By IGHI guest blogger Chanice Henry, Editor, Pharma IQ & Pharma Logistics IQ
Similar to new Hollywood feature Rampage, a recent study has urged the life sciences industry not to underestimate the dangers that could hide within CRISPR Cas9.
Although the film has been criticised for wildly exaggerating the capabilities of the gene editing technique, it can be recognised for its effort to draw focus from the excitable buzz around CRISPR Cas9 towards the importance of considering the ethics and dangers associated with the tool.
A recent commentary piece also emphasised the importance of methodically debating the potential outcomes of CRISPR within the task of tackling Malaria.
By IGHI guest blogger, Chris Bird,PG student in the Centre for Health Policy and Project Manager in the System Engagement Programme at the National Institute for Health and Care Excellence (NICE)
Systems under pressure
Health systems around the world face the twin pressures of a rising demand for services, coupled with financial pressure on resources to deliver them. For publicly-funded universal health services in developed countries such as the UK’s National Health Service (NHS), new investment is at an all-time low. Funding for the NHS in England has seen a real-terms rise of 4.4% over 6 years, meaning that the average annual rise was just 0.7% per year.
By guest bloggers Sophie Uyoga and Charles Kamau, Research Scientists in Kilifi, Kenya
Most blood prescribed for transfusion in the developing world is mainly in emergency care. According to the WHO 2015 Report on Road Safety, the African Region has the highest risk of road traffic accident, one of the greatest contributors of emergencies needing blood transfusions. However, hospitals in this region are constantly facing blood stock outs, greatly contributes to the poor outcome all forms of medical emergencies as well as among admissions with severe anaemia. A clinical trial in East Africa by Kiguli et al., demonstrated how timely access reduces the risk of mortality among children with severe anaemia with a high proportion of those not transfused dying within 2.5 hours post admission.
5 May 2017 marked the International Day of the Midwife. Recognising the important role that midwives play to families and mothers, the day was first established in 1992. Midwives endure rigorous training to ensure that they can provide quality care for those in need. The level of skills amongst midwives however, can vary across the world.
March 2017 saw the arrival of Dr Beverly Donaldson, her midwifery colleagues Maggie Welch and Judith Robbins and paediatrician Dr Anna Battersby from Imperial College London/Imperial NHS Trust to facilitate the third midwifery training programme at the MRC Fajara The Gambia. The aim of the training was to support local midwives in their clinical practice by teaching them the necessary skills to manage basic obstetric emergencies in order to save the lives of mothers and babies in their care.
By Dr Kike Olajide, Wellcome Global Health Clinical Research Fellow, Centre for Psychiatry, Imperial College London.
Globally, the number of people with depression and anxiety is on the rise – up from 416 million in 1990 to 615 million in 2013. The World Health Organisation estimates that mental illness is now the leading cause of disability worldwide, accounting for over 15% of years lost due to disability (YLD). In addition to disability, common mental illnesses such as depression can lead to suicide. If you are aged 15 to 29 and living in Europe, the thing most likely to kill you, is you – suicide is the leading cause of death in this age group.
Approximately 1200 African children are estimated to die from malaria every day, accounting for the vast majority of the global deaths from this disease. Over the past decade there has been an unprecedented increase in funding for malaria-control activities and vaccine development – the two major tools in ‘Roll back Malaria’ prevention and elimination programme. This has resulted in major scaling-up in the distribution of bed nets treated with long-lasting insecticides and public-private funding for late phase multi-site trials of the most promising anti-malaria vaccine candidate developed to date (RTS,S).
Khayelitsha, a peri-urban township outside of Cape Town, South Africa, has some of the highest rates of HIV and TB in the world. Many members of this community have had personal experiences with TB and HIV, either being directly infected or as a result of the death of loved ones. This is also the setting for a major clinical research site established by The Clinical Infectious Diseases Research Initiative (CIDRI). The research group, which focusses on finding better ways to intervene in and understand HIV-associated TB, was established by Professor Robert Wilkinson and has laboratory and academic space at the Institute of Infectious Disease and Molecular Medicine (IDM).