Author: Elena Corujo Simon

Injecting Hope – Vaccine development in a pandemic

Earlier this June, people at Imperial College London had the opportunity to hear from a scientist who affected all our lives, Professor Dame Sarah Gilbert from the Pandemic Sciences Institute at the University of Oxford. The Department of Life Sciences hosted Prof Gilbert for the Sir Ernst Chain lecture, a celebration of the late biochemist who developed the techniques to isolate and produce Penicillin, together with Howard Florey and Alexander Fleming.

Prof Gilbert works on viral vector vaccines. In 2020 she led the group who, together with Astra Zeneca, developed and produced one of the Covid-19 vaccines. The Oxford/Astra Zeneca (ChAdOx1 nCov-19) vaccine was used in 180 countries. It is estimated to have saved over 6 million lives in the first year it was used!

Our guest blogger, Arabella Heath wrote a blog post about her talk and how combination of molecular science and engineering was crucial for vaccine development in a pandemic.

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Insect wings – tackling antimicrobial resistance

Last April, Arabella Heath, a Biochemistry undergraduate student, and Mia Hughes, a Chemistry undergraduate, joined IMSE for a day to experience the work environment in an Operations team. Together, they explored the topic of antimicrobial resistance and how we can keep antibiotics working by combining molecular science and engineering research. Coincidentally, a couple of weeks ago, the U.K. government updated its strategy to tackle antimicrobial resistance for the next 5 years. In this blog, Arabella and Mia explore how the surface of insect wings is inspiring innovation on antimicrobial ‘smart’ surfaces to reduce bacterial infections in hospitals.

The prevalence of antimicrobial resistance

Summer is approaching, and we are all dreading the familiar sound of insects buzzing that accompanies the season. But who knew that studying some insects like cicadas and dragonflies might hold the key to tackling antimicrobial resistance (AMR)? AMR occurs when antimicrobial treatment is no longer effective at treating bacteria, viruses, fungi and other parasites. It leads to increased infections rates and severe illnesses. AMR is a major threat for the development of global public health. AMR caused an estimated 1.27 million deaths in 2019 worldwide and this is set to rise to 10 million by 2050. This issue requires new and innovative solutions because evolving bacteria are outsmarting our current available antibiotics.

Steps on how antibiotic resistance happens. 1. Lots of germs, some are drug resistant. 2. Antibiotics kill the bacteria causing the illness, as well as good bacteria protecting the body from infection. 3. The drug-resistant bacteria are now allowed to grow and take over. 4. Some bacteria give their drug-resistance to other bacteria, causing more problems.
How Antibiotic Resistance happens. Image credit: Lumen learning.

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Giving textile waste and dyes a second chance

Following on our blogs exploring circular economy and zero waste, we welcome our new guest blogger, Dr. Antonio Ovejero-Perez. A postdoc from the Department of Chemical Engineering, Antonio’s research is focused on extracting dyes from textiles waste. 

Who hasn’t heard a family member say: “Back in the day, I only got new clothing for Christmas or birthday”? Now, in our fast-paced world things have changed. How many times a year do we buy clothes? Trends come and go quickly, and “fast fashion” has become more and more popular. 

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Upcycling palm oil waste to mitigate climate change

Let’s check our shopping list, does it include items such as shampoo, detergent, margarine or cookies? According to the WWF, it is highly likely that some or all these items contain palm oil. You have probably heard about the negative connection between palm oil and deforestation and displacement of wildlife. However, you might be unaware of the large amount of waste generated during its production. Here, IMSE’s latest guest blogger, PhD researcher from Future Materials Group,  Dharu Smaradhana, discusses his research into waste generated by palm oil production and its potential as sustainable material.

Palm oil is criticised due to deforestation concerns, but replacing it with other vegetable oils is not a straightforward solution. Palm oil is the most land-efficient vegetable oil crop. It supplies 40% of the world’s demand while using less than 6% of the land allocated for all vegetable oil production. Alternatives like soybean, coconut or sunflower oil require considerably more land which could lead to additional environmental damage.

Comparison of palm oil yields to other vegetable oils.
Comparison of palm oil yields to other vegetable oils. Image credit: Valori news

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Multidisciplinary approach to Zero Waste

Have you ever given an object a second life? Reusing yogurt pots to grow plants or a mug with a broken handle turned into a pencil holder. I recently made cushions out of coffee beans sacks from the nearby roasters. You probably also recycle glass bottles and carry a tote bag when going shopping, reducing the number of plastic bags.

Empty yogurt pots used to grow plants.
Re-using yogurt pots to grow plants. Image credit: Flickr, Ilja Klutman.

From linear to circular economy

These are all examples of a circular economy. Established as a concept in the 70s, circular economy is the system of production and consumption that reduces waste to a minimum. Extending a product’s life is achievable by re-using, repairing, recycling and sharing, all of which create further value. Circular economy is the opposite of the linear economy model, where goods are simply thrown away after use.

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