Congratulations to members of the Department who have recently had their research findings published. Here’s our round-up of the latest publication successes.
To ensure the quality and accuracy of the information published on this blog, we source our data directly from Symplectic. Our reports are generated on a monthly basis, which means there may be a delay in publicising some publications.
| Title | Canonical journal title | Publication type | Authors OR Author/Contributors | Publication date |
| “Getting pregnant during COVID-19 was a big risk because getting help from the clinic was not easy”: COVID-19 experiences of women and healthcare providers in Harare, Zimbabwe. | PLOS Global Public Health | Journal Article | Mupambireyi Z, Cowan FM, Chappell E, Chimwaza A, Manika N, Wedderburn CJ, Gannon H, Gibb T, Heys M, Fitzgerald F, Chimhuya S, Gibb D, Ford D, Mushavi A, Bwakura-Dangarembizi M | 08/01/2024 |
| A CRISPR-Cas12a-based platform facilitates the detection and serotyping of Streptococcus suis serotype 2 | Talanta | Article, Journal | Wang L, Sun J, Zhao J, Bai J, Zhang Y, Zhu Y, Zhang W, Wang C, Langford PR, Liu S, Li G | 15/01/2024 |
| A low-volume LC/MS method for highly sensitive monitoring of phenoxymethylpenicillin, benzylpenicillin, and probenecid in human serum. | Analytical Methods: advancing methods and applications | Journal Article | Riezk A, Wilson RC, Cass AEG, Holmes AH, Rawson TM | 25/01/2024 |
| A novel computational pipeline for var gene expression augments the discovery of changes in the Plasmodium falciparum transcriptome during transition from in vivo to short-term in vitro culture. | eLife | Journal Article | Andradi-Brown C, Wichers-Misterek JS, von Thien H, Höppner YD, Scholz JAM, Hansson H, Filtenborg Hocke E, Gilberger TW, Duffy MF, Lavstsen T, Baum J, Otto TD, Cunnington AJ, Bachmann A | 25/01/2024 |
| An assessment of the airborne longevity of group A Streptococcus. | Microbiology | Journal Article | Oswin HP, Blake E, Haddrell AE, Finn A, Sriskandan S, Reid JP, Halliday A, Goenka A | 01/01/2024 |
| Antagonistic interactions between phage and host factors control arbitrium lysis-lysogeny decision. | Nature Microbiology | Journal Article | Zamora-Caballero S, Chmielowska C, Quiles-Puchalt N, Brady A, Del Sol FG, Mancheño-Bonillo J, Felipe-Ruíz A, Meijer WJJ, Penadés JR, Marina A | 01/01/2024 |
| BACH1 promotes tissue necrosis and Mycobacterium tuberculosis susceptibility. | Nature Microbiology | Journal Article | Amaral EP, Namasivayam S, Queiroz ATL, Fukutani E, Hilligan KL, Aberman K, Fisher L, Bomfim CCB, Kauffman K, Buchanan J, Santuo L, Gazzinelli-Guimaraes PH, Costa DL, Teixeira MA, Barreto-Duarte B, Rocha CG, Santana MF, Cordeiro-Santos M, Barber DL, Wilkinson RJ, Kramnik I, Igarashi K, Scriba T, Mayer-Barber KD, Andrade BB, Sher A | 01/01/2024 |
| BridgePRS leverages shared genetic effects across ancestries to increase polygenic risk score portability. | Nature Genetics | Journal Article | Hoggart CJ, Choi SW, García-González J, Souaiaia T, Preuss M, O’Reilly PF | 01/01/2024 |
| Cortactin stabilizes actin branches by bridging activated Arp2/3 to its nucleated actin filament. | Nature Structural and Molecular Biology | Journal Article | Liu T, Cao L, Mladenov M, Jegou A, Way M, Moores CA | 24/01/2024 |
| Development and Implementation of Digital Diagnostic Algorithms for Neonatal Units in Zimbabwe and Malawi: Development and Usability Study. | JMIR Formative Research | Journal Article | Gannon H, Larsson L, Chimhuya S, Mangiza M, Wilson E, Kesler E, Chimhini G, Fitzgerald F, Zailani G, Crehan C, Khan N, Hull-Bailey T, Sassoon Y, Baradza M, Heys M, Chiume M | 26/01/2024 |
