Tag: Disease awareness

My Day in the Living Lab: could I help accelerate drug trials?

Rory-Cellan-Jones

Rory Cellan-Jones is an author and former BBC Technology Correspondent who, in 2019, was diagnosed with Parkinson’s Disease. Rory discusses his visit to the ‘Living Lab’ at the UK DRI Care Research & Technology Centre – a unique mock apartment where scientists can monitor the behaviour of patients in a domestic environment.

My week started with quite a stressful day. For nearly five hours I was under the microscope, my every move watched by scientists. They made me walk up and down, rise from a chair without using my arms, open and close my hand rapidly. I spent half an hour staring at a computer screen trying to work out which shape fitted where on a grid, one of a number of cognition tests. They even made me make two cups of tea and four slices of toast.

It was tiring but it was all in the cause of science – and potentially faster drug trials. This all took place in Imperial College’s Living Lab, a room fitted out like a small flat on the ninth floor of a tower block in West London. The lab is equipped with video cameras and a series of sensors which provide data on its occupants’ activities.

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Targeting both incretin receptors together for a new generation of diabetes therapies

Close up of woman's hands checking blood sugar level using glucose meter

Dr Alejandra Tomas, Senior Lecturer at the Department of Metabolism, Digestion and Reproduction, explores new and emerging incretin-based therapies for managing diabetes.

Diabetes is a disease that has reached epidemic proportions, with millions of people dying or suffering from a myriad of associated complications. Given that cases are projected to increase worldwide over the coming decades – especially in low- and middle-income countries – there is an urgent need to develop and deploy effective treatments for the disease.

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Alzheimer’s disease: why your genes aren’t always your destiny

For Dementia Action Week, Kitty Murphy, second year PhD student at the UK DRI Centre at Imperial, shares the complex nature of Alzheimer’s disease and why there’s more to it than just our genes.

Dementia diagnosis rates are dropping for the first time ever. I wish I could tell you that this is due to less people developing dementia, and not because more people are living with it undiagnosed. According to research carried out by Alzheimer’s Society, many people are not being diagnosed due to the misconception that memory loss is a normal part of aging. However, memory loss is often an early sign of dementia, particularly in the most common cause known as Alzheimer’s disease. As a result, the Alzheimer’s Society’s Dementia Action Week, an annual awareness campaign, has made diagnosis their featured theme.

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From bench to bedside and back again in mesothelioma

On Mesothelioma Awareness Day, Dr Anca Nastase provides an insight into mesothelioma and how research advances offer new hope for improved treatment.

Mesothelioma Awareness Day represents a great opportunity to gain more information about the disease biology, risk factors or symptoms from everyone in the mesothelioma community. Raising awareness is essential as it has the potential to improve prevention and early diagnosis and can translate into better outcomes and better survival for the patients.

My aim as a scientist within the National Centre for Mesothelioma Research (NCMR) is to deepen the molecular research in mesothelioma and to advance our understanding of the mechanisms responsible for the onset and progression of this disease.

Although progress has been made in the field, further understanding of the pathophysiology is still desperately needed.

Mesothelioma is a type of cancer that arises and develops in the thin layer that covers the human internal organs, called mesothelium.

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The Asbestos Story: a tale of public health and politics

The Asbestos Story: a tale of public health and politicsAn eye-opening account by Professor Sir Tony Newman Taylor on how asbestos has gone from ‘magic mineral’ to deadly dust that can cause mesothelioma.

Public awareness of the hazards of asbestos can be dated to the period immediately following the death of Nellie Kershaw aged 33 in 1924.  She had worked during the previous seven years in a textile factory spinning asbestos fibre into yarn. She died of severe fibrosis of the lungs. The pathologist, William Cooke, who found retained asbestos fibres in the lungs, called the cause of death asbestosis.  Nellie Kershaw was not the first case to be reported of lung fibrosis caused by asbestos. Montague Murray in 1899 had reported the case of a 33-year-old man who had worked for 14 years in an asbestos textile factory. He had died of fibrosis of the lungs which Montague Murray, also finding asbestos in the lungs, had attributed to inhaled asbestos fibres.  The patient had told Murray he was the only survivor from ten others who had worked in his workshop. (more…)

Think peach: the true symbol of breast cancer awareness

Breast cancer awareness

Breast cancer researcher, Dr Luca Magnani, looks beyond the pink ribbon campaign to find the true symbol of breast cancer awareness.

It’s that time of year once again: Instagram and Twitter will adopt a light shade of pink, companies will adorn their products with the ubiquitous pink ribbon, all to remind us of Breast Cancer Awareness Month. To a breast cancer scientist such as myself, October always brings out ambiguous emotions. On one side, it serves as a reminder of all the great research and results that we have achieved. Statistics show that things are getting better for many women, as mortality rates have halved in the last 20 years. October also prompts many of us to remember that there is nothing better than prevention when talking about breast cancer. Early screening measures have revolutionised outcomes for women; it’s very likely that almost 50% of the lives that were saved depended on catching the cancer earlier. (more…)