswin HP, Blake E, Haddrell AE, Finn A, Sriskandan S, Reid JP, Halliday A, Goenka A 01/01/2024
Antagonistic interactions between phage and host factors control arbitrium lysis-lysogeny decision. Nature Microbiology Journal Article Zamora-Caballero S, Chmielowska C, Quiles-Puchalt N, Brady A, Del Sol FG, Mancheño-Bonillo J, Felipe-Ruíz A, Meijer WJJ, Penadés JR, Marina A 01/01/2024
BACH1 promotes tissue necrosis and Mycobacterium tuberculosis susceptibility. Nature Microbiology Journal Article Amaral EP, Namasivayam S, Queiroz ATL, Fukutani E, Hilligan KL, Aberman K, Fisher L, Bomfim CCB, Kauffman K, Buchanan J, Santuo L, Gazzinelli-Guimaraes PH, Costa DL, Teixeira MA, Barreto-Duarte B, Rocha CG, Santana MF, Cordeiro-Santos M, Barber DL, Wilkinson RJ, Kramnik I, Igarashi K, Scriba T, Mayer-Barber KD, Andrade BB, Sher A 01/01/2024
BridgePRS leverages shared genetic effects across ancestries to increase polygenic risk score portability. Nature Genetics Journal Article Hoggart CJ, Choi SW, García-González J, Souaiaia T, Preuss M, O’Reilly PF 01/01/2024
Cortactin stabilizes actin branches by bridging activated Arp2/3 to its nucleated actin filament. Nature Structural and Molecular Biology Journal Article Liu T, Cao L, Mladenov M, Jegou A, Way M, Moores CA 24/01/2024
Development and Implementation of Digital Diagnostic Algorithms for Neonatal Units in Zimbabwe and Malawi: Development and Usability Study. JMIR Formative Research Journal Article Gannon H, Larsson L, Chimhuya S, Mangiza M, Wilson E, Kesler E, Chimhini G, Fitzgerald F, Zailani G, Crehan C, Khan N, Hull-Bailey T, Sassoon Y, Baradza M, Heys M, Chiume M 26/01/2024
Development and Validation of the Phoenix Criteria for Pediatric Sepsis and Septic Shock. JAMA: Journal of the American Medical Association Journal Article Sanchez-Pinto LN, Bennett TD, DeWitt PE, Russell S, Rebull MN, Martin B, Akech S, Albers DJ, Alpern ER, Balamuth F, Bembea M, Chisti MJ, Evans I, Horvat CM, Jaramillo-Bustamante JC, Kissoon N, Menon K, Scott HF, Weiss SL, Wiens MO, Zimmerman JJ, Argent AC, Sorce LR, Schlapbach LJ, Watson RS, Society of Critical Care Medicine Pediatric Sepsis Definition Task Force, Biban P, Carrol E, Chiotos K, Flauzino De Oliveira C, Hall MW, Inwald D, Ishimine P, Levin M, Lodha R, Nadel S, Nakagawa S, Peters MJ, Randolph AG, Ranjit S, Souza DC, Tissieres P, Wynn JL 21/01/2024
Digital remote monitoring for screening and early detection of urinary tract infections. npj Digital Medicine Journal Article Capstick A, Palermo F, Zakka K, Fletcher-Lloyd N, Walsh C, Cui T, Kouchaki S, Jackson R, Tran M, Crone M, Jensen K, Freemont P, Vaidyanathan R, Kolanko M, True J, Daniels S, Wingfield D, CR&T Group, Nilforooshan R, Barnaghi P 13/01/2024
Distinguishing community-acquired bacterial and viral meningitis: Microbes and biomarkers. Journal of Infection Journal Article, Review Ivaska L, Herberg J, Sadarangani M 01/02/2024
DLL4/Notch3/WNT5B axis mediates bidirectional prometastatic crosstalk between melanoma and lymphatic endothelial cells. JCI Insight Journal Article Alve S, Gramolelli S, Jukonen J, Juteau S, Pink A, Manninen AA, Hänninen S, Monto E, Lackman MH, Carpén O, Saharinen P, Karaman S, Vaahtomeri K, Ojala PM 09/01/2024