| Development and Validation of the Phoenix Criteria for Pediatric Sepsis and Septic Shock. | JAMA: Journal of the American Medical Association | Journal Article | Sanchez-Pinto LN, Bennett TD, DeWitt PE, Russell S, Rebull MN, Martin B, Akech S, Albers DJ, Alpern ER, Balamuth F, Bembea M, Chisti MJ, Evans I, Horvat CM, Jaramillo-Bustamante JC, Kissoon N, Menon K, Scott HF, Weiss SL, Wiens MO, Zimmerman JJ, Argent AC, Sorce LR, Schlapbach LJ, Watson RS, Society of Critical Care Medicine Pediatric Sepsis Definition Task Force, Biban P, Carrol E, Chiotos K, Flauzino De Oliveira C, Hall MW, Inwald D, Ishimine P, Levin M, Lodha R, Nadel S, Nakagawa S, Peters MJ, Randolph AG, Ranjit S, Souza DC, Tissieres P, Wynn JL | 21/01/2024 |
| Digital remote monitoring for screening and early detection of urinary tract infections. | npj Digital Medicine | Journal Article | Capstick A, Palermo F, Zakka K, Fletcher-Lloyd N, Walsh C, Cui T, Kouchaki S, Jackson R, Tran M, Crone M, Jensen K, Freemont P, Vaidyanathan R, Kolanko M, True J, Daniels S, Wingfield D, CR&T Group, Nilforooshan R, Barnaghi P | 13/01/2024 |
| Distinguishing community-acquired bacterial and viral meningitis: Microbes and biomarkers. | Journal of Infection | Journal Article, Review | Ivaska L, Herberg J, Sadarangani M | 01/02/2024 |
| DLL4/Notch3/WNT5B axis mediates bidirectional prometastatic crosstalk between melanoma and lymphatic endothelial cells. | JCI Insight | Journal Article | Alve S, Gramolelli S, Jukonen J, Juteau S, Pink A, Manninen AA, Hänninen S, Monto E, Lackman MH, Carpén O, Saharinen P, Karaman S, Vaahtomeri K, Ojala PM | 09/01/2024 |
| Effects of the COVID-19 pandemic on the outcomes of HIV-exposed neonates: a Zimbabwean tertiary hospital experience. | BMC Pediatrics | Journal Article, Research Support | Gannon H, Chappell E, Ford D, Gibb DM, Chimwaza A, Manika N, Wedderburn CJ, Nenguke ZM, Cowan FM, Gibb T, Phillips A, Mushavi A, Fitzgerald F, Heys M, Chimhuya S, Bwakura-Dangarembizi M | 05/01/2024 |
| Enhanced active case finding of drug-resistant tuberculosis in Namibia: a protocol for the hotspots, hospitals, and households (H3TB) study | BMJ Open | Journal Article | Shavuka O, Lipumbu E, Boois L, Gunther G, Hoddinott G, Lin H, Nepolo E, Niemann S, Ruswa N, Seddon J, Claassens M | 10/02/2024 |
| Evolution of enhanced innate immune suppression by SARS-CoV-2 Omicron subvariants. | Nature Microbiology | Journal Article | Reuschl A-K, Thorne LG, Whelan MVX, Ragazzini R, Furnon W, Cowton VM, De Lorenzo G, Mesner D, Turner JLE, Dowgier G, Bogoda N, Bonfanti P, Palmarini M, Patel AH, Jolly C, Towers GJ | 16/01/2024 |
| Factors associated with an increased risk of developing pneumonia during acute ischemic stroke hospitalization. | PLoS One | Observational Study, Journal Article | Jitpratoom P, Boonyasiri A | 10/01/2024 |
| Fifteen-minute consultation: Managing post-COVID-19 syndrome (long COVID) in children and young people | Archives of Disease in Childhood: Education and Practice Edition | Article, Early Access, Journal | Wacks M, Wortley E, Gregorowski A, Segal TY, Whittaker E | 23/01/2024 |
| Hepatic steatosis in people older and younger than fifty who are living with HIV and HIV-negative controls: A cross-sectional study nested within the POPPY cohort | HIV Medicine | Article, Early Access, Journal | Arenas-Pinto A, Bakewell N, Milinkovic A, Williams I, Vera J, Post FA, Anderson J, Beynon M, O’Brien A, Doyle N, Gilson R, Pett SL, Winston A, Sabin CA | 01/01/2024 |
| Histidine transport is essential for the growth of Staphylococcus aureus at low pH | PLoS Pathogens | Article | Beetham CM, Schuster CF, Kviatkovski I, Santiago M, Walker S, Gründling A | 16/01/2024 |
| How do socioeconomic determinants of health affect the likelihood of living with HTLV-1 globally? A systematic review with meta-analysis | Frontiers in Public Health | Journal Article | Ramesh N, Cockbain B, Taylor GP, Rosadas de Oliveira C | 01/01/2024 |
