Congratulations to members of the Department who have recently had their research findings published. Here’s our round-up of the latest publication successes.
To ensure the quality and accuracy of the information published on this blog, we source our data directly from Symplectic. Our reports are generated on a monthly basis, which means there may be a delay in publicising some publications.
| Title | Canonical Journal Title | Publication Type | Authors OR Authors/Contributors | Publication date |
| A mechanistic evaluation of human beta defensin 2 mediated protection of human skin barrier in vitro. | Scientific Reports | Journal Article | Shelley JR, McHugh BJ, Wills J, Dorin JR, Weller R, Clarke DJ, Davidson DJ | 08/02/2023 |
| A Phase I/II Open-Label Study of Molibresib for the Treatment of Relapsed/Refractory Hematologic Malignancies. | Clinical Cancer Research | Clinical Trial, Phase II, Clinical Trial, Phase I, Journal Article, Research Support, Non-U.S. Gov’t | Dawson MA, Borthakur G, Huntly BJP, Karadimitris A, Alegre A, Chaidos A, Vogl DT, Pollyea DA, Davies FE, Morgan GJ, Glass JL, Kamdar M, Mateos M-V, Tovar N, Yeh P, Delgado RG, Basheer F, Marando L, Gallipoli P, Wyce A, Krishnatry AS, Barbash O, Bakirtzi E, Ferron-Brady G, Karpinich NO, McCabe MT, Foley SW, Horner T, Dhar A, Kremer BE, Dickinson M | 16/02/2023 |
| A single-arm, long-term efficacy and safety study of subcutaneous romiplostim in children with immune thrombocytopenia. | Blood Advances | Multicenter Study, Clinical Trial, Phase III, Journal Article, Research Support, Non-U.S. Gov’t | Grainger J, Bussel J, Tarantino M, Cooper N, Beam D, Despotovic J, Maschan A, Wang K, Eisen M, Bowers C | 14/02/2023 |
| An expert consensus to define how higher standards of equitable care for von Willebrand disease can be achieved in the UK and Republic of Ireland. | Haemophilia | Journal Article | Laffan M, Benson G, Farrelly C, Gomez K, Jones A, Maclean R, O’Donnell J, Lavin M | 06/03/2023 |
| Atypical lymphocytes-From chickenpox to monkey pox | American Journal of Hematology | Editorial Material, Early Access, Editorial material, Journal | Nesr G, Whittaker E, Bain BJ | 27/02/2023 |
| Autoantibodies enhance ADAMTS13 clearance in patients with immune thrombotic thrombocytopenic purpura | Journal of Thrombosis and Haemostasis | Journal Article | Underwood MI, Alwan F, Thomas MR, Scully MA, Crawley JTB | 01/02/2023 |
| Biopsy-proven fungal pyelonephritis complicating delayed graft function in a renal transplant patient | BMJ Case Reports | Article, Journal | Jesuthasan A, Roufosse C, Ramaswami A | 01/02/2023 |
| CAR-iNKT cells targeting clonal TCRVβ chains as a precise strategy to treat T cell lymphoma | Frontiers in Immunology | Article | Rowan A, Ponnusamy K, Ren H, Taylor G, Cook L, Karadimitris A | 02/03/2023 |
| Exaggerated responses to a virus long gone. | Science | Journal Article | Brodin P | 10/02/2023 |
| Genetic mechanisms of 184 neuro-related proteins in human plasma. | Preprint | Repetto L, Chen J, Yang Z, Zhai R, Timmers PRHJ, Li T, Twait EL, May-Wilson S, Muckian MD, Prins BP, Png G, Kooperberg C, Johansson Å, Hillary RF, Wheeler E, Pan L, He Y, Klasson S, Ahmad S, Peters JE, Gilly A, Karaleftheri M, Tsafantakis E, Haessler J, Gyllensten U, Harris SE, Wareham NJ, Göteson A, Lagging C, Ikram MA, van Duijn CM, Jern C, Landén M, Langenberg C, Deary IJ, Marioni RE, Enroth S, Reiner AP, Dedoussis G, Zeggini E, Butterworth AS, Mälarstig A, Wilson JF, Navarro P, Shen X | 14/02/2023 | |
