Category: Infection

Celebrating Women at IGHI: Driving Meaningful Change in Global Health

On International Women’s Day, we shine a spotlight on the incredible women at the Institute of Global Health Innovation (IGHI) who are shaping the future of healthcare worldwide. From pioneering research to innovative policy work, these leaders are tackling some of the most pressing global health challenges —making a real difference in in the UK and beyond.

In this blog, we celebrate their achievements and highlight how their expertise and dedication continue to inspire change. Read on to learn about some of these fantastic women at the IGHI and discover key examples of their work.

Professor Bryony Dean Franklin – Visiting Professor at IGHI

Professor Bryony Dean Franklin is visiting Professor in the Department of Surgery and Cancer at the Centre for Prevention and Management at Imperial College.

Health in Ukraine: Prioritise health care reform across the Ukraine health system for recovery and stable peace

Two years on from the invasion of Ukraine, we share a series of blog posts highlighting insights from our Ukraine Health Summit last year, hosted in partnership with the British Red Cross to reflect on and support the delivery and restoration of health services in Ukraine.

The second blog post focuses on the prioritisation of health care reform across the Ukraine health system for recovery and stable peace, and is written by Niki O’Brien, Institute of Global Health Innovation, Imperial College London, with colleagues.

The war in Ukraine has caused substantial disruption to a health system that was already having to manage complex transitions.

As a research topic, Long Covid found me

I usually say that as a research topic ‘Long Covid’ found me.

In March 2020 I was busy with my research in cancer early diagnosis, learning health systems and artificial intelligence for improving diagnosis in primary care. I caught COVID-19 in mid-March, just before the first lockdown, with moderate symptoms; cough, fever, but my blood oxygen levels were fine.

How wearables could help tackle sepsis

Our immune system serves to protect our bodies from threats, such as rogue cells that could turn cancerous, or infections that could harm our health. But the immune system can also go wrong, and do more harm than good.

This is what happens in sepsis, or “blood poisoning”, where the immune system goes into overdrive while attempting to clear an invader, such as harmful bacteria, and inadvertently attacks person’s tissues and organs. This life-threatening reaction is estimated to affect close to 150,000 people each year in the UK alone.

World Sepsis Day, on September 13th, seeks to raise awareness of this serious condition, which could take as many as 6 million lives across the globe each year.

Eliminating Viral Hepatitis: ‘Missing Millions or Missing Billions’

By Professor Mark Thursz, Professor of Hepatology within the Department of Surgery and Cancer, Imperial College London

According to the World Health Organisation it is estimated that 250 million people worldwide are chronically infected with the hepatitis B virus (HBV) and 70 million with the hepatitis C virus (HCV). Untreated, these infections can lead to premature death from cirrhosis and liver cancer; recent statistics suggest that together HBV and HCV are responsible for more deaths than HIV.

Ending stigma and HIV transmission

By Dr Julia Makinde is a Research Associate with the International AIDS Vaccine Initiative at Imperial College London

It is estimated that there are 36.7 million people living with HIV globally with 1.8 million new infections in 2016 alone (1). This number represents an 11% drop in the number of new infections from 2010 . Some might consider this an achievement or a testament to the impact of strategic national and global policies aimed at tackling the epidemic. But in reality, these numbers mask the discrepant pace in the effort to tackle transmission and AIDS-related deaths in countries across the globe.

Hepatitis: Why early screening matters

By Professor Mark Thursz, Professor of Hepatology within the Department of Surgery and Cancer, Imperial College London

Five viruses, hepatitis A – E, specifically infect the liver and cause acute hepatitis or chronic hepatitis.

Over 350 million people worldwide are chronically infected and are therefore at risk of cirrhosis, liver failure and liver cancer. Hepatitis B and Hepatitis C virus are together responsible for over a million deaths per year. The majority of infections and deaths related to these viruses occur in low and middle income countries. In 2010 the United Nations World Health Assembly passed a resolution which recognised the burden of disease imposed by these viruses and initiated a public health response to viral hepatitis which included the inception of World Hepatitis Day.

Topical issues in STIs: going beyond testing at the Jefferiss Wing centre for Sexual Health

By Dr Angela Bailey, Consultant HIV/GU medicine, Imperial College Healthcare NHS Trust

The Jefferiss Wing at St Mary’s hospital is one of the biggest sexual health clinics in the UK. As well as providing services for testing (walk in and bookable online), we have an active Clinical Trials Centre and many of our clinicians are involved in sexual health research which gives our patients a chance to participate in studies and access to the latest developments in STI care. Some key areas, which have been in the news over the last year, are discussed here.

Putting TB to the test: My journey so far

By Harriet Gliddon, winner of the IGHI Student Challenges Competition 2015-16

During March 2016, I blogged for IGHI on World TB Day about my experiences of entering the Student Challenges Competition.

The intervening six months have been busier than I could have imagined, and filled with things like delivering an invited talk at the Biosensors Summit in Sweden, submitting my PhD thesis and completing an internship at the World Health Organization.

Despite the chaos, I’ve managed to make some exciting advances with the nanomaterial-based diagnostic test for TB that I presented at the Student Challenges Competition. One component of this work has focused on validating the genetic markers that are the biological targets, or biomarkers, of the test.