On Mesothelioma Awareness Day, Dr Anca Nastase provides an insight into mesothelioma and how research advances offer new hope for improved treatment.
Mesothelioma Awareness Day represents a great opportunity to gain more information about the disease biology, risk factors or symptoms from everyone in the mesothelioma community. Raising awareness is essential as it has the potential to improve prevention and early diagnosis and can translate into better outcomes and better survival for the patients.
My aim as a scientist within the National Centre for Mesothelioma Research (NCMR) is to deepen the molecular research in mesothelioma and to advance our understanding of the mechanisms responsible for the onset and progression of this disease.
Although progress has been made in the field, further understanding of the pathophysiology is still desperately needed.
Mesothelioma is a type of cancer that arises and develops in the thin layer that covers the human internal organs, called mesothelium.
Kelly Gleason, CRUK Lead Nurse, explores the value of patient and public involvement in cancer research and how it can improve the quality and outcomes of research.
Patient and public involvement (PPI) is increasingly recognised as important. Funding bodies are asking for more and more from researchers in regard to patient and public involvement. They want to see evidence of authentic and ongoing relationships between researchers and the public that is informing what is being researched, how it is being researched and how findings are shared with the public. Funders want to see more co-creation between researchers and the public and for this to happen, researchers require help accessing larger patient networks and support in maintaining relationships with patients.
My journey with PPI at Imperial
I became involved in patient and public involvement almost a decade ago – it was a relatively novel concept back then. The need for cancer researchers to access patients to involve in their research was increasing. The Imperial Cancer Research UK Centre, where I work as a Lead Nurse, established a group of patients and members of the public for Imperial researchers to have easy access to the patient voice. The group served as a resource to researchers and inputted on everything from grant proposals to lay summaries. They helped us create a research culture at Imperial where patients were integral to what and how we carried out cancer research. (more…)
This festive period Three Wise Women from the Faculty of Medicine will be giving us the gift of wisdom.
Our first is Professor Gerry Thomas, a leading authority on the health impacts of radiation, who tells us why we should focus on the facts.
I was born in the 1960s and grew up believing that the word ‘radiation’ meant something that was infinitely dangerous. Back then, we were led to believe that nuclear weapons would lead to the extinction of our species, and that to be bitten by a radioactive spider would confer supernatural powers! I was therefore sceptical about the use of nuclear power. It wasn’t until 1992, when I started to study the health effects of the accident at the Chernobyl nuclear power station in 1986, that I began to question whether my understanding of the health effects of radiation came more from science fiction than scientific fact. (more…)
This Breast Cancer Awareness Month, Dr Luca Magnani unravels the complexity of cancer research, from recent advances in genomics to the power of patients in research.
In today’s fast-paced world in which everything quickly rotates, spins loudly for your clicks and sights, deciding where to focus our attention is a decisive factor. When trends come and go at lightning pace, it is somewhat surprising that October is still Breast Cancer Awareness Month. I’m glad we can still manage to stop and reflect on what this means. Last year we discussed how Breast Cancer Awareness Month has evolved in the era of social media and marketing. This year I thought we could be more optimistic and discuss when October becomes ‘tea and crumpet’ appreciation month. (more…)
An eye-opening account by Professor Sir Tony Newman Taylor on how asbestos has gone from ‘magic mineral’ to deadly dust that can cause mesothelioma.
Public awareness of the hazards of asbestos can be dated to the period immediately following the death of Nellie Kershaw aged 33 in 1924. She had worked during the previous seven years in a textile factory spinning asbestos fibre into yarn. She died of severe fibrosis of the lungs. The pathologist, William Cooke, who found retained asbestos fibres in the lungs, called the cause of death asbestosis. Nellie Kershaw was not the first case to be reported of lung fibrosis caused by asbestos. Montague Murray in 1899 had reported the case of a 33-year-old man who had worked for 14 years in an asbestos textile factory. He had died of fibrosis of the lungs which Montague Murray, also finding asbestos in the lungs, had attributed to inhaled asbestos fibres. The patient had told Murray he was the only survivor from ten others who had worked in his workshop. (more…)
Dr Tim Hoogenboom, a Research Sonographer, looks at the promise and perils of machine learning in medical imaging.
Medical imaging is key in today’s delivery of modern healthcare, with an immense 41 million imaging tests taking place in England in every year. Thousands upon thousands of patients safely undergo imaging procedures such as X-ray, ultrasound, and MRI every day, and the product of these tests – the images – play an essential role in informing the decisions of medical professionals and patients in nearly every area of disease. (more…)
To mark World AIDS Day 2017, we have published a series of blog posts to highlight the important and varied research that takes places at Imperial. Three experts from Faculty of Medicine share their interest in HIV/AIDS which spans from the elusive vaccine to the economics of the epidemic.
World AIDS Day takes place annually on 1 December as an opportunity for people worldwide to unite in the fight against HIV and to show support for people living with HIV/AIDS.
Oncologist turned HIV expert
As a medical oncologist at Chelsea and Westminster Hospital, I specialise in the treatment of HIV-related cancers at the National Centre for HIV Malignancy – Europe’s largest research and treatment institute for these cancers. Over the last 25 years, I have seen an astonishing improvement in the outcomes of people diagnosed with both HIV and cancer, so that patients under my care with most HIV associated cancers now have the same overall survival as HIV negative patients. (more…)
To mark Movember, PhD student Akifumi Shibakawa explains how Movember cash is funding prostate cancer research at Imperial and how to get involved in the fundraising.
It’s that time of the year again, when men grow moustaches around the globe. It all started in 2003, when two guys in Australia had the idea to make moustache-growing fashionable again. For a greater cause, they made this campaign about men’s health and established the Movember Foundation. As you may know, the campaign became an international phenomenon, attracting over 300,000 participants in more than 20 countries in 2016. (more…)
For Alcohol Awareness Week, Professor David Nutt explains how his latest research venture, an alcohol-free beverage, could address the dangers associated with alcohol consumption.
Most of us are aware that chronic, heavy alcohol consumption and binge drinking leads to a plethora of health issues including liver damage and addiction. However, many of us are still unaware of the dangers associated with even moderate alcohol consumption or the cumulative effects that alcohol can have on our health. So just what are those regular trips to the pub, or the frequent cocktails after work really costing us? (more…)
PhD student Philippa May reflects on being a scientist in the field blood cancer, from working in a leukaemia diagnostic laboratory to a research laboratory.
For the last 10 years I have been a clinical scientist in genetics working across various London NHS Trusts. Whilst I loved diagnostics, last year I left my job to complete my PhD. I worked in a part of life sciences called cytogenetics. This meant when a patient was diagnosed with blood cancer, I would analyse their chromosomes – the structures into which DNA is organised – from their blood or bone marrow to look for specific abnormalities. For some patients, this can lead to a definitive diagnosis. For others a refined prognosis, and in some, it’s simply a way of monitoring how well the patient’s leukaemia is responding to their treatment. (more…)