Effects of the COVID-19 pandemic on the outcomes of HIV-exposed neonates: a Zimbabwean tertiary hospital experience. BMC Pediatrics Journal Article, Research Support Gannon H, Chappell E, Ford D, Gibb DM, Chimwaza A, Manika N, Wedderburn CJ, Nenguke ZM, Cowan FM, Gibb T, Phillips A, Mushavi A, Fitzgerald F, Heys M, Chimhuya S, Bwakura-Dangarembizi M 05/01/2024
Enhanced active case finding of drug-resistant tuberculosis in Namibia: a protocol for the hotspots, hospitals, and households (H3TB) study BMJ Open Journal Article Shavuka O, Lipumbu E, Boois L, Gunther G, Hoddinott G, Lin H, Nepolo E, Niemann S, Ruswa N, Seddon J, Claassens M 10/02/2024
Evolution of enhanced innate immune suppression by SARS-CoV-2 Omicron subvariants. Nature Microbiology Journal Article Reuschl A-K, Thorne LG, Whelan MVX, Ragazzini R, Furnon W, Cowton VM, De Lorenzo G, Mesner D, Turner JLE, Dowgier G, Bogoda N, Bonfanti P, Palmarini M, Patel AH, Jolly C, Towers GJ 16/01/2024
Factors associated with an increased risk of developing pneumonia during acute ischemic stroke hospitalization. PLoS One Observational Study, Journal Article Jitpratoom P, Boonyasiri A 10/01/2024
Fifteen-minute consultation: Managing post-COVID-19 syndrome (long COVID) in children and young people Archives of Disease in Childhood: Education and Practice Edition Article, Early Access, Journal Wacks M, Wortley E, Gregorowski A, Segal TY, Whittaker E 23/01/2024
Hepatic steatosis in people older and younger than fifty who are living with HIV and HIV-negative controls: A cross-sectional study nested within the POPPY cohort HIV Medicine Article, Early Access, Journal Arenas-Pinto A, Bakewell N, Milinkovic A, Williams I, Vera J, Post FA, Anderson J, Beynon M, O’Brien A, Doyle N, Gilson R, Pett SL, Winston A, Sabin CA 01/01/2024
Histidine transport is essential for the growth of Staphylococcus aureus at low pH PLoS Pathogens Article Beetham CM, Schuster CF, Kviatkovski I, Santiago M, Walker S, Gründling A 16/01/2024
How do socioeconomic determinants of health affect the likelihood of living with HTLV-1 globally? A systematic review with meta-analysis Frontiers in Public Health Journal Article Ramesh N, Cockbain B, Taylor GP, Rosadas de Oliveira C 01/01/2024
How does the microbiota control systemic innate immunity? Trends in Immunology Journal Article, Review Jordan CKI, Clarke TB 11/01/2024
HTLV-1 induces an inflammatory CD4+CD8+ T cell population in HTLV-1-associated myelopathy. JCI Insight Journal Article Maher AK, Aristodemou A, Giang N, Tanaka Y, Bangham CR, Taylor GP, Dominguez-Villar M 09/01/2024
Hypertension care cascades and reducing inequities in cardiovascular disease in low- and middle-income countries. Nature Medicine Journal Article Stein DT, Reitsma MB, Geldsetzer P, Agoudavi K, Aryal KK, Bahendeka S, Brant LCC, Farzadfar F, Gurung MS, Guwatudde D, Houehanou YCN, Malta DC, Martins JS, Saeedi Moghaddam S, Mwangi KJ, Norov B, Sturua L, Zhumadilov Z, Bärnighausen T, Davies JI, Flood D, Marcus ME, Theilmann M, Vollmer S, Manne-Goehler J, Atun R, Sudharsanan N, Verguet S 26/01/2024
Identification and management of co-infections in those with malaria BMJ: British Medical Journal Journal Article Cunnington A, Abbara A, Kaduni Bawa F, Achan J 13/03/2024
