Blog posts

A Marginal Call in Breast Cancer

By Mr Daniel Leff, Reader in Breast Surgery, Department of Surgery & Cancer, Faculty of Medicine  As we move towards the end of Breast Cancer Awareness month, it is important to celebrate the many success of breast cancer research and treatment  – whilst breast cancer may be common, more women than ever before are surviving thanks to earlier diagnosis and an improved understanding of the biology of breast cancer leading to more personalised medicine. That said, we still face major challenges. The one that is on the forefront of my mind is the “margins problem” once called the ‘hidden epidemic of breast cancer’.

Keeping the heart healthy in October – Cholesterol Awareness Month

By Lily Roberts, Centre Assistant for Centre for Health Policy and Patient Safety Translational Research Centre

As the month of October approaches for 2018, we’re reminded by Heart UK to bring awareness to the risks of having high cholesterol levels.

Eliminating Viral Hepatitis: ‘Missing Millions or Missing Billions’

By Professor Mark Thursz, Professor of Hepatology within the Department of Surgery and Cancer, Imperial College London

According to the World Health Organisation it is estimated that 250 million people worldwide are chronically infected with the hepatitis B virus (HBV) and 70 million with the hepatitis C virus (HCV). Untreated, these infections can lead to premature death from cirrhosis and liver cancer; recent statistics suggest that together HBV and HCV are responsible for more deaths than HIV.

Improving blood transfusion systems using an evidence-based approach

By Chris Bird, MSc Health Policy student at Imperial College and Project Manager in the System Engagement Programme at NICE

Today mark’s World Blood Donor Day – an event to celebrate and thank volunteers the world over, who generously donate blood to support life-saving care and to raise awareness of the continued need for donations of blood and blood products to support high quality safe care for patients who need it most.

Towards safer and more equitable maternal health care

by Ana Luisa Neves, General Practitioner and Research Associate at Imperial NIHR PSTRC

Making motherhood safe is a human rights imperative. In the last 20 years, a steady decline has been observed in maternal mortality rates worldwide, but much more needs to be done: nearly 300,000 women still die every year because of pregnancy or childbirth-related complications (1). This means that a mother dies every two minutes.

From Flatbush New York to London, via Paris: Ketosis-prone type 2 diabetes, a distinct form of diabetes we’re only beginning to understand

By Dr Shivani Misra, Honorary Clinical Research Fellow, Faculty of Medicine, Department of Medicine

This Diabetes Week, it’s important to remember that there are more than just two types of diabetes and how global insights into ethnic-specific types can benefit local people with diabetes.

New asthma treatment candidate provides hope to millions

By IGHI guest blogger Chanice Henry, Pharma IQ

Researchers have uncovered a new drug candidate that could relieve millions of people who are under-served by current asthma treatments.  

Asthma is a relatively common disease that hinders the respiration of over 300 million individuals globally, leading to episodes of wheezing, chest tightness and other severe problems.

Limitations

Indeed inhalers and other medications exist to manage the disease. However, many of these manufactured treatments have critical side effects and fail to provide relief for around one-third of asthma suffers. Bronchodilator inhalers are used by the majority of asthma suffers and although effective in treating respiratory conditions there are still some gaps in understanding on how and why these inhalers work.

Launching the NHS Digital Academy

By Rachel Dunscombe, CEO, NHS Digital Academy

Standing in the Royal Society on the 16th of April waiting for the participants to arrive was both surreal and exciting. Surreal because of the rapid journey our wonderful team had taken to make the programme happen – this had become a reality so quickly. Exciting because I couldn’t wait to get started – this programme is important for the system and for me something I am hugely committed to.

The Digital Academy operational team, of which I am a part, are all keen to ensure that this programme is as grounded in digital leaders’ practice as much as possible rather than being too high end academic.

Malaria research: Scientist industry urged to not underestimate CRISPR’s risks

By IGHI guest blogger Chanice Henry, Editor, Pharma IQ & Pharma Logistics IQ

Similar to new Hollywood feature Rampage, a recent study has urged the life sciences industry not to underestimate the dangers that could hide within CRISPR Cas9.

Although the film has been criticised for wildly exaggerating the capabilities of the gene editing technique, it can be recognised for its effort to draw focus from the excitable buzz around CRISPR Cas9 towards the importance of considering the ethics and dangers associated with the tool.

A recent commentary piece also emphasised the importance of methodically debating the potential outcomes of CRISPR within the task of tackling Malaria.

Mosquitoes, human health and environmental change

By Paul Huxley, Research Postgraduate, Faculty of Medicine, School of Public Health

Ronald Ross, a British medical doctor of the late-19th and early 20th centuries, was first to identify the mosquito as the winged-insect carrier of malaria-causing parasites. Prior to this breakthrough, bad air (mal aria in Italian) was thought to have been the culprit. Together, Ross and Giovanni Grassi (who’s work, unlike Ross’, was controversially ignored by the Nobel Committee in 1902) uncovered a truth of huge ecological and epidemiological significance and sparked an ongoing international research effort aimed at answering fundamental questions about the processes that drive patterns of human morbidity and mortality caused by diseases carried by mosquitoes.