| GLI1, a novel target of the ER stress regulator p97/VCP, promotes ATF6f-mediated activation of XBP1. | Biochimica et Biophysica Acta: Gene Regulatory Mechanisms | Journal Article | Almada LL, Barroso K, Sen S, Toruner M, Sigafoos AN, Raja Arul GL, Pease DR, Vera RE, Olson RLO, Auner HW, Pedeux R, Iovanna JL, Chevet E, Fernandez-Zapico ME | 25/02/2023 |
| Hemoglobinopathies: From Diagnosis to Specialized Consultancy | British Journal of Haematology | Book Review, Review, Journal | Bain BJ | 01/02/2023 |
| High patient satisfaction and increased physical activity following a remote multidisciplinary team multiple myeloma clinic | Supportive Care in Cancer | Article, Journal | Lecat CSY, Fisher A, Atta M, Camilleri M, McCourt O, Land J, Worthington S, Hart A, Daniel A, Uddin I, Roche C, Auner HW, Yong K | 01/02/2023 |
| Immunoglobulin, glucocorticoid, or combination therapy for multisystem inflammatory syndrome in children: a propensity-weighted cohort study. | The Lancet Rheumatology | Journal Article | Channon-Wells S, Vito O, McArdle AJ, Seaby EG, Patel H, Shah P, Pazukhina E, Wilson C, Broderick C, D’Souza G, Keren I, Nijman RG, Tremoulet A, Munblit D, Ulloa-Gutierrez R, Carter MJ, Ramnarayan P, De T, Hoggart C, Whittaker E, Herberg JA, Kaforou M, Cunnington AJ, Blyuss O, Levin M, Best Available Treatment Study (BATS) consortium | 14/02/2023 |
| Integrating biological HLA-DPB1 mismatch models to predict survival after unrelated hematopoietic cell transplantation. | Haematologica: the hematology journal | Letter, Research Support, Non-U.S. Gov’t | Ruggeri A, De Wreede LC, Müller CR, Crivello P, Bonneville EF, Petersdorf EW, Socié G, Dubois V, Niittyvuopio R, Peräsaari J, Yakoub-Agha I, Cornelissen JJ, Wieten L, Gedde-Dahl T, Forcade E, Crawley CR, Marsh SGE, Gandemer V, Tholouli E, Bulabois C-E, Huynh A, Choi G, Deconinck E, Itäla-Remes M, Lenhoff S, Bengtsson M, Johansson J-E, Van Gorkom G, Hoogenboom JD, Vago L, Rocha V, Bonini C, Chabannon C, Fleischhauer K | 01/02/2023 |
| Neutralising antibody potency against SARS-CoV-2 wild-type and omicron BA.1 and BA.4/5 variants in patients with inflammatory bowel disease treated with infliximab and vedolizumab after three doses of COVID-19 vaccine (CLARITY IBD): an analysis of a prospective multicentre cohort study. | The Lancet Gastroenterology & Hepatology | Observational Study, Multicenter Study, Journal Article, Research Support, Non-U.S. Gov’t | Liu Z, Le K, Zhou X, Alexander JL, Lin S, Bewshea C, Chanchlani N, Nice R, McDonald TJ, Lamb CA, Sebastian S, Kok K, Lees CW, Hart AL, Pollok RC, Boyton RJ, Altmann DM, Pollock KM, Goodhand JR, Kennedy NA, Ahmad T, Powell N, CLARITY study investigators | 01/02/2023 |
| Ophthalmic presentation of chronic myeloid leukemia in two adolescents. | American Journal of Hematology | Case Reports | Badat M, Sivaguru G, Bain BJ | 16/02/2023 |
| The C-terminal domains of ADAMTS1 contain exosites involved in its proteoglycanase activity. | Journal of Biological Chemistry | Journal Article | Minns A, Qi Y, Yamamoto K, Lee K, Ahnström J, Santamaria S | 20/02/2023 |
