Author: Blogs Admin

Grandfather of allergy: Dr William Frankland, the 106-year-old doctor

Dr William (Bill) Frankland, aged 106, has helped transform our understanding of allergies during his long career in medicine. A pioneer in the field, Dr Frankland popularised the pollen count to help clinicians and patients understand what triggers their seasonal allergies. Originally published on the Imperial College Healthcare NHS Trust blog and reproduced here with permission, he reflects on his career and working for the NHS for 70 years. 

People often ask me, how is it that I’ve lived until 106. All I can say is I’ve come close to death so many times but somehow I’ve always managed to miss it and that’s why I’m still here.

I was born in 1912, six weeks early. My identical twin brother and I weighed three pounds one ounce each but we both survived – he died in 1995, at age 83. As an early baby, that’s the first time I survived against the odds.

I first encountered hay fever when I was a child. I grew up in the Lake District where my brother and I spent our summers helping a local farmer with his hay. One day, I told my brother my eyes were itchy and I couldn’t go on. “You’re feeble,” he said. It took me 30 years before I realised I had a real problem with summer hay fever and about 90 years to grow out of that allergy.

(more…)

From friend to foe: what drives MS to turn our immune systems against us?

For MS Awareness Week, Dr Rachel James and Dr Carmen Picon Muno from our Department of Brain Sciences explain how their efforts in understanding the mechanism behind MS is driving the search for new drug targets. 

I have always been fascinated by how the immune system protects our body by identifying attackers and fighting them off. It’s a remarkable undertaking: it must recognise and protect us from any number of harmful molecules produced by a huge array of invading organisms. Sometimes, however, this system can go wrong. For instance, in the case of multiple sclerosis (MS), the immune system erroneously attacks the myelin – a fatty covering that protects our nerves – in our own central nervous system. This produces the chronic accumulation of demyelinated MS lesions that lead to the clinical symptoms of the disease. (more…)

Smoke and the burnout of muscles

Image: Shutterstock - SMOKE & THE BURNOUT OF MUSCLESFor World No Tabaco Day 2017, researchers from Imperial’s Muscle Lab provide an insight into how smoking takes its toll on our lung health. 

Smoking is a leading cause of preventable death and disease in the world. It is estimated that the society costs associated with smoking are approximately ₤12.9 billion a year, including the NHS cost of treating smoking related diseases and loss of productivity.

Chronic obstructive pulmonary disease (COPD) is one of the major diseases caused by smoking. The disease ranks third among the leading causes of death worldwide. Around 1.2 million Britons suffer from the disease (Source: British Lung Foundation). The usual clinical picture is that of a smoker with symptoms that include shortness of breath and chronic cough. (more…)