| How does the microbiota control systemic innate immunity? | Trends in Immunology | Journal Article, Review | Jordan CKI, Clarke TB | 11/01/2024 |
| HTLV-1 induces an inflammatory CD4+CD8+ T cell population in HTLV-1-associated myelopathy. | JCI Insight | Journal Article | Maher AK, Aristodemou A, Giang N, Tanaka Y, Bangham CR, Taylor GP, Dominguez-Villar M | 09/01/2024 |
| Hypertension care cascades and reducing inequities in cardiovascular disease in low- and middle-income countries. | Nature Medicine | Journal Article | Stein DT, Reitsma MB, Geldsetzer P, Agoudavi K, Aryal KK, Bahendeka S, Brant LCC, Farzadfar F, Gurung MS, Guwatudde D, Houehanou YCN, Malta DC, Martins JS, Saeedi Moghaddam S, Mwangi KJ, Norov B, Sturua L, Zhumadilov Z, Bärnighausen T, Davies JI, Flood D, Marcus ME, Theilmann M, Vollmer S, Manne-Goehler J, Atun R, Sudharsanan N, Verguet S | 26/01/2024 |
| Identification and management of co-infections in those with malaria | BMJ: British Medical Journal | Journal Article | Cunnington A, Abbara A, Kaduni Bawa F, Achan J | 13/03/2024 |
| Immune responses and clinical outcomes after COVID-19 vaccination in patients with liver disease and liver transplant recipients. | Journal of Hepatology | Journal Article | Murray SM, Pose E, Wittner M, Londoño M-C, Schaub G, Cook J, Dimitriadis S, Meacham G, Irwin S, Lim Z, Duengelhoef P, Sterneck M, Lohse AW, Perez V, Trivedi P, Bhandal K, Mullish BH, Manousou P, Provine NM, Avitabile E, Carroll M, Tipton T, Healy S, Burra P, Klenerman P, Dunachie S, Kronsteiner B, Maciola AK, Pasqual G, Hernandez-Gea V, Garcia-Pagan JC, Lampertico P, Iavarone M, Gines P, Lütgehetmann M, Schulze Zur Wiesch J, Russo FP, Barnes E, Marjot T, OCTAVE Collaborative Group, PITCH study, and the EASL supported COVID-Hep vaccine network | 01/01/2024 |
| Impact of pregnancy vaccine uptake and socio-demographic determinants on subsequent childhood Measles, Mumps and Rubella vaccine uptake: A UK birth cohort study. | Vaccine | Journal Article | Skirrow H, Foley K, Bedford H, Lewis C, Whittaker E, Costelloe C, Saxena S | 12/01/2024 |
| Impaired lung function in adolescents with pulmonary tuberculosis during treatment and following treatment completion. | EClinicalMedicine | Journal Article | van der Zalm MM, Jongen VW, Swanepoel R, Zimri K, Allwood B, Palmer M, Dunbar R, Goussard P, Schaaf HS, Hesseling AC, Seddon JA | 01/01/2024 |
| Integrated analysis of patient networks and plasmid genomes reveals a regional, multi-species outbreak of carbapenemase-producing Enterobacterales carrying both blaIMP and mcr-9 genes. | Journal of Infectious Diseases | Journal Article | Wan Y, Myall AC, Boonyasiri A, Bolt F, Ledda A, Mookerjee S, Weiße AY, Getino M, Turton JF, Abbas H, Prakapaite R, Sabnis A, Abdolrasouli A, Malpartida-Cardenas K, Miglietta L, Donaldson H, Gilchrist M, Hopkins KL, Ellington MJ, Otter JA, Larrouy-Maumus G, Edwards AM, Rodriguez-Manzano J, Didelot X, Barahona M, Holmes AH, Jauneikaite E, Davies F | 20/01/2024 |
| International Consensus Criteria for Pediatric Sepsis and Septic Shock. | JAMA: Journal of the American Medical Association | Journal Article | Schlapbach LJ, Watson RS, Sorce LR, Argent AC, Menon K, Hall MW, Akech S, Albers DJ, Alpern ER, Balamuth F, Bembea M, Biban P, Carrol ED, Chiotos K, Chisti MJ, DeWitt PE, Evans I, Flauzino de Oliveira C, Horvat CM, Inwald D, Ishimine P, Jaramillo-Bustamante JC, Levin M, Lodha R, Martin B, Nadel S, Nakagawa S, Peters MJ, Randolph AG, Ranjit S, Rebull MN, Russell S, Scott HF, de Souza DC, Tissieres P, Weiss SL, Wiens MO, Wynn JL, Kissoon N, Zimmerman JJ, Sanchez-Pinto LN, Bennett TD, Society of Critical Care Medicine Pediatric Sepsis Definition Task Force | 21/01/2024 |