| The Mental Health Burden of Patients with Colorectal Cancer Receiving Care during the COVID-19 Pandemic: Results of the PICO-SM Study. | Cancers | Journal Article | Lim KHJ, Ntellas P, Anderson D, Simpson L, Braun M, Adamou M, Barriuso J, Dadouli K, Connell J, Williams J, Germetaki T, Lehwald D, Fitzpatrick N, Cutting M, McCool D, Hasan J, Mullamitha S, Marti K, Saunders M, Kamposioras K | 15/02/2023 |
| The person-to-person transmission landscape of the gut and oral microbiomes. | Nature | Journal Article | Valles-Colomer M, Blanco-Míguez A, Manghi P, Asnicar F, Dubois L, Golzato D, Armanini F, Cumbo F, Huang KD, Manara S, Masetti G, Pinto F, Piperni E, Punčochář M, Ricci L, Zolfo M, Farrant O, Goncalves A, Selma-Royo M, Binetti AG, Becerra JE, Han B, Lusingu J, Amuasi J, Amoroso L, Visconti A, Steves CM, Falchi M, Filosi M, Tett A, Last A, Xu Q, Qin N, Qin H, May J, Eibach D, Corrias MV, Ponzoni M, Pasolli E, Spector TD, Domenici E, Collado MC, Segata N | 01/02/2023 |
| The role of CD8+ T cell clones in immune thrombocytopenia. | Blood | Journal Article | Malik A, Sayed AA, Han P, Tan MMH, Watt E, Constantinescu-Bercu A, Cocker ATH, Khoder A, Saputil RC, Thorley EV, Teklemichael A, Ding Y, Hart ACJ, Zhang H, Mitchell WA, Imami N, Crawley JTB, Salles-Crawley II, Bussel JB, Zehnder JL, Adams SP, Zhang BM, Cooper N | 07/02/2023 |
| Total serum N-glycans associate with response to immune checkpoint inhibition therapy and survival in patients with advanced melanoma | BMC Cancer | Article, Journal | Visconti A, Rossi N, Deris H, Lee KA, Hanic M, Trbojevic-Akmacic I, Thomas AM, Bolte LA, Bjork JR, Hooiveld-Noeken JS, Board R, Harland M, Newton-Bishop J, Harries M, Sacco JJ, Lorigan P, Shaw HM, de Vries EGE, Fehrmann RSN, Weersma RK, Spector TD, Nathan P, Hospers GAP, Sasieni P, Bataille V, Lauc G, Falchi M | 18/02/2023 |
| Transcriptome analysis reveals tumor microenvironment changes in glioblastoma. | Cancer Cell | Journal Article | Hoogstrate Y, Draaisma K, Ghisai SA, van Hijfte L, Barin N, de Heer I, Coppieters W, van den Bosch TPP, Bolleboom A, Gao Z, Vincent AJPE, Karim L, Deckers M, Taphoorn MJB, Kerkhof M, Weyerbrock A, Sanson M, Hoeben A, Lukacova S, Lombardi G, Leenstra S, Hanse M, Fleischeuer REM, Watts C, Angelopoulos N, Gorlia T, Golfinopoulos V, Bours V, van den Bent MJ, Robe PA, French PJ | 03/03/2023 |
| Traumatic coagulopathy in the older patient: analysis of coagulation profiles from the Activation of Coagulation and Inflammation in Trauma-2 (ACIT-2) observational, multicenter study. | Journal of Thrombosis and Haemostasis | Multicenter Study, Journal Article, Research Support, Non-U.S. Gov’t | Curry NS, Davenport R, Wong H, Gaarder C, Johansson P, Juffermans NP, Maegele M, Stensballe J, Brohi K, Laffan M, Stanworth SJ | 01/02/2023 |
| Two-Year Outcomes of Valoctocogene Roxaparvovec Therapy for Hemophilia A. | New England Journal of Medicine | Clinical Trial, Phase III, Journal Article, Multicenter Study | Mahlangu J, Kaczmarek R, von Drygalski A, Shapiro S, Chou S-C, Ozelo MC, Kenet G, Peyvandi F, Wang M, Madan B, Key NS, Laffan M, Dunn AL, Mason J, Quon DV, Symington E, Leavitt AD, Oldenburg J, Chambost H, Reding MT, Jayaram K, Yu H, Mahajan R, Chavele K-M, Reddy DB, Henshaw J, Robinson TM, Wong WY, Pipe SW, GENEr8-1 Trial Group | 23/02/2023 |