Immune responses and clinical outcomes after COVID-19 vaccination in patients with liver disease and liver transplant recipients. Journal of Hepatology Journal Article Murray SM, Pose E, Wittner M, Londoño M-C, Schaub G, Cook J, Dimitriadis S, Meacham G, Irwin S, Lim Z, Duengelhoef P, Sterneck M, Lohse AW, Perez V, Trivedi P, Bhandal K, Mullish BH, Manousou P, Provine NM, Avitabile E, Carroll M, Tipton T, Healy S, Burra P, Klenerman P, Dunachie S, Kronsteiner B, Maciola AK, Pasqual G, Hernandez-Gea V, Garcia-Pagan JC, Lampertico P, Iavarone M, Gines P, Lütgehetmann M, Schulze Zur Wiesch J, Russo FP, Barnes E, Marjot T, OCTAVE Collaborative Group, PITCH study, and the EASL supported COVID-Hep vaccine network 01/01/2024
Impact of pregnancy vaccine uptake and socio-demographic determinants on subsequent childhood Measles, Mumps and Rubella vaccine uptake: A UK birth cohort study. Vaccine Journal Article Skirrow H, Foley K, Bedford H, Lewis C, Whittaker E, Costelloe C, Saxena S 12/01/2024
Impaired lung function in adolescents with pulmonary tuberculosis during treatment and following treatment completion. EClinicalMedicine Journal Article van der Zalm MM, Jongen VW, Swanepoel R, Zimri K, Allwood B, Palmer M, Dunbar R, Goussard P, Schaaf HS, Hesseling AC, Seddon JA 01/01/2024
Integrated analysis of patient networks and plasmid genomes reveals a regional, multi-species outbreak of carbapenemase-producing Enterobacterales carrying both blaIMP and mcr-9 genes. Journal of Infectious Diseases Journal Article Wan Y, Myall AC, Boonyasiri A, Bolt F, Ledda A, Mookerjee S, Weiße AY, Getino M, Turton JF, Abbas H, Prakapaite R, Sabnis A, Abdolrasouli A, Malpartida-Cardenas K, Miglietta L, Donaldson H, Gilchrist M, Hopkins KL, Ellington MJ, Otter JA, Larrouy-Maumus G, Edwards AM, Rodriguez-Manzano J, Didelot X, Barahona M, Holmes AH, Jauneikaite E, Davies F 20/01/2024
International Consensus Criteria for Pediatric Sepsis and Septic Shock. JAMA: Journal of the American Medical Association Journal Article Schlapbach LJ, Watson RS, Sorce LR, Argent AC, Menon K, Hall MW, Akech S, Albers DJ, Alpern ER, Balamuth F, Bembea M, Biban P, Carrol ED, Chiotos K, Chisti MJ, DeWitt PE, Evans I, Flauzino de Oliveira C, Horvat CM, Inwald D, Ishimine P, Jaramillo-Bustamante JC, Levin M, Lodha R, Martin B, Nadel S, Nakagawa S, Peters MJ, Randolph AG, Ranjit S, Rebull MN, Russell S, Scott HF, de Souza DC, Tissieres P, Weiss SL, Wiens MO, Wynn JL, Kissoon N, Zimmerman JJ, Sanchez-Pinto LN, Bennett TD, Society of Critical Care Medicine Pediatric Sepsis Definition Task Force 21/01/2024
Mentorship as an overlooked dimension of research capacity strengthening: how to embed value-driven practices in global health. BMJ Global Health Journal Article Bonaconsa C, Nampoothiri V, Mbamalu O, Dlamini S, Surendran S, Singh SK, Ahmad R, Holmes A, Rasheed MA, Mendelson M, Charani E 04/01/2024
Multi-ancestry meta-analysis of host genetic susceptibility to tuberculosis identifies shared genetic architecture. eLife Meta-Analysis, Journal Article Schurz H, Naranbhai V, Yates TA, Gilchrist JJ, Parks T, Dodd PJ, Möller M, Hoal EG, Morris AP, Hill AVS, International Tuberculosis Host Genetics Consortium 15/01/2024