| Mentorship as an overlooked dimension of research capacity strengthening: how to embed value-driven practices in global health. | BMJ Global Health | Journal Article | Bonaconsa C, Nampoothiri V, Mbamalu O, Dlamini S, Surendran S, Singh SK, Ahmad R, Holmes A, Rasheed MA, Mendelson M, Charani E | 04/01/2024 |
| Multi-ancestry meta-analysis of host genetic susceptibility to tuberculosis identifies shared genetic architecture. | eLife | Meta-Analysis, Journal Article | Schurz H, Naranbhai V, Yates TA, Gilchrist JJ, Parks T, Dodd PJ, Möller M, Hoal EG, Morris AP, Hill AVS, International Tuberculosis Host Genetics Consortium | 15/01/2024 |
| Optimizing a linear ‘Doggybone’ DNA vaccine for influenza virus through the incorporation of DNA targeting sequences and neuraminidase antigen | Discovery Immunology | Journal Article | Cunliffe RF, Stirling DC, Razzano I, Murugaiah V, Montomoli E, Kim S, Wane M, Horton H, Caproni LJ, Tregoning JS | 01/01/2024 |
| Palisade structure in intact vaccinia virions. | mBio | Journal Article | Hernandez-Gonzalez M, Calcraft T, Nans A, Rosenthal PB, Way M | 03/01/2024 |
| Personalising intravenous to oral antibiotic switch decision making through fair interpretable machine learning. | Nature Communications | Journal Article | Bolton WJ, Wilson R, Gilchrist M, Georgiou P, Holmes A, Rawson TM | 13/01/2024 |
| PLANNER: a multi-scale deep language model for the origins of replication site prediction. | IEEE Journal of Biomedical and Health Informatics | Journal Article | Wang C, He Z, Jia R, Pan S, Coin LJ, Song J, Li F | 04/01/2024 |
| Protocol for the challenge non-typhoidal Salmonella (CHANTS) study: a first-in-human, in-patient, double-blind, randomised, safety and dose-escalation controlled human infection model in the UK. | BMJ Open | Clinical Trial Protocol, Journal Article, Research Support, Non-U.S. Gov’t | Smith C, Smith E, Rydlova A, Varro R, Hinton JCD, Gordon MA, Choy RKM, Liu X, Pollard AJ, Chiu C, Cooke GS, Gibani MM | 10/01/2024 |
| Quantitative measurement of antibiotic resistance in Mycobacterium tuberculosis reveals genetic determinants of resistance and susceptibility in a target gene approach. | Nature Communications | Journal Article | CRyPTIC Consortium | 12/01/2024 |
| Rapid nanopore sequencing and predictive susceptibility testing of positive blood cultures from intensive care patients with sepsis. | Microbiology Spectrum | Journal Article | Harris PNA, Bauer MJ, Lüftinger L, Beisken S, Forde BM, Balch R, Cotta M, Schlapbach L, Raman S, Shekar K, Kruger P, Lipman J, Bialasiewicz S, Coin L, Roberts JA, Paterson DL, Irwin AD | 09/01/2024 |
| Re: Association of CMV DNAemia with Long-Term Mortality in a Randomized Trial of Preemptive Therapy (PET) and Antiviral Prophylaxis (AP) for Prevention of CMV Disease in High-Risk Donor Seropositive, Recipient Seronegative (D+R-) Liver Transplant Recipients. | Clinical Infectious Diseases | Journal Article | Yates TA, Halliday N | 09/01/2024 |
| Recent advances in understanding the human host immune response in tuberculous meningitis. | Frontiers in Immunology | Journal Article, Review | Barnacle JR, Davis AG, Wilkinson RJ | 09/01/2024 |
| Regeneration of actin filament branches from the same Arp2/3 complex. | Science Advances | Journal Article | Ghasemi F, Cao L, Mladenov M, Guichard B, Way M, Jégou A, Romet-Lemonne G | 26/01/2024 |
| Reply to ‘Cognitive criteria in HIV: greater consensus is needed’. | Nature Reviews Neurology | Journal Article | Nightingale S, Cinque P, Dravid A, Dreyer AJ, Gisslén M, Joska JA, Kwasa J, Meyer A-C, Mpongo N, Nakasujja N, Pebody R, Pozniak A, Price RW, Saylor D, Thomas KGF, Underwood J, Vera JH, Winston A | 01/02/2024 |