Optimizing a linear ‘Doggybone’ DNA vaccine for influenza virus through the incorporation of DNA targeting sequences and neuraminidase antigen Discovery Immunology Journal Article Cunliffe RF, Stirling DC, Razzano I, Murugaiah V, Montomoli E, Kim S, Wane M, Horton H, Caproni LJ, Tregoning JS 01/01/2024
Palisade structure in intact vaccinia virions. mBio Journal Article Hernandez-Gonzalez M, Calcraft T, Nans A, Rosenthal PB, Way M 03/01/2024
Personalising intravenous to oral antibiotic switch decision making through fair interpretable machine learning. Nature Communications Journal Article Bolton WJ, Wilson R, Gilchrist M, Georgiou P, Holmes A, Rawson TM 13/01/2024
PLANNER: a multi-scale deep language model for the origins of replication site prediction. IEEE Journal of Biomedical and Health Informatics Journal Article Wang C, He Z, Jia R, Pan S, Coin LJ, Song J, Li F 04/01/2024
Protocol for the challenge non-typhoidal Salmonella (CHANTS) study: a first-in-human, in-patient, double-blind, randomised, safety and dose-escalation controlled human infection model in the UK. BMJ Open Clinical Trial Protocol, Journal Article, Research Support, Non-U.S. Gov’t Smith C, Smith E, Rydlova A, Varro R, Hinton JCD, Gordon MA, Choy RKM, Liu X, Pollard AJ, Chiu C, Cooke GS, Gibani MM 10/01/2024
Quantitative measurement of antibiotic resistance in Mycobacterium tuberculosis reveals genetic determinants of resistance and susceptibility in a target gene approach. Nature Communications Journal Article CRyPTIC Consortium 12/01/2024
Rapid nanopore sequencing and predictive susceptibility testing of positive blood cultures from intensive care patients with sepsis. Microbiology Spectrum Journal Article Harris PNA, Bauer MJ, Lüftinger L, Beisken S, Forde BM, Balch R, Cotta M, Schlapbach L, Raman S, Shekar K, Kruger P, Lipman J, Bialasiewicz S, Coin L, Roberts JA, Paterson DL, Irwin AD 09/01/2024
Re: Association of CMV DNAemia with Long-Term Mortality in a Randomized Trial of Preemptive Therapy (PET) and Antiviral Prophylaxis (AP) for Prevention of CMV Disease in High-Risk Donor Seropositive, Recipient Seronegative (D+R-) Liver Transplant Recipients. Clinical Infectious Diseases Journal Article Yates TA, Halliday N 09/01/2024
Recent advances in understanding the human host immune response in tuberculous meningitis. Frontiers in Immunology Journal Article, Review Barnacle JR, Davis AG, Wilkinson RJ 09/01/2024
Regeneration of actin filament branches from the same Arp2/3 complex. Science Advances Journal Article Ghasemi F, Cao L, Mladenov M, Guichard B, Way M, Jégou A, Romet-Lemonne G 26/01/2024
Reply to ‘Cognitive criteria in HIV: greater consensus is needed’. Nature Reviews Neurology Journal Article Nightingale S, Cinque P, Dravid A, Dreyer AJ, Gisslén M, Joska JA, Kwasa J, Meyer A-C, Mpongo N, Nakasujja N, Pebody R, Pozniak A, Price RW, Saylor D, Thomas KGF, Underwood J, Vera JH, Winston A 01/02/2024
Role of anaesthesia providers in infection-related care across the perioperative pathway: a global survey. British Journal of Anaesthesia Journal Article Birgand G, Biccard B, Deslandes A, Mbamalu O, Bonaconsa C, Boutall A, Mendelson M, Leone M, Ndoli J, Leather A, Holmes A, Moonesinghe R, Charani E 01/01/2024