| Role of anaesthesia providers in infection-related care across the perioperative pathway: a global survey. | British Journal of Anaesthesia | Journal Article | Birgand G, Biccard B, Deslandes A, Mbamalu O, Bonaconsa C, Boutall A, Mendelson M, Leone M, Ndoli J, Leather A, Holmes A, Moonesinghe R, Charani E | 01/01/2024 |
| Short-term and medium-term clinical outcomes of multisystem inflammatory syndrome in children: a prospective observational cohort study. | Italian Journal of Pediatrics | Observational Study, Journal Article | Glazyrina A, Zholobova E, Iakovleva E, Bobkova P, Krasnaya E, Kovygina K, Romanova O, Blyuss O, Tutelman K, Petrova P, Bairashevskaia A, Rumyantsev M, Korsunskiy AA, Kondrikova E, Nargizyan A, Yusupova V, Korobyants E, Sologub A, Kurbanova S, Suvorov A, Sigfrid L, Buonsenso D, Peroni DG, McArdle AJ, Comberiati P, Munblit D | 04/01/2024 |
| Structural basis of σ54 displacement and promoter escape in bacterial transcription. | Proceedings of the National Academy of Sciences of USA | Journal Article | Gao F, Ye F, Zhang B, Cronin N, Buck M, Zhang X | 09/01/2024 |
| Systematic functional analysis of the Com pilus in Streptococcus sanguinis: a minimalistic type 4 filament dedicated to DNA uptake in monoderm bacteria. | mBio | Journal Article | Mom J, Chouikha I, Valette O, Pieulle L, Pelicic V | 16/01/2024 |
| T7 phage-assisted evolution of riboswitches using error-prone replication and dual selection. | Scientific Reports | Journal Article | Goicoechea Serrano E, Blázquez-Bondia C, Jaramillo A | 29/01/2024 |
| The effect of ciprofloxacin prophylaxis during haematopoietic cell transplantation on infection episodes, exposure to treatment antimicrobials and antimicrobial resistance: a single-centre retrospective cohort study. | JAC-Antimicrobial Resistance | Journal Article | Baltas I, Kavallieros K, Konstantinou G, Koutoumanou E, Gibani MM, Gilchrist M, Davies F, Pavlu J | 01/02/2024 |
| The stabilization of Arp2/3 complex generated actin filaments. | Biochemical Society Transactions | Journal Article | Cao L, Way M | 30/01/2024 |
| Type I Lipoteichoic Acid (LTA) Detection by Western Blot. | Methods in Molecular Biology | Journal Article, Research Support, Non-U.S. Gov’t | Millership C, Gründling A | 11/10/2023 |
| Virology, pathogenesis, epidemiology and clinical management of HTLV-1 infection. Proceedings of the 30th HTLV European research network (HERN 2023) | Journal of Osteopathic Medicine | Journal Article | De Mendoza C, Taylor G, Gessain A, Thoma-Kress AK, Bangham C, Vesterbacka J, Accolla R, Bazarbachi A, Van Weyenbergh J, Cook L, Casseb J, Ramos JC, Rosadas C, Macchi B, Cassar O, Soriano V | 01/01/2024 |
| Which low urgent triaged febrile children are suitable for a fast track? An observational European study. | Emergency Medicine Journal | Journal Article | Tan CD, Vermont CL, Zachariasse JM, von Both U, Carrol ED, Eleftheriou I, Emonts M, van der Flier M, Herberg J, Kohlmaier B, Levin M, Lim E, Maconochie IK, Martinon-Torres F, Nijman RG, Pokorn M, Rivero-Calle I, Rudzāte A, Tsolia M, Zenz W, Zavadska D, Moll HA, PERFORM consortium (Personalised Risk assessment in febrile children to optimise Real-life Management across the European Union) | 18/01/2024 |
| Plasma Protein Biomarkers Distinguish Multisystem Inflammatory Syndrome in Children From Other Pediatric Infectious and Inflammatory Diseases |
The Pediatric Infectious Disease Journal | Journal Article | Yeoh S, Estrada-Rivadeneyra D, Jackson H , Keren I, Galassini R, Cooray S, Shah P, Agyeman P, Basmaci R, Carrol E, Emonts M, Fink C, Kuijpers T, Martinon-Torres F, Mommert-Tripon M, Paulus S, Pokorn M, Rojo P, Romani L, Schlapbach L, Schweintzger N, Shen C, Tsolia M, Usuf E, van der Flier M, Vermont C, von Both U, Yeung S, Zavadska D, Coin L, Cunnington A, Herberg J, Levin M, Kaforou M, Hamilton S; PERFORM; | 7/02/2024 |