Short-term and medium-term clinical outcomes of multisystem inflammatory syndrome in children: a prospective observational cohort study. Italian Journal of Pediatrics Observational Study, Journal Article Glazyrina A, Zholobova E, Iakovleva E, Bobkova P, Krasnaya E, Kovygina K, Romanova O, Blyuss O, Tutelman K, Petrova P, Bairashevskaia A, Rumyantsev M, Korsunskiy AA, Kondrikova E, Nargizyan A, Yusupova V, Korobyants E, Sologub A, Kurbanova S, Suvorov A, Sigfrid L, Buonsenso D, Peroni DG, McArdle AJ, Comberiati P, Munblit D 04/01/2024
Structural basis of σ54 displacement and promoter escape in bacterial transcription. Proceedings of the National Academy of Sciences of USA Journal Article Gao F, Ye F, Zhang B, Cronin N, Buck M, Zhang X 09/01/2024
Systematic functional analysis of the Com pilus in Streptococcus sanguinis: a minimalistic type 4 filament dedicated to DNA uptake in monoderm bacteria. mBio Journal Article Mom J, Chouikha I, Valette O, Pieulle L, Pelicic V 16/01/2024
T7 phage-assisted evolution of riboswitches using error-prone replication and dual selection. Scientific Reports Journal Article Goicoechea Serrano E, Blázquez-Bondia C, Jaramillo A 29/01/2024
The effect of ciprofloxacin prophylaxis during haematopoietic cell transplantation on infection episodes, exposure to treatment antimicrobials and antimicrobial resistance: a single-centre retrospective cohort study. JAC-Antimicrobial Resistance Journal Article Baltas I, Kavallieros K, Konstantinou G, Koutoumanou E, Gibani MM, Gilchrist M, Davies F, Pavlu J 01/02/2024
The stabilization of Arp2/3 complex generated actin filaments. Biochemical Society Transactions Journal Article Cao L, Way M 30/01/2024
Type I Lipoteichoic Acid (LTA) Detection by Western Blot. Methods in Molecular Biology Journal Article, Research Support, Non-U.S. Gov’t Millership C, Gründling A 11/10/2023
Virology, pathogenesis, epidemiology and clinical management of HTLV-1 infection. Proceedings of the 30th HTLV European research network (HERN 2023) Journal of Osteopathic Medicine Journal Article De Mendoza C, Taylor G, Gessain A, Thoma-Kress AK, Bangham C, Vesterbacka J, Accolla R, Bazarbachi A, Van Weyenbergh J, Cook L, Casseb J, Ramos JC, Rosadas C, Macchi B, Cassar O, Soriano V 01/01/2024
Which low urgent triaged febrile children are suitable for a fast track? An observational European study. Emergency Medicine Journal Journal Article Tan CD, Vermont CL, Zachariasse JM, von Both U, Carrol ED, Eleftheriou I, Emonts M, van der Flier M, Herberg J, Kohlmaier B, Levin M, Lim E, Maconochie IK, Martinon-Torres F, Nijman RG, Pokorn M, Rivero-Calle I, Rudzāte A, Tsolia M, Zenz W, Zavadska D, Moll HA, PERFORM consortium (Personalised Risk assessment in febrile children to optimise Real-life Management across the European Union) 18/01/2024
Plasma Protein Biomarkers Distinguish Multisystem Inflammatory Syndrome in Children From Other Pediatric Infectious and Inflammatory Diseases
The Pediatric Infectious Disease Journal Journal Article Yeoh S, Estrada-Rivadeneyra D, Jackson H , Keren I, Galassini R, Cooray S, Shah P, Agyeman P, Basmaci R, Carrol E, Emonts M, Fink C, Kuijpers T, Martinon-Torres F, Mommert-Tripon M, Paulus S, Pokorn M, Rojo P, Romani L, Schlapbach L, Schweintzger N, Shen C, Tsolia M, Usuf E, van der Flier M, Vermont C, von Both U, Yeung S, Zavadska D, Coin L, Cunnington A, Herberg J, Levin M, Kaforou M, Hamilton S; PERFORM; 7